-
公开(公告)号：US20240174760A1
公开(公告)日：2024-05-30
申请号：US18552134
申请日：2022-03-22
发明人： Bo PENG , Jiaguo LI , Haixiang YU , Xiangzhen LIU , Yan SUN , Weimin ZHU , Qijun QIAN
IPC分类号： C07K16/28 , A61K39/00 , A61P35/00 , G01N33/574
CPC分类号： C07K16/2878 , A61P35/00 , G01N33/57492 , A61K39/00 , C07K2317/565 , C07K2317/569 , G01N2333/70575
摘要： Disclosed in the present invention is a nanobody, comprising a heavy chain variable region containing CDR1, CDR2 and/or CDR3, and having the function of recognizing and binding to BCMA. Reference can be made to the text for specific CDR sequences. Also disclosed in the present invention are a BCMA binding molecule, a composition comprising the nanobody or BCMA binding molecule, a BCMA detection agent, and an application of the nanobody, the BCMA binding molecule, or the composition in preparation of a drug for treating a BCMA related disease. The nanobody, BCMA binding molecule, and composition in the present invention can recognize and bind to BCMA, and have potential utility for treatment of BCMA related diseases.
-
公开(公告)号：US20240190986A1
公开(公告)日：2024-06-13
申请号：US18269945
申请日：2021-12-27
发明人： Jiaguo LI , Haixiang YU , Xiangzhen LIU , Weimin ZHU , Yan SUN , Na DING , Qijun QIAN
IPC分类号： C07K16/30 , G01N33/574
CPC分类号： C07K16/30 , G01N33/57484 , C07K2317/14 , C07K2317/22 , C07K2317/24 , C07K2317/52 , C07K2317/524 , C07K2317/526 , C07K2317/565 , C07K2317/567 , C07K2317/569 , C07K2317/92
摘要： The present invention provides a mesothelin binding molecule, comprising an anti-mesothelin single domain antibody. Complementarity determining regions (CDR) of the single domain antibody comprise CDR1 shown in SEQ ID NO: 1, CDR2 shown in SEQ ID NO: 2, and CDR3 shown in SEQ ID NO: 3.
-
搜索结果
2 条记录 (耗时 0.011 秒)
