公开(公告)号：US20210355086A1

公开(公告)日：2021-11-18

申请号：US17278385

申请日：2019-09-23

申请人： Zoetis Services LLC

发明人： Randall Lee DeJong ,  Gregory Lee Karrick ,  Timothy Lee Stuk

IPC分类号： C07D213/71 ,  B01J31/04 ,  B01J31/24

摘要： The present invention provides a novel process for preparing a diastereomeric mixture of the phenicol of Formula (1), its use for the treatment of bacterial infections in animals, and veterinary compositions containing the Formula (1) compound, diastereomers thereof, and veterinary acceptable salts thereof.

公开(公告)号：US09926327B2

公开(公告)日：2018-03-27

申请号：US15426292

申请日：2017-02-07

申请人： Zoetis Services LLC

发明人： Timothy Lee Stuk ,  Denis Billen ,  Valerie Sue Westrick ,  Vageesha Warnajith Liyana Gunawardana

IPC分类号： C07D487/04 ,  C07C303/22 ,  C07C303/32 ,  C07C309/19 ,  C07C309/24 ,  C07C309/30

CPC分类号： C07D487/04 ,  C07C303/22 ,  C07C303/32 ,  C07C309/19 ,  C07C309/24 ,  C07C309/30

摘要： Described herein are improved processes for the preparation of the 7H-pyrrolo[2,3-d]pyrimidine compound, N-methyl-1-{trans-4-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]cyclohexyl}-methanesulfonamide, intermediates thereof, and veterinary acceptable salts thereof.

公开(公告)号：US20170233397A1

公开(公告)日：2017-08-17

申请号：US15426292

申请日：2017-02-07

申请人： Zoetis Services LLC

发明人： Timothy Lee Stuk ,  Denis Billen ,  Valerie Sue Westrick ,  Vageesha Warnajith Liyana Gunawardana

IPC分类号： C07D487/04 ,  C07C309/19 ,  C07C309/24 ,  C07C303/32 ,  C07C303/22

CPC分类号： C07D487/04 ,  C07C303/22 ,  C07C303/32 ,  C07C309/19 ,  C07C309/24 ,  C07C309/30

摘要： Described herein are improved processes for the preparation of the 7H-pyrrolo[2,3-d]pyrimidine compound, N-methyl-1-{trans-4-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]cyclohexyl}-methanesulfonamide, intermediates thereof, and veterinary acceptable salts thereof.