DRUG FOR PREVENTING AND TREATING ATHEROSCLEROSIS
    4.
    发明申请
    DRUG FOR PREVENTING AND TREATING ATHEROSCLEROSIS 审中-公开
    用于预防和治疗甲状腺功能亢进的药物

    公开(公告)号:US20090082303A1

    公开(公告)日:2009-03-26

    申请号:US12274736

    申请日:2008-11-20

    IPC分类号: A61K31/7088

    摘要: The present invention relates to a prophylactic/therapeutic agent for atherosclerosis comprising GM3 synthase inhibitor or inhibitor for expression of GM3 synthase gene, a diagnostic product for atherosclerosis comprising antibody to GM3 synthase, a method of diagnosis for atherosclerosis using antibody to GM3 synthase and others, an use of GM3 or GM3 synthase for diagnostic marker of atherosclerosis, and the like.

    摘要翻译: 本发明涉及动脉粥样硬化的预防/治疗剂,其包含GM3合酶抑制剂或GM3合酶基因表达抑制剂,包含GM3合酶抗体的动脉粥样硬化诊断产物,使用抗GM3合成酶的动脉粥样硬化诊断方法等, 使用GM3或GM3合成酶作为动脉粥样硬化的诊断标志物等。

    Prophylactic/Therapeutic Agent for Cancer
    5.
    发明申请
    Prophylactic/Therapeutic Agent for Cancer 审中-公开
    预防/治疗癌症治疗剂

    公开(公告)号:US20090047282A1

    公开(公告)日:2009-02-19

    申请号:US11886846

    申请日:2006-03-24

    摘要: The present invention provides a prophylactic/therapeutic agent for cancer or the like, an agent for promoting apoptosis of cancer cells, an agent for suppressing proliferation of cancer cells, and the like, which comprises a compound or its salt that inhibits an activity of a protein comprising the same or substantially the same amino acid sequence as the amino acid sequence represented by SEQ ID NO: 1, a compound or its salt that inhibits the expression of a gene for the protein, an antisense polynucleotide comprising the entirety or part of a nucleotide sequence complementary or substantially complementary to a nucleotide sequence of a polynucleotide encoding the protein or its partial peptide, an antibody against the protein, or the like.

    摘要翻译: 本发明提供了癌症等的预防/治疗剂,促进癌细胞凋亡的药剂,抑制癌细胞增殖的药剂等,其包含抑制癌细胞增殖的化合物或其盐 包含与SEQ ID NO:1表示的氨基酸序列相同或基本相同的氨基酸序列的蛋白质,抑制蛋白质基因表达的化合物或其盐,包含全部或部分 与编码蛋白质或其部分肽的多核苷酸的核苷酸序列互补或基本互补的核苷酸序列,针对蛋白质的抗体等。