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公开(公告)号:US20150266963A1
公开(公告)日:2015-09-24
申请号:US14626038
申请日:2015-02-19
申请人: arGEN-X N.V.
发明人: Karen SILENCE , Peter ULRICHTS , Johannes Joseph Wilhelmus DE HAARD , Torsten DREIER , Michael John Scott SAUNDERS , Harald WAJANT , Sofie Maria Elvire GABRIELS , Mahan MOSHIR
IPC分类号: C07K16/28
CPC分类号: C07K16/2875 , A61K2039/505 , C07K16/2878 , C07K2317/22 , C07K2317/24 , C07K2317/34 , C07K2317/41 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/73 , C07K2317/732 , C07K2317/734 , C07K2317/76 , C07K2317/77 , C07K2317/92 , C07K2317/94
摘要: The present invention relates to antibodies and antigen binding fragments thereof which bind to the human CD70 protein with high affinity and display potent inhibition of tumour cell growth.
摘要翻译: 本发明涉及以高亲和力结合人CD70蛋白的抗体及其抗原结合片段,并显示对肿瘤细胞生长的有效抑制。
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公开(公告)号:US20170369581A9
公开(公告)日:2017-12-28
申请号:US14626038
申请日:2015-02-19
申请人: arGEN-X N.V.
发明人: Karen SILENCE , Peter ULRICHTS , Johannes Joseph Wilhelmus DE HAARD , Torsten DREIER , Michael John Scott SAUNDERS , Harald WAJANT , Sofie Maria Elvire GABRIELS , Mahan MOSHIR
CPC分类号: C07K16/2875 , A61K2039/505 , C07K16/2878 , C07K2317/22 , C07K2317/24 , C07K2317/34 , C07K2317/41 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/73 , C07K2317/732 , C07K2317/734 , C07K2317/76 , C07K2317/77 , C07K2317/92 , C07K2317/94
摘要: The present invention relates to antibodies and antigen binding fragments thereof which bind to the human CD70 protein with high affinity and display potent inhibition of tumour cell growth.
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