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公开(公告)号:US11535901B2
公开(公告)日:2022-12-27
申请号:US16142073
申请日:2018-09-26
申请人: Yonsei University Industry Foundation (Yonsei UIF) , Korea University Research and Business Foundation, Sejong Campus
发明人: Seung Joo Haam , Hyun Ouk Kim , Byung Hoon Kang , Seung Min Han , Ji Sun Ki , Dae Sub Song , Woon Sung Na , Min Joo Yeom
IPC分类号: C12Q1/6876 , C12Q1/6818 , C12Q1/70
摘要: Provided herein are a probe capable of simultaneously detecting a virus and treating virus-infected cells, a composition for detecting a virus, which comprises the probe, a composition for treating a virus, which comprises the probe, and a method of detecting a virus or treating a viral infection by using the same. According to the present disclosure, it is possible to simultaneously perform diagnosis by virus detection and treatment of virus-infected cells, and in particular, diagnosis and treatment may be simultaneously performed on various types of viruses by varying the type of molecular beacon, and thus may be usefully applied to virus diagnosis and treatment fields, which require rapid diagnosis and treatment, and the spread of viral infections may be effectively prevented. In addition, the probe of the present disclosure has excellent stability and excellent detection sensitivity, and thus enables the detection of even a very low amount of a target at the pmole level.