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公开(公告)号：US20100285056A1
公开(公告)日：2010-11-11
申请号：US12812053
申请日：2009-01-09
申请人： Young-Bong Kim , Hee Jung Lee , Nuri Park , Yu-Kyoung Oh
发明人： Young-Bong Kim , Hee Jung Lee , Nuri Park , Yu-Kyoung Oh
CPC分类号： A61K39/12 , A61K2039/5256 , C12N7/00 , C12N15/86 , C12N2710/14143 , C12N2710/14145 , C12N2710/14171 , C12N2710/20034 , C12N2740/10022 , C12N2800/22 , C12N2810/6054 , C12N2830/60 , C12N2830/85
摘要： The present invention relates to a recombinant baculovirus comprising: (a) a nucleotide sequence encoding a foreign virus envelope protein; (b) a first promoter operatively linked to the envelope-encoding nucleotide sequence; (c) a nucleotide sequence encoding an antigen protein; and (d) a second promoter operatively linked to the antigen-encoding nucleotide sequence; and a vaccine composition using the same. The recombinant baculovirus of the present invention has an excellent efficacy on both humoral and cellular immune responses against a specific antigen (e.g., HPV L1), enabling to function as a more efficient DNA vaccine.
摘要翻译： 本发明涉及重组杆状病毒，其包含：（a）编码外来病毒包膜蛋白的核苷酸序列; （b）可操作地连接到包膜编码核苷酸序列的第一启动子; （c）编码抗原蛋白的核苷酸序列; 和（d）与抗原编码核苷酸序列可操作地连接的第二启动子; 和使用其的疫苗组合物。 本发明的重组杆状病毒对针对特异性抗原（例如HPV L1）的体液和细胞免疫应答具有优异的功效，能够起到更有效的DNA疫苗的作用。
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2.发明申请公开(公告)号：US20090094299A1
公开(公告)日：2009-04-09
申请号：US12287338
申请日：2008-10-08
申请人： Jung-Hwan Kim , Seong-Jun Ahu , Young-Bong Kim , Young-II Seo , Chan-Ho Park
发明人： Jung-Hwan Kim , Seong-Jun Ahu , Young-Bong Kim , Young-II Seo , Chan-Ho Park
CPC分类号： G06F3/0643 , G06F3/0613 , G06F3/064 , G06F3/068
摘要： An apparatus and method for defragmenting files on a hybrid hard disk are provided. The apparatus includes a nonvolatile memory located within the hybrid hard disk, a loading unit reading data of a fragmented cluster and temporarily storing the read data in the nonvolatile memory, and a writing unit writing the temporarily stored data in contiguous clusters.
摘要翻译： 提供了一种用于在混合硬盘上对文件进行碎片整理的装置和方法。 该装置包括位于混合硬盘内的非易失性存储器，读取碎片集群的数据并将读取的数据临时存储在非易失性存储器中的装载单元，以及将临时存储的数据写入连续簇中的写入单元。
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