公开(公告)号：US06992178B2

公开(公告)日：2006-01-31

申请号：US10416178

申请日：2001-10-17

申请人： Yukio Kato ,  Shinichi Tsutsumi ,  Ryo Oda ,  Hideaki Shintani ,  Masahiro Nishimura

发明人： Yukio Kato ,  Shinichi Tsutsumi ,  Ryo Oda ,  Hideaki Shintani ,  Masahiro Nishimura

IPC分类号： C07K14/00 ,  A61K38/16

CPC分类号： C12N5/0654 ,  A61K35/12 ,  C07K14/42 ,  C12N5/0655 ,  C12N5/0663 ,  C12N5/0664 ,  C12N2501/59

摘要： The invention provides an agent for conferring resistance comprising a lectin as an effective component, which are able to confer resistance against external stimuli to animal cells, particularly mammalian cells, and to their cultured cells and various tissues in the living bodies. The agent for conferring resistance to external stimulus according to the invention can confer to such animal cells and/or tissues resistance against mechanical stimuli and/or proteolytic reactions, and thereby enhance graft fixation of the cells and/or tissues, as well as transplant tissues obtained by culturing them.

摘要翻译： 本发明提供了赋予抗性的试剂，其包含作为有效成分的凝集素，其能够赋予动物细胞，特别是哺乳动物细胞及其培养的细胞和生物体中的各种组织对外部刺激的抵抗力。 根据本发明赋予对外部刺激的抗性的试剂可以赋予这种动物细胞和/或组织对机械刺激和/或蛋白水解反应的抗性，从而增强细胞和/或组织以及移植组织的移植物固定 通过培养获得。