公开(公告)号：US20060140974A1

公开(公告)日：2006-06-29

申请号：US11141497

申请日：2005-05-31

申请人： Yun Choe ,  Il Kang ,  Hyung Suh ,  Young Choi ,  Hee Yun ,  Kyung Kim ,  Sang Ahn ,  Ki Kim ,  Won Hwang ,  Jin Kim

发明人： Yun Choe ,  Il Kang ,  Hyung Suh ,  Young Choi ,  Hee Yun ,  Kyung Kim ,  Sang Ahn ,  Ki Kim ,  Won Hwang ,  Jin Kim

IPC分类号： A61K36/064 ,  A61K36/06

CPC分类号： A61K36/064 ,  A23L33/145 ,  A23P20/20 ,  A23V2002/00 ,  A61K36/06 ,  A23V2250/218 ,  A23V2200/31 ,  A23V2200/322 ,  A23V2200/332

摘要： A yeast extract or yeast-derived bioactive peptide having an activity of selectively inhibiting reuptake of serotonin and norepinephrine, which can be effectively used in preventing or treating various diseases related to reuptake of serotonin and norepinephrine, especially depression, anxiety, stress, fatigue and obesity are provided. Also, a yeast extract or yeast-derived bioactive peptide having activities as an anti-stress agent, an anti-fatigue agent, premenstrual syndrome (PMS) and menstrual pain relaxants, and a brain-neurotrophic factor, and a method for preparing the bioactive peptide are provided. The yeast extract or yeast-derived bioactive peptide is effective in relieving stress, nervousness, anxiety, tension, insomnia, fatigue, and imbalance in the autonomic nerve regulation. Therefore, the yeast extract or yeast-derived bioactive peptide is vailable as an anti-depression agent, an anti-anxiety agent, an anti-stress agent, an anti-fatigue agent, an anti-obesity agent, premenstrual syndrome and menstrual pain relaxants, a bain-neurotrophin, and a source of active foods having these activities.

摘要翻译： 具有选择性抑制5-羟色胺和去甲肾上腺素再摄取的活性的酵母提取物或酵母衍生生物活性肽，其可有效用于预防或治疗与再摄取5-羟色胺和去甲肾上腺素，特别是抑郁，焦虑，压力，疲劳和肥胖有关的各种疾病 被提供。 此外，具有活性作为抗应激剂，抗疲劳剂，经前综合征（PMS）和月经痛松弛剂的酵母提取物或酵母衍生的生物活性肽和脑神经营养因子，以及制备生物活性物质的方法 提供肽。 酵母提取物或酵母衍生的生物活性肽有效缓解压力，紧张，焦虑，紧张，失眠，疲劳，自主神经调节失调。 因此，酵母提取物或酵母衍生的生物活性肽作为抗抑郁剂，抗焦虑剂，抗应激剂，抗疲劳剂，抗肥胖剂，经前综合征和月经痛缓解剂 ，一种贝宁神经营养因子，以及具有这些活性的活性食物的来源。