公开(公告)号：US06180673B2

公开(公告)日：2001-01-30

申请号：US09269161

申请日：1999-03-23

申请人： Yoichi Iwaki ,  Ikuo Tobari ,  Susumu Okamoto ,  Tatsuro Sakai

发明人： Yoichi Iwaki ,  Ikuo Tobari ,  Susumu Okamoto ,  Tatsuro Sakai

IPC分类号： A61K31195

CPC分类号： A61K31/192

摘要： The present invention relates to a corneal subepithelial opacity (haze) inhibitor comprising as the active ingredient N-(3,4-dimethoxycinnamoyl)anthranilic acid represented by the formula: or a pharmaceutically acceptable salt thereof, is useful for the prevention or treatment of corneal subepithelial opacity (haze) caused by a wound during the operation of refractive surgery such as keratectomy and radial keratotomy, and an external wound.

摘要翻译： 本发明涉及包含作为活性成分的由下式表示的N-（3,4-二甲氧基肉桂酰基）邻氨基苯甲酸的角膜上皮不透明度（雾度）抑制剂或其药学上可接受的盐，可用于预防或治疗角膜 在屈光手术如角膜切除术和径向角膜切开手术期间由伤口引起的上皮下不透明度（浑浊）和外伤。