公开(公告)号：US20240016763A1

公开(公告)日：2024-01-18

申请号：US18256231

申请日：2022-03-24

申请人： ZHEJIANG NHU CO., LTD. ,  ZHEJIANG UNIVERSITY ,  XINCHANG NHU VITAMINS COMPANY LTD. ,  HEILONGJIANG NHU BIOTECHNOLOGY COMPANY LTD.

发明人： Xiaoyong ZHU ,  Jiandong LI ,  Hongyue YAN ,  Zhirong CHEN ,  Jincheng CHENG ,  Qilei ZHANG ,  Wei LI ,  Tianqi LV ,  Guilai WANG

IPC分类号： A61K31/122 ,  A23L2/52 ,  A23L29/00 ,  A23L33/10 ,  A61K8/06 ,  A61K8/35 ,  A61K8/92 ,  A61K47/44 ,  A61K47/24 ,  A61Q19/00

CPC分类号： A61K31/122 ,  A23L2/52 ,  A23L29/06 ,  A23L33/10 ,  A61K8/068 ,  A61K8/355 ,  A61K8/922 ,  A61K47/44 ,  A61K47/24 ,  A61Q19/00 ,  A61K2800/10

摘要： Provided in the present invention are a coenzyme Q10 microemulsion, a preparation method therefor and the use thereof. The coenzyme Q10 microemulsion is prepared from components comprising coenzyme Q10, a carrier oil, an anti-crystallization agent, a lipophilic emulsifier, a hydrophilic emulsifier, a co-emulsifier and water. The microemulsion has a particle size DV(90) of between 20 nm and 80 nm, and is clear, transparent, free of demulsification and high in bioavailability, can be stably stored for a long time at normal temperatures and in extreme temperature environments. In addition, the microemulsion is suitable for the pharmaceutical, cosmetic and food fields, especially for beverages, oral liquids and other products. Also provided in the present invention is a method for preparing the coenzyme Q10 microemulsion, which is simple in equipment, low in cost and easy in operation.