公开(公告)号：US10072044B2

公开(公告)日：2018-09-11

申请号：US15180031

申请日：2016-06-12

Applicant: Yeda Research and Development Co. Ltd.

Inventor： Michal Schwartz-Eisenbach ,  Matityahu Fridkin ,  Michal Cardon-Yaakov

IPC: A61K9/00 ,  A61K38/00 ,  C07K7/06 ,  C07K7/64

CPC classification number: C07K7/06 ,  A61K9/0053 ,  A61K38/00 ,  C07K7/64

Abstract: The present application provides synthetic modified peptides of five to seven natural or non-natural amino acids as well as pharmaceutical compositions comprising them, for use in the treatment a disease or disorder presenting behavioral abnormalities associated with impairment of sensory gating function, depression or cognitive impairment, particularly schizophrenia and Alzheimer's disease.