专利检索 ap:("Zibo Li" OR "Francois P. Gabbai" OR "Peter S. Conti" OR "Todd W. Hudnall" OR "Tzu-Pin Lin" OR "Shuanglong Liu" OR "Chiun-Wei Huang") AND inv:"Chiun-Wei Huang" 第 1 页

1.

发明授权
Boron-based dual imaging probes, compositions and methods for rapid aqueous F-18 labeling, and imaging methods using same 有权

公开(公告)号：US09987380B2

公开(公告)日：2018-06-05

申请号：US13549309

申请日：2012-07-13

申请人： Zibo Li , Francois P. Gabbai , Peter S. Conti , Todd W. Hudnall , Tzu-Pin Lin , Shuanglong Liu , Chiun-Wei Huang

发明人： Zibo Li , Francois P. Gabbai , Peter S. Conti , Todd W. Hudnall , Tzu-Pin Lin , Shuanglong Liu , Chiun-Wei Huang

IPC分类号： A61K51/00 , A61M36/14 , A61K51/04 , A61K49/00 , C07F5/02

CPC分类号： A61K51/0446 , A61K49/0002 , A61K49/0021 , A61K51/00 , A61K51/0423 , A61K51/0455 , C07F5/022

摘要： A composition useful as a PET and/or fluorescence imaging probe a compound a compound of Formula I, including salts, hydrates and solvates thereof: wherein R1-R7 may be independently selected from hydrogen, halogen, hydroxy, alkoxy, nitro, substituted and unsubstituted amino, cycloalkyl, carboxy, carboxylic acids and esters thereof, cyano, haloalkyl, aryl, X is selected from the group consisting of C and N; and A is selected of hydrogen, halogen, hydroxy, alkoxy, nitro, substituted and unsubstituted amino, alkyl, cycloalkyl, carboxy, carboxylic acids and esters thereof, cyano, haloalkyl, aryl, including phenyl and aminophenyl, and heteroaryl.