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公开(公告)号:US07241754B2
公开(公告)日:2007-07-10
申请号:US10868724
申请日:2004-06-14
申请人: Zong-Qiang Tian , Robert McDaniel , David C. Myles , Kedar Gautam Patel , Misty Piagentini , Zhan Wang
发明人: Zong-Qiang Tian , Robert McDaniel , David C. Myles , Kedar Gautam Patel , Misty Piagentini , Zhan Wang
IPC分类号: C07D225/04 , C07D225/06 , A61K31/395 , A61K31/33 , A61K31/40
CPC分类号: C07D225/06 , C07D491/04
摘要: 2-Desmethyl ansamycins having a structure according to formula I, where R1, R2, R3, R4, R5 and R6 are as defined herein, and other 2-desmethyl ansamycins are useful as antiproliferative agents
摘要翻译: 具有式I结构的2-去甲基安沙霉素,其中R 1,R 2,R 3,R 4, 其中R 5,R 5和R 6如本文所定义,而其它2-去甲基安沙霉素可用作抗增殖剂
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公开(公告)号:US20050026894A1
公开(公告)日:2005-02-03
申请号:US10868724
申请日:2004-06-14
申请人: Zong-Qiang Tian , Robert McDaniel , David Myles , Kedar Patel , Misty Piagentini , Zhan Wang
发明人: Zong-Qiang Tian , Robert McDaniel , David Myles , Kedar Patel , Misty Piagentini , Zhan Wang
IPC分类号: A61K20060101 , A61K31/33 , A61P35/00 , C07D507/00 , C12N1/21
CPC分类号: C07D225/06 , C07D491/04
摘要: 2-Desmethyl ansamycins having a structure according to formula I, where R1, R2, R3, R4, R5 and R6 are as defined herein, and other 2-desmethyl ansamycins are useful as antiproliferative agents.
摘要翻译: 具有式I结构的2-去甲基安沙霉素,其中R 1,R 2,R 3,R 4,R 5和R 6如本文所定义,其它2 β-甲基安沙霉素可用作抗增殖剂。
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