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公开(公告)号:US20210261670A1
公开(公告)日:2021-08-26
申请号:US17163246
申请日:2021-01-29
发明人: SOMDUTTA ROY , LAURA SAUNDERS , CASEY FRANKLIN , KEVIN MARTINEZ , SARAH FONG , ZHAO HUANG , SILVIA JUAREZ , ALINA HE , KATHRYN A. LOVING , SANDRO VIVONA
IPC分类号: C07K16/28 , C07K16/32 , A61K47/68 , A61K39/395 , A61P35/00
摘要: Provided are novel anti-BMPR1B antibodies and antibody drug conjugates, and methods of using such anti-BMPR1B antibodies and antibody drug conjugates to treat cancer.
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公开(公告)号:US11077203B2
公开(公告)日:2021-08-03
申请号:US16908645
申请日:2020-06-22
发明人: David Liu , Julia Gavrilyuk , Alexander Schammel
摘要: Provided are novel anti-SEZ6 antibodies and antibody drug conjugates, and methods of using such anti-SEZ6 antibodies and antibody drug conjugates to treat cancer.
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公开(公告)号:US10308721B2
公开(公告)日:2019-06-04
申请号:US15120499
申请日:2015-02-23
IPC分类号: A61K39/395 , C07K16/18 , C07K16/28 , C07K16/30 , G01N33/574 , C12Q1/6886 , A61K47/68 , A61K39/00
摘要: Anti-DLL3 antibodies and antibody drug conjugates for use in the diagnosis and treatment of melanoma.
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公开(公告)号:US20190077876A1
公开(公告)日:2019-03-14
申请号:US16105651
申请日:2018-08-20
发明人: Marianne SANTAGUIDA , Monette AUJAY , Laura SAUNDERS , David LIU , Orit FOORD , Robert A. STULL , Paul Anthony ESCARPE
摘要: Provided herein are novel anti-CLDN antibodies and antibody drug conjugates (ADC), including derivatives thereof, and methods of using the same to treat proliferative disorders.
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公开(公告)号:US20180346565A1
公开(公告)日:2018-12-06
申请号:US16049349
申请日:2018-07-30
发明人: WILLIAM ROBERT ARATHOON , ISHAI PADAWER , LUIS ANTONIO CANO , VIKRAM NATWARSINHJI SISODIYA , KARTHIK NARAYAN MANI , DAVID LIU
CPC分类号: C07K16/28 , A61K47/6803 , A61K47/6811 , A61K47/6843 , A61K47/6849 , A61K2039/505 , C07K16/18 , C07K16/2896 , C07K16/30 , C07K2317/24 , C07K2317/53 , C07K2317/73
摘要: Provided are novel antibody drug conjugates (ADCs), and methods of using such ADCs to treat proliferative disorders.
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公开(公告)号:US20180318441A1
公开(公告)日:2018-11-08
申请号:US15946459
申请日:2018-04-05
IPC分类号: A61K47/68 , A61K31/5517 , A61K45/06 , C07K16/30
摘要: Provided are novel antibody drug conjugates (ADCs), and methods of using such ADCs to treat proliferative disorders.
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公开(公告)号:US20180243435A1
公开(公告)日:2018-08-30
申请号:US15753509
申请日:2016-08-19
发明人: SCOTT J. DYLLA , BRIAN SLINGERLAND , TAE HAN , JOHN PEATTIE , HOLGER KARSUNKY , WADE C. ANDERSON
CPC分类号: A61K47/6849 , A61K39/39591 , A61K47/6803 , A61K2039/505 , A61K2039/507 , A61P35/00 , C07K16/18 , C07K16/28 , C07K16/2818 , C07K2317/24 , C07K2317/34
摘要: Provided are novel anti-DLL3 antibodies and antibody drug conjugates, and methods of using such anti-DLL3 antibodies and antibody drug conjugates to treat cancer.
