公开(公告)号：US08900825B2

公开(公告)日：2014-12-02

申请号：US13459791

申请日：2012-04-30

Applicant: Yung-Fu Chang ,  Raghavan U. M. Palaniappan

Inventor： Yung-Fu Chang ,  Raghavan U. M. Palaniappan

IPC: G01N33/554 ,  G01N33/569 ,  C07K14/20 ,  A61K39/00

CPC classification number: G01N33/56911 ,  A61K39/00 ,  C07K14/20 ,  G01N2333/20 ,  G01N2469/10 ,  G01N2469/20 ,  Y02A50/48 ,  Y02A50/56

Abstract: The invention provides novel immunogenic proteins LigA and LigB from Leptospira for use in the development of effective vaccines and antibodies, as well as improved diagnostic methods and kits.

Abstract translation: 本发明提供了来自钩端螺旋体的新型免疫原性蛋白LigA和LigB，用于开发有效的疫苗和抗体，以及改进的诊断方法和试剂盒。

公开(公告)号：US08168207B2

公开(公告)日：2012-05-01

申请号：US12259782

申请日：2008-10-28

Applicant: Yung-Fu Chang ,  Raghavan U. M. Palaniappan

Inventor： Yung-Fu Chang ,  Raghavan U. M. Palaniappan

IPC: A61K39/002

CPC classification number: G01N33/56911 ,  A61K39/00 ,  C07K14/20 ,  G01N2333/20 ,  G01N2469/10 ,  G01N2469/20 ,  Y02A50/48 ,  Y02A50/56

Abstract: The invention provides novel immunogenic proteins LigA and LigB from Leptospira for use in the development of effective vaccines and antibodies, as well as improved diagnostic methods and kits.

Abstract translation: 本发明提供了来自钩端螺旋体的新型免疫原性蛋白LigA和LigB，用于开发有效的疫苗和抗体，以及改进的诊断方法和试剂盒。

公开(公告)号：US07655427B2

公开(公告)日：2010-02-02

申请号：US11102476

申请日：2005-04-08

Applicant: Yung-Fu Chang ,  Raghavan U. M. Palaniappan

Inventor： Yung-Fu Chang ,  Raghavan U. M. Palaniappan

IPC: G01N33/554

CPC classification number: G01N33/56911 ,  A61K39/00 ,  C07K14/20 ,  G01N2333/20 ,  G01N2469/10 ,  G01N2469/20 ,  Y02A50/48 ,  Y02A50/56

Abstract: The invention provides novel immunogenic proteins LigA and LigB from Leptospira for use in the development of effective vaccines and antibodies, as well as improved diagnostic methods and kits.

Abstract translation: 本发明提供了来自钩端螺旋体的新型免疫原性蛋白LigA和LigB，用于开发有效的疫苗和抗体，以及改进的诊断方法和试剂盒。