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62 条记录 (耗时 0.044 秒)

    Method of treating or preventing hepatitis B virus
    1.
    发明申请
    Method of treating or preventing hepatitis B virus 审中-公开
    治疗或预防乙型肝炎病毒的方法

    公开(公告)号：US20050192299A1

    公开(公告)日：2005-09-01

    申请号：US10656889

    申请日：2003-09-04

    申请人： Yung-Chi Cheng ,  Chung Chu ,  Hea Kim ,  Kirupathevy Shanmuganathan

    发明人： Yung-Chi Cheng ,  Chung Chu ,  Hea Kim ,  Kirupathevy Shanmuganathan

    IPC分类号： A61K31/513 ,  A61K31/7076 ,  A61K38/21 ,  C07H17/00

    CPC分类号： C07H17/00 ,  A61K31/513 ,  A61K31/7076 ,  A61K38/212 ,  A61K2300/00

    摘要： Anti-hepatitis B virus compounds (−)3′-thia-2′,3′-dideoxycytidine, (−)5-fluoro-3′-thia-2′,3′-dideoxycytidine, (±) β-dioxolane cytosine and (−)-L-B-dioxolane cytosine. A method of treating a patient suffering from hepatitis B virus or preventing hepatitis B virus infection comprising administering to the patient an effective amount of an active compound selected from the group consisting of (a) (−)3′-thia-2′,3′-dideoxycytidine, (b) (±)3′-thia-2′3′-dideoxycytidine, (c) (−)5-fluoro-3′-thia-2′,3′-dideoxcytidine; (d) (±) 5-fluoro-3′-thia-2′3′-dideoxycytidine, (e)(±) β-dioxolane-cytosine and (f) (−)-L-β-dioxolane cytosine, or a salt or an ester thereof, either alone or in admixture within a diluent.

    摘要翻译： 抗乙型肝炎病毒化合物（ - ）3'-硫杂-2'，3'-双脱氧胞苷，（ - ）5-氟-3'-硫杂-2'，3'-双脱氧胞苷，（±）β-二氧戊环胞嘧啶和 （ - ） - LB-二氧戊环胞嘧啶。 一种治疗患有乙型肝炎病毒或预防乙型肝炎病毒感染的患者的方法，包括向患者施用有效量的选自（a）（ - ）3'-硫杂-2'，3 （b）（±）3'-thia-2'3'-双脱氧胞苷，（c）（ - ）5-氟-3'-硫杂-2'，3'-脱氧胞嘧啶; （d）（±）5-氟-3'-硫杂-2'3'-二脱氧胞苷，（e）（±）β-二氧戊环 - 胞嘧啶和（f）（ - ） - L-β-二氧戊环胞嘧啶，或 盐或其酯，单独或混合在稀释剂内。

    Casing for outdoor communication apparatus and protective device for the same
    4.
    发明授权
    Casing for outdoor communication apparatus and protective device for the same 有权
    外壳用于户外通讯设备和保护装置

    公开(公告)号：US08286816B2

    公开(公告)日：2012-10-16

    申请号：US12703411

    申请日：2010-02-10

    申请人： Yung-Chi Cheng ,  Ching-Feng Hsieh

    发明人： Yung-Chi Cheng ,  Ching-Feng Hsieh

    IPC分类号： B65D6/28

    CPC分类号： H05K5/0239

    摘要： A protective device is applicable to a casing provided with a first coupling portion and configured for use with an outdoor communication apparatus. The protective device includes a body and a shielding portion. The body is configured to shield the front of the casing and provided with a second coupling portion coupled to the first coupling portion. The shielding portion is laterally provided to the side of the body for shielding the casing sideways. Hence, the shielding portion of the protective device shields the casing from direct irradiation of sunlight, prevents the outdoor communication apparatus from being overheated, and protects the outdoor communication apparatus against rainwater and dirt. A casing configured for use with an outdoor communication apparatus and equipped with the protective device is further provided.