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公开(公告)号:US09937268B2
公开(公告)日:2018-04-10
申请号:US15694629
申请日:2017-09-01
发明人: Robert A. Stull , Laura Saunders , Scott J. Dylla , Orit Foord , David Liu , Michael Torgov , Hui Shao
IPC分类号: A61K39/395 , C07K16/18 , C12P21/08 , A61K47/68 , C07D487/04 , C07K16/30 , A61K31/551 , A61K51/10 , C07K16/28 , G01N33/574 , A61K31/5517 , A61K45/06 , A61K39/00
CPC分类号: A61K47/6803 , A61K31/551 , A61K31/5517 , A61K39/3955 , A61K45/06 , A61K47/48384 , A61K47/48407 , A61K47/48469 , A61K47/48538 , A61K47/48561 , A61K47/48592 , A61K47/48638 , A61K47/48715 , A61K47/48723 , A61K47/6809 , A61K47/6811 , A61K47/6813 , A61K47/6825 , A61K47/6829 , A61K47/6843 , A61K47/6849 , A61K47/6851 , A61K47/6855 , A61K47/6857 , A61K47/6859 , A61K47/6861 , A61K47/6867 , A61K47/6869 , A61K47/6889 , A61K47/6891 , A61K51/1096 , A61K2039/505 , A61K2039/572 , C07D487/04 , C07D487/16 , C07K16/18 , C07K16/28 , C07K16/2809 , C07K16/30 , C07K16/3023 , C07K16/3069 , C07K2317/20 , C07K2317/21 , C07K2317/24 , C07K2317/31 , C07K2317/33 , C07K2317/34 , C07K2317/35 , C07K2317/53 , C07K2317/54 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/622 , C07K2317/626 , C07K2317/70 , C07K2317/73 , C07K2317/732 , C07K2317/76 , C07K2317/77 , C07K2317/92 , C07K2319/30 , G01N33/57423 , G01N33/57492 , G01N2333/70596
摘要: Novel modulators, including antibodies and derivatives thereof, and methods of using such modulators to treat proliferative disorders are provided.
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公开(公告)号:US09931420B2
公开(公告)日:2018-04-03
申请号:US15694602
申请日:2017-09-01
发明人: Robert A. Stull , Laura Saunders , Scott J. Dylla , Orit Foord , David Liu , Michael Torgov , Hui Shao
IPC分类号: A61K39/395 , C07K16/18 , C12P21/08 , A61K47/68 , C07K16/30 , A61K31/551 , A61K51/10 , C07K16/28 , G01N33/574 , A61K31/5517 , A61K45/06 , C07D487/04 , A61K39/00
CPC分类号: A61K47/6803 , A61K31/551 , A61K31/5517 , A61K39/3955 , A61K45/06 , A61K47/48384 , A61K47/48407 , A61K47/48469 , A61K47/48538 , A61K47/48561 , A61K47/48592 , A61K47/48638 , A61K47/48715 , A61K47/48723 , A61K47/6809 , A61K47/6811 , A61K47/6813 , A61K47/6825 , A61K47/6829 , A61K47/6843 , A61K47/6849 , A61K47/6851 , A61K47/6855 , A61K47/6857 , A61K47/6859 , A61K47/6861 , A61K47/6867 , A61K47/6869 , A61K47/6889 , A61K47/6891 , A61K51/1096 , A61K2039/505 , A61K2039/572 , C07D487/04 , C07D487/16 , C07K16/18 , C07K16/28 , C07K16/2809 , C07K16/30 , C07K16/3023 , C07K16/3069 , C07K2317/20 , C07K2317/21 , C07K2317/24 , C07K2317/31 , C07K2317/33 , C07K2317/34 , C07K2317/35 , C07K2317/53 , C07K2317/54 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/622 , C07K2317/626 , C07K2317/70 , C07K2317/73 , C07K2317/732 , C07K2317/76 , C07K2317/77 , C07K2317/92 , C07K2319/30 , G01N33/57423 , G01N33/57492 , G01N2333/70596
摘要: Novel modulators, including antibodies and derivatives thereof, and methods of using such modulators to treat proliferative disorders are provided.
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公开(公告)号:US20180044415A1
公开(公告)日:2018-02-15
申请号:US15553102
申请日:2016-02-23
IPC分类号: C07K16/28 , C12N5/0783 , A61K35/17 , C12N15/86 , C07K14/725 , C07K14/705
CPC分类号: C07K16/28 , A61K35/17 , A61K38/00 , C07K14/7051 , C07K14/70578 , C07K16/2815 , C07K2317/24 , C07K2317/56 , C07K2317/622 , C07K2319/02 , C07K2319/03 , C07K2319/74 , C12N5/0638 , C12N15/86 , C12N2510/00 , C12N2740/15043
摘要: Provided herein are novel anti-DLL3 chimeric antigen receptors and methods of using the same to treat proliferative disorders.
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