公开(公告)号：US20200300829A1

公开(公告)日：2020-09-24

申请号：US16894916

申请日：2020-06-08

Applicant: Yeda Research and Development Co. Ltd.

Inventor： Noam SOBEL ,  Shani AGRON ,  Kobi SNITZ ,  Ethan LIVNE ,  Ofer PERL ,  Kineret WEISSLER ,  Aharon RAVIA ,  Danielle Ricca HONIGSTEIN ,  Maya FINKEL

IPC: G01N33/00

Abstract: A method of assessing odors, comprises providing an electronic nose that extracts measurements from odors, from which measurements at least n chemical descriptors are extracted where n is greater than unity, and typically around 18. The electronic nose is applied to an odor, and odor information is extracted. The information is plotted to a first location on an n-dimensional sample space, each dimension being related to a respective one of the n chemical descriptors or otherwise optimized for the particular enose and the measurements it makes; and an assessment of the odor is provided based on the plotted location. The assessment may be a description based on odor describing terms, or may be a chemical description in terms of chemicals that can synthesize the odor, and the odor may then be synthesized based on the chemical description.

公开(公告)号：US20180161300A1

公开(公告)日：2018-06-14

申请号：US15571071

申请日：2016-05-10

Applicant: Yeda Research And Development Co. Ltd.

Inventor： Ayelet EREZ ,  Shiran RABINOVICH ,  Alon SILBERMAN ,  Shani AGRON

IPC: A61K31/216 ,  A61P35/00 ,  A61K31/713 ,  A61K31/513 ,  C12N15/113 ,  A61K45/06

CPC classification number: A61K31/216 ,  A61K31/198 ,  A61K31/513 ,  A61K31/713 ,  A61K45/06 ,  A61P35/00 ,  C12N15/113 ,  C12N2310/14 ,  C12N2310/531

Abstract: Provided are methods, pharmaceutical compositions and kits for treating cancer in a subject in need thereof, by administering to the subject a therapeutically effective amount of an agent which downregulates a mitochondrial aspartate-dependent pyrimidine synthesis, thereby treating the cancer.