    摘要翻译： 保护装置适用于设置有第一联接部并配置为与室外通信装置一起使用的壳体。 保护装置包括主体和屏蔽部分。 主体被构造成屏蔽壳体的前部并且设置有联接到第一联接部分的第二联接部分。 屏蔽部分侧向设置在主体的侧面，以侧向屏蔽壳体。 因此，保护​​装置的屏蔽部遮蔽了壳体的直射照射，防止室外通信装置过热，并且保护室外通信装置免受雨水污染。 还提供了一种配置成与室外通信装置一起使用并配备有保护装置的壳体。

    Method of Treating Cancer and Other Conditions or Disease States Using L-Cytosine Nucleoside Analogs
    7.
    发明申请
    Method of Treating Cancer and Other Conditions or Disease States Using L-Cytosine Nucleoside Analogs 有权
    使用L-胞嘧啶核苷类似物治疗癌症和其他病症或疾病状态的方法

    公开(公告)号：US20090286754A1

    公开(公告)日：2009-11-19

    申请号：US11992044

    申请日：2006-11-22

    申请人： Yung-Chi Cheng

    发明人： Yung-Chi Cheng

    IPC分类号： A61K31/7068

    CPC分类号： A61K31/513 ,  A61K47/549 ,  A61K47/55

    摘要： The present invention relates to the use of the compound according to formula (I) Where S is (A) or (B); X is H or F; R1 is H, an acyl group, a C1-C20 alkyl or ether group, a phosphate, diphosphate, triphosphate or a phosphodiester group, a (C) or (D) group; Where Nu is a radical of a biologically active compound such as an anticancer, antihyperproliferative or antiviral compound such that an amino group or hydroxyl group from said biologically active agent forms a phosphate, phosphoramidate, carbonate or urethane group with the adjacent moiety; Each R8 is independently H, or a C1-C20 alkyl or ether group, preferably H or a C1-C2 alkyl group; k is 0-12, preferably, 0-2; R2 is H, an acyl group or a C1-C20 alkyl or ether group; and pharmaceutically acceptable salts, solvates or polymorphs thereof for the treatment of tumors, cancer and hyperproliferative diseases, among other conditions or disease states.

    摘要翻译： 本发明涉及式（I）化合物的用途，其中S为（A）或（B）; X为H或F; R1是H，酰基，C1-C20烷基或醚基，磷酸酯，二磷酸酯，三磷酸酯或磷酸二酯基，（C）或（D）基团; 其中Nu是生物活性化合物如抗癌，抗增白或抗病毒化合物的基团，使得所述生物活性剂的氨基或羟基与相邻部分形成磷酸酯，氨基磷酸酯，碳酸酯或氨基甲酸酯基团; 每个R 8独立地是H或C 1 -C 20烷基或醚基，优选H或C 1 -C 2烷基; k为0-12，优选为0-2; R2是H，酰基或C1-C20烷基或醚基; 和其药学上可接受的盐，溶剂合物或多晶型物，用于治疗肿瘤，癌症和过度增殖性疾病等疾病状态。

    Herbal composition PHY906 and its use in chemotherapy
    8.
    发明授权
    Herbal composition PHY906 and its use in chemotherapy 有权
    草药组合物PHY906及其在化疗中的应用

    公开(公告)号：US07534455B2

    公开(公告)日：2009-05-19

    申请号：US11100433

    申请日：2005-04-07

    申请人： Yung-Chi Cheng ,  Shwu-Huey Liu

    发明人： Yung-Chi Cheng ,  Shwu-Huey Liu

    IPC分类号： A61K36/484 ,  A61K36/725 ,  A61K36/539 ,  A61K36/65

    CPC分类号： A61K36/484 ,  A61K31/454 ,  A61K31/4745 ,  A61K31/704 ,  A61K31/7072 ,  A61K36/539 ,  A61K36/65 ,  A61K36/725 ,  A61K2300/00

    摘要： This invention provides herbal compositions useful for increasing the therapeutic index of drugs, including those used in the treatment of disease, especially viral infections and neoplasms of cancer. This invention provides methods useful for improving the quality of life of an individual undergoing chemotherapy. Furthermore, this invention improves the treatment of disease by increasing the therapeutic index of chemotherapy drugs by administering the herbal composition PHY906 to a person undergoing such chemotherapy.

    摘要翻译： 本发明提供了可用于增加药物治疗指数（包括用于治疗疾病，特别是病毒感染和癌症肿瘤）的药物组合物的草药组合物。 本发明提供了有助于改善接受化疗的个体的生活质量的方法。 此外，本发明通过将药草组合物PHY906施用于经历这种化疗的人，通过增加化疗药物的治疗指数来改善疾病的治疗。