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公开(公告)号:US20080194688A1
公开(公告)日:2008-08-14
申请号:US12100075
申请日:2008-04-09
申请人: Yoshio SATO , Seiya MAKINO , Nobuo YODA , Kakuhei ISAWA , Tomonori KAMIYAMA , Kenichi HOJO , Mizue SAITO , Naoki TAKETOMO , Keisuke FURUICHI , Shuji IKEGAMI
发明人: Yoshio SATO , Seiya MAKINO , Nobuo YODA , Kakuhei ISAWA , Tomonori KAMIYAMA , Kenichi HOJO , Mizue SAITO , Naoki TAKETOMO , Keisuke FURUICHI , Shuji IKEGAMI
IPC分类号: A61K31/192 , A61P1/00 , A61P19/08
CPC分类号: C12P7/42 , A23L33/10 , A61K31/192
摘要: A composition containing 1,4-dihydroxy-2-naphthoic acid at a high concentration is obtained by intracellularly and extracellularly producing 1,4-dihydroxy-2-naphthoic acid using a bacterium belonging to the genus Propionibacterium and collecting it. This composition is efficacious in improving intestinal flora, alleviating abdominal ailments in association with the intake of milk, and preventing metabolic bone diseases.
摘要翻译: 通过使用属于丙酸杆菌属的细菌并通过细胞内和细胞外产生1,4-二羟基-2-萘甲酸,得到高浓度的含有1,4-二羟基-2-萘甲酸的组合物。 该组合物有效改善肠道菌群,减轻与摄入牛奶相关的腹部疾病,并预防代谢性骨病。