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公开(公告)号：US20150111826A1
公开(公告)日：2015-04-23
申请号：US14517497
申请日：2014-10-17
IPC分类号： C07K14/605
CPC分类号： C07K14/605 , A61K31/137 , A61K31/155 , A61K31/198 , A61K31/485 , A61K31/7048 , A61K38/26 , A61K38/28 , A61K45/06 , A61K2300/00
摘要： The invention provides materials and methods for the treatment of obesity and excess weight, diabetes, and other associated metabolic disorders. In particular, the invention provides novel acylated glucagon analogue peptides effective in such methods. The peptides may mediate their effect by having increased selectivity for the GLP-1 receptor as compared to human glucagon.
摘要翻译： 本发明提供了用于治疗肥胖和过量体重，糖尿病和其他相关代谢紊乱的材料和方法。 特别地，本发明提供了在这些方法中有效的新型酰化胰高血糖素类似物肽。 与人胰高血糖素相比，肽可以通过增加对GLP-1受体的选择性而介导其作用。
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公开(公告)号：US20200157168A1
公开(公告)日：2020-05-21
申请号：US16569381
申请日：2019-09-12
申请人： Zealand Pharma A/S
IPC分类号： C07K14/605 , A61K31/7048 , A61K31/485 , A61K31/198 , A61K31/155 , A61K31/137 , A61K45/06 , A61K38/28 , A61K38/26
摘要： The invention provides materials and methods for the treatment of obesity and excess weight, diabetes, and other associated metabolic disorders. In particular, the invention provides novel acylated glucagon analogue peptides effective in such methods. The peptides may mediate their effect by having increased selectivity for the GLP-1 receptor as compared to human glucagon.
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公开(公告)号：US20240141010A1
公开(公告)日：2024-05-02
申请号：US18408052
申请日：2024-01-09
申请人： Zealand Pharma A/S
IPC分类号： C07K14/605 , A61K31/137 , A61K31/155 , A61K31/198 , A61K31/485 , A61K31/7048 , A61K38/26 , A61K38/28 , A61K45/06
CPC分类号： C07K14/605 , A61K31/137 , A61K31/155 , A61K31/198 , A61K31/485 , A61K31/7048 , A61K38/26 , A61K38/28 , A61K45/06
摘要： The invention provides materials and methods for the treatment of obesity and excess weight, diabetes, and other associated metabolic disorders. In particular, the invention provides novel acylated glucagon analogue peptides effective in such methods. The peptides may mediate their effect by having increased selectivity for the GLP-1 receptor as compared to human glucagon.
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公开(公告)号：US20160009777A1
公开(公告)日：2016-01-14
申请号：US14864256
申请日：2015-09-24
申请人： ZEALAND PHARMA A/S
发明人： Jakob Lind TOLBORG , Keld FOSGERAU , Pia NØRREGAARD , Rasmus JUST , Ditte RIBER , Dieter Wolfgang HAMPRECHT , Robert AUGUSTIN , Leo THOMAS , Wolfgang RIST
IPC分类号： C07K14/605 , A61K45/06 , A61K38/26
CPC分类号： C07K14/605 , A61K38/26 , A61K45/06
摘要： The invention provides materials and methods for the treatment of obesity and excess weight, diabetes, and other associated metabolic disorders. In particular, the invention provides novel glucagon analogue peptides effective in such methods. The peptides may mediate their effect by having increased selectivity for the GLP-1 receptor as compared to human glucagon.
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公开(公告)号：US20180141990A1
公开(公告)日：2018-05-24
申请号：US15852458
申请日：2017-12-22
申请人： Zealand Pharma A/S
IPC分类号： C07K14/605 , A61K31/155 , A61K31/137 , A61K31/198 , A61K31/485 , A61K31/7048 , A61K45/06 , A61K38/26 , A61K38/28
摘要： The invention provides materials and methods for the treatment of obesity and excess weight, diabetes, and other associated metabolic disorders. In particular, the invention provides novel acylated glucagon analogue peptides effective in such methods. The peptides may mediate their effect by having increased selectivity for the GLP-1 receptor as compared to human glucagon.
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公开(公告)号：US20220073583A1
公开(公告)日：2022-03-10
申请号：US17369061
申请日：2021-07-07
申请人： Zealand Pharma A/S
IPC分类号： C07K14/605 , A61K38/26 , A61K38/28 , A61K45/06 , A61K31/137 , A61K31/155 , A61K31/198 , A61K31/485 , A61K31/7048
摘要： The invention provides materials and methods for the treatment of obesity and excess weight, diabetes, and other associated metabolic disorders. In particular, the invention provides novel acylated glucagon analogue peptides effective in such methods. The peptides may mediate their effect by having increased selectivity for the GLP-1 receptor as compared to human glucagon.
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公开(公告)号：US20190055296A1
公开(公告)日：2019-02-21
申请号：US15983822
申请日：2018-05-18
申请人： Zealand Pharma A/S
发明人： Jakob Lind TOLBORG , Keld FOSGERAU , Pia NØRREGAARD , Rasmus JUST , Ditte RIBER , Dieter Wolfgang HAMPRECHT , Robert AUGUSTIN , Leo THOMAS , Wolfgang RIST
IPC分类号： C07K14/605 , A61K38/26 , A61K45/06
摘要： The invention provides materials and methods for the treatment of obesity and excess weight, diabetes, and other associated metabolic disorders. In particular, the invention provides novel glucagon analogue peptides effective in such methods. The peptides may mediate their effect by having increased selectivity for the GLP-1 receptor as compared to human glucagon.
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