公开(公告)号：US20220364175A1

公开(公告)日：2022-11-17

申请号：US17846157

申请日：2022-06-22

Applicant: Yeda Research and Development Co. Ltd. ,  UCL Business Ltd

Inventor： Eran HORNSTEIN ,  Iddo MAGEN ,  Nancy-Sarah YACOVZADA ,  Jonathan ROHRER ,  Pietro FRATTA

IPC: C12Q1/6883 ,  G01N33/68

Abstract: A method of diagnosing Frontotemporal dementia (FTD) in a subject in need thereof is provided. The method comprising detecting a level of at least one micro RNA (miR) selected from the group consisting of hsa-miR-361-5p, hsa-miR-629-5p, hsa-miR-628-3p, hsa-miR-379-5p, hsa-miR-1-3p, hsa-miR-26a-5p, hsa-miR-125a-5p, hsa-miR-125b-5p, hsa-miR-142-5p and hsa-miR-340-5p in a biological sample of the subject, wherein when said level of said at least one micro RNA (miR) is higher than that in a control sample, it is indicative of FTD.