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    Systems and methods for shrinking and/or securing cardiovascular tissue
    1.
    发明授权
    Systems and methods for shrinking and/or securing cardiovascular tissue 失效
    用于收缩和/或确保心血管组织的系统和方法

    公开(公告)号：US07473252B2

    公开(公告)日：2009-01-06

    申请号：US11243324

    申请日：2005-10-04

    申请人： Robert L. Barry

    发明人： Robert L. Barry

    IPC分类号： A61B18/18 ,  A61N1/05

    CPC分类号： A61B18/1492 ,  A61B2017/00575 ,  A61B2018/00351

    摘要： Systems and methods for treating cardiac tissue are disclosed. A method in accordance with one embodiment of the invention is directed to treating cardiac tissue that includes a primum, a secundum adjacent to the primum, and a patent foramen ovale (PFO). The method can include shrinking the primum at a first location spaced apart from the PFO, and at least partially sealing the PFO by applying energy at a second location at least closer to the PFO than the first location. A variety of techniques, including vacuum, mechanical, chemical, RF energy and ultrasound can be used to shrink the primum. In at least some embodiments, shrinking the primum can be performed independently of whether a PFO is also sealed, for example, if the patient receiving the treatment does not have a PFO.

    摘要翻译： 公开了用于治疗心脏组织的系统和方法。 根据本发明的一个实施方案的方法涉及治疗心脏组织，所述心脏组织包括与所述原发性邻近的最佳，间隔和卵圆孔卵孔（PFO）。 该方法可以包括在与PFO间隔开的第一位置处收缩最佳值，并且至少部分地通过在比第一位置更靠近PFO的第二位置施加能量来部分地密封PFO。 可以使用各种技术，包括真空，机械，化学，射频能量和超声波来收缩最佳。 在至少一些实施例中，可以独立于PFO是否也被密封来执行最小化的收缩，例如，如果接受治疗的患者没有PFO。

    Systems and methods for securing cardiovascular tissue
    2.
    发明授权
    Systems and methods for securing cardiovascular tissue 失效
    用于确保心血管组织的系统和方法

    公开(公告)号：US07257450B2

    公开(公告)日：2007-08-14

    申请号：US11004634

    申请日：2004-12-02

    申请人： David C. Auth ,  Dean T. Corcoran ,  Mark A. Tempel ,  Joseph E. Eichinger

    发明人： David C. Auth ,  Dean T. Corcoran ,  Mark A. Tempel ,  Joseph E. Eichinger

    IPC分类号： A61N1/05 ,  A61N1/18

    CPC分类号： A61B18/1492 ,  A61B2017/00575 ,  A61B2018/00291 ,  A61B2018/00351 ,  A61B2018/00619 ,  A61N1/06 ,  A61N1/403

    摘要： Methods and systems for securing tissues, e.g., cardiovascular tissues, are disclosed. A method in accordance with one embodiment of the invention includes inserting a portion of a catheter into an opening between a first portion of cardiovascular tissue and a second portion of cardiovascular tissue. The method can further include drawing the first and second portions of the cardiovascular tissue into contact with each other by drawing a vacuum in a region adjacent to the first and second portions of cardiovascular tissue via the catheter while the catheter is positioned between the first and second portions. The tissue portions can be fused by heating the tissue from within the opening, e.g., via radio frequency energy. This technique, and associated catheter system, can be used to close a patent foramen ovale or other openings in cardiovascular tissue.

    摘要翻译： 公开了用于确保组织例如心血管组织的方法和系统。 根据本发明的一个实施例的方法包括将导管的一部分插入心血管组织的第一部分和心血管组织的第二部分之间的开口中。 该方法可以进一步包括通过在导管位于第一和第二部分之间的同时在与心血管组织的第一和第二部分相邻的区域中抽取真空而将心血管组织的第一和第二部分相互接触 部分。 组织部分可以通过例如通过射频能量从开口内加热组织来融合。 该技术和相关的导管系统可用于闭合心脏组织中的卵孔或其他开口的专利。

    Tissue-penetrating guidewires with shaped tips, and associated systems and methods
    4.
    发明授权
    Tissue-penetrating guidewires with shaped tips, and associated systems and methods 失效
    具有形状尖端的组织穿透导丝，以及相关的系统和方法

