公开(公告)号：US10745370B2

公开(公告)日：2020-08-18

申请号：US16087103

申请日：2017-03-20

申请人： Yu-Jen Chen

发明人： Yu-Jen Chen ,  Lie-Chwen Lin

IPC分类号： C07D311/22 ,  A61P37/06 ,  A61P25/28 ,  A61P35/00

摘要： Disclosed herein are novel compounds and uses thereof. The present compounds may suppress the activity of farnesyl transferase and thus, may act as modulators of immune cells; therefor, they are useful for the development of a medicament for treating diseases that are associated with or caused by excessive levels of farnesyl transferase or immune response. Also disclosed herein are pharmaceutical compositions containing the present compounds.