公开(公告)号：US20030166904A1

公开(公告)日：2003-09-04

申请号：US10178194

申请日：2002-06-21

申请人： deCODE genetics ehf.

发明人： Berglind Ran Olafsdottir ,  Jeffrey Gulcher

IPC分类号： A61K048/00 ,  C12Q001/68 ,  C07H021/04

CPC分类号： C07K14/70571 ,  A61K38/00

摘要： The gene for hypocretin (orexin) receptor 2 (HCRTR2), which is associated with narcolepsy, is disclosed. Also described are methods of diagnosis of narcolepsy, pharmaceutical compositions comprising nucleic acids comprising the HCRTR2 gene, as well as methods of therapy of narcolepsy.

公开(公告)号：US20020146719A1

公开(公告)日：2002-10-10

申请号：US09961848

申请日：2001-09-24

申请人： deCODE genetics ehf

发明人： Berglind Ran Olafsdottir ,  Jeffrey Gulcher

IPC分类号： A61K048/00 ,  C12Q001/68

CPC分类号： C07K14/70571 ,  A61K48/00 ,  C12Q1/6883 ,  C12Q2600/118 ,  C12Q2600/156

摘要： The gene for hypocretin (orexin) receptor 1 (HCRTR1), which is associated with narcolepsy, is disclosed. Also described are methods of diagnosis of narcolepsy, pharmaceutical compositions comprising nucleic acids comprising the HCRTR1 gene, as well as methods of therapy of narcolepsy.

摘要翻译： 公开了与发作性睡病有关的下丘脑素（食欲肽）受体1（HCRTR1）的基因。 还描述了发作性睡病的诊断方法，包含包含HCRTR1基因的核酸的药物组合物以及发作性睡病的治疗方法。