    公开(公告)号：US08308723B2

    公开(公告)日：2012-11-13

    申请号：US12576928

    申请日：2009-10-09

    申请人： Larry B. Kulesa ,  David C. Auth ,  Ryan E. Kaveckis

    发明人： Larry B. Kulesa ,  David C. Auth ,  Ryan E. Kaveckis

    IPC分类号： A61B18/14

    CPC分类号： A61B18/1492 ,  A61B2018/00351 ,  A61B2018/00357 ,  A61B2018/0063 ,  Y10T29/49002

    摘要： Tissue-penetrating guidewires with shaped tips, and associated systems and methods are disclosed. A patient treatment system in accordance with one embodiment of the disclosure includes a tissue-penetrating guidewire that in turn includes a flexible segment having a distal portion and a proximal portion. The flexible segment is elongated along an elongation axis. A penetrating member is positioned at the distal portion and includes at least one blade segment having a tapered outer peripheral surface and an adjacent generally sharp edge. The blade segment extends to a distal end of the penetrating member to form a generally blunt tip. In operation, the guidewire can be connected to an electrical current source to deliver high frequency current to the penetrating member.

    摘要翻译： 具有成形尖端的组织穿透导丝以及相关系统和方法被公开。 根据本公开的一个实施例的患者治疗系统包括组织穿透导丝，该导丝又包括具有远端部分和近端部分的柔性部分。 柔性段沿伸长轴伸长。 穿透构件定位在远侧部分并且包括至少一个具有锥形外周表面和相邻的大致锋利边缘的刀片段。 刀片段延伸到穿透构件的远端以形成通常钝的末端。 在操作中，导丝可以连接到电流源以将高频电流传送到穿透构件。

    Systems and Methods for Controlling Patient Catheters
    5.
    发明申请
    Systems and Methods for Controlling Patient Catheters 审中-公开
    用于控制患者导管的系统和方法

    公开(公告)号：US20100087811A1

    公开(公告)日：2010-04-08

    申请号：US12246349

    申请日：2008-10-06

    申请人： David A. Herrin ,  Mark A. Tempel ,  Neil Mcilvaine

    发明人： David A. Herrin ,  Mark A. Tempel ,  Neil Mcilvaine

    IPC分类号： A61B18/18 ,  A61M25/092

    CPC分类号： A61B17/0057 ,  A61B18/1492 ,  A61B2017/00575 ,  A61B2018/00214 ,  A61B2018/00898 ,  A61B2018/1475

    摘要： Systems and methods for controlling patient catheters are disclosed. A system in accordance with a particular embodiment includes a catheter carrying multiple active elements, and a controller connected to the catheter. The controller can include a housing having directional indicators, and multiple control elements coupled to the multiple active elements. Individual control elements can be moveable relative to the housing to control the motion of the active elements, and the multiple control elements can be positioned so that manipulation of the multiple control elements in a first order that is clockwise or counterclockwise as identified by the directional indicators moves the multiple active elements in a first manner, and manipulation of the multiple control elements in a second order opposite the first order moves the multiple active elements in a second manner opposite the first manner.

    摘要翻译： 公开了用于控制患者导管的系统和方法。 根据特定实施例的系统包括承载多个有源元件的导管和连接到导管的控制器。 控制器可以包括具有方向指示器的壳体和耦合到多个有源元件的多个控制元件。 单独的控制元件可以相对于壳体移动以控制有源元件的运动，并且可以将多个控制元件定位成使得以由方向指示器识别的顺时针或逆时针方向的第一顺序操纵多个控制元件 以第一种方式移动多个活动元件，并且以与第一顺序相反的第二顺序操纵多个控制元件以与第一种方式相反的第二种方式移动多个活动元件。

    Systems and Methods for Transeptal Cardiac Procedures, Including Separable Guidewires
    6.
    发明申请
    Systems and Methods for Transeptal Cardiac Procedures, Including Separable Guidewires 失效
    经心脏手术的系统和方法，包括可分离的导丝

    公开(公告)号：US20090131925A1

    公开(公告)日：2009-05-21

    申请号：US12246369

    申请日：2008-10-06

    申请人： Mark A. Tempel ,  David A. Herrin

    发明人： Mark A. Tempel ,  David A. Herrin

    IPC分类号： A61B18/18 ,  A61B17/03

    CPC分类号： A61B18/1492 ,  A61B17/0057 ,  A61B2017/00575 ,  A61B2017/22038 ,  A61B2018/00208 ,  A61B2018/00214 ,  A61B2018/00279 ,  A61B2018/00285 ,  A61B2018/00351 ,  A61B2018/00898 ,  A61B2018/144

    摘要： Systems and methods for transeptal cardiac procedures are disclosed. A patient treatment device in accordance with a particular embodiment includes an elongated first intravenous guidewire that includes a first branch and a second branch fixably secured relative to the first branch at a first location. The device can further include an elongated second intravenous guidewire that is movable relative to at least one of the first and second branches between a first position in which the first and second branches are releasably secured relative to each other by the second guidewire at a second location, and a second position in which the first and second branches are separated from each other at the second location.

    摘要翻译： 公开了用于经心脏心脏手术的系统和方法。 根据特定实施例的患者治疗装置包括细长的第一静脉导丝，其包括在第一位置处相对于第一分支可固定地固定的第一分支和第二分支。 所述装置还可以包括细长的第二静脉导丝，其可相对于所述第一和第二分支中的至少一个在第一位置和第二位置之间移动，所述第一位置在所述第一位置和所述第一位置之间， 以及第二位置，其中第一和第二分支在第二位置彼此分离。

    Systems and methods for directing valves that control a vacuum applied to a patient
    7.
    发明申请
    Systems and methods for directing valves that control a vacuum applied to a patient 审中-公开
    用于引导控制施加到患者的真空的阀的系统和方法

    公开(公告)号：US20070123824A1

    公开(公告)日：2007-05-31

    申请号：US11582253

    申请日：2006-10-16

    申请人： Ryan Kaveckis

    发明人： Ryan Kaveckis

    IPC分类号： A61M1/00

    CPC分类号： A61B17/0057 ,  A61B18/1492 ,  A61B2017/00575 ,  A61B2017/22038 ,  A61B2018/00232 ,  A61B2018/00291 ,  A61B2018/00351 ,  A61B2018/0063 ,  A61B2018/00702 ,  A61B2018/00875 ,  A61B2217/005 ,  A61M1/0049

    摘要： Systems and methods for directing valves that control a vacuum applied to a patient are disclosed. A method in accordance with one embodiment includes receiving a first input to apply vacuum to an orifice of a device positioned within a patient, and in response to the first input, automatically directing a first valve coupled between the orifice and a vacuum source to move from a closed state to an open state. The method can further include receiving a second input to cease applying the vacuum to the orifice, and in response to the second input, automatically directing the first valve to move from the open state to the closed state, automatically directing a second valve coupled between the orifice and atmospheric pressure to move from a closed state to an open state, and automatically directing the second valve to move back from the open state to the closed state.

    摘要翻译： 公开了用于引导控制施加于患者的真空的阀的系统和方法。 根据一个实施例的方法包括接收第一输入以对定位在患者体内的装置的孔施加真空，并且响应于第一输入，自动引导联接在孔和真空源之间的第一阀从 关闭状态为开放状态。 该方法还可以包括接收第二输入以停止向孔口施加真空，并且响应于第二输入，自动地引导第一阀从打开状态移动到闭合状态，自动引导连接在孔之间的第二阀 孔口和大气压力从关闭状态移动到打开状态，并且自动地引导第二阀从打开状态回到关闭状态。

    Systems and Methods for Transeptal Cardiac Procedures, Including Tissue Compression Devices and Methods
    9.
    发明申请
    Systems and Methods for Transeptal Cardiac Procedures, Including Tissue Compression Devices and Methods 审中-公开
    包括组织压缩装置和方法的心脏过渡系统和方法

    公开(公告)号：US20090093803A1

    公开(公告)日：2009-04-09

    申请号：US12246366

    申请日：2008-10-06

    申请人： David A. Herrin

    发明人： David A. Herrin

    IPC分类号： A61B18/18 ,  A61B18/14

    CPC分类号： A61B18/1492 ,  A61B17/0057 ,  A61B2017/00575 ,  A61B2017/22038 ,  A61B2018/00208 ,  A61B2018/00214 ,  A61B2018/00279 ,  A61B2018/00285 ,  A61B2018/00351 ,  A61B2018/00898 ,  A61B2018/144

    摘要： Systems and methods for transeptal cardiac procedures are disclosed. A patient treatment system in accordance with a particular embodiment includes a catheter, a tissue penetration device carried by and deployable from the catheter, an energy delivery device carried by an deployable from the catheter, a backstop surface carried by the catheter, and a flexible, resilient tissue compression device. The tissue compression device can be coupled between the energy delivery device and the catheter and can be changeable between a first configuration in which the energy delivery device applies a first force to the backstop surface via intervening tissue, and a second configuration in which the energy delivery device applies no force or a second force less than the first force into the backstop surface via intervening tissue.

    摘要翻译： 公开了用于经心脏心脏手术的系统和方法。 根据特定实施例的患者治疗系统包括导管，由导管携带和可展开的组织穿透装置，由导管可展开的能量递送装置，由导管承载的止回表面，以及柔性的， 弹性组织压缩装置。 组织压缩装置可以联接在能量输送装置和导管之间，并且可以在其中能量输送装置通过介入组织向止回表面施加第一力的第一构型和第二构型之间改变，其中能量输送 装置通过中间组织不施加小于第一力的力或第二力施加到止回表面。