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1.发明授权Analogues of camptothecin, their use as medicaments and the pharmaceutical compositions containing them 失效喜树碱的类似物，它们作为药物的用途以及含有他们的药物组合物公开(公告)号：US07053102B2
公开(公告)日：2006-05-30
申请号：US10862245
申请日：2004-06-07
申请人： Dennis Bigg , Olivier Lavergne , Francesc Pla Rodas , Jacques Pommier , Gerard Ulibarri , Jerry Harnett , Alain Rolland , Anne-Marie Liberatore , Christophe Lanco , Jean-Bernard Cazaux , Christine Le Breton , Eric Manginot
发明人： Dennis Bigg , Olivier Lavergne , Francesc Pla Rodas , Jacques Pommier , Gerard Ulibarri , Jerry Harnett , Alain Rolland , Anne-Marie Liberatore , Christophe Lanco , Jean-Bernard Cazaux , Christine Le Breton , Eric Manginot
IPC分类号： A61K31/47
CPC分类号： C07D213/64 , C07D213/61 , C07D471/14 , C07D491/04
摘要： Compositions for treating cancer comprising an amount of a camptothecin with a 7-ring β-hydroxy lactone ring of the formula wherein the substituents are defined as in the specification sufficient to treat cancer.
摘要翻译： 用于治疗癌症的组合物，其包含一定量的具有下式的7-环β-羟基内酯环的喜树碱，其中取代基如本说明书中所定义，足以治疗癌症。
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2.发明申请New analogues of camptothecin, their use as medicaments and the pharmaceutical compositions containing them 失效喜树碱的新类似物，它们作为药物的用途和含有他们的药物组合物公开(公告)号：US20040254163A1
公开(公告)日：2004-12-16
申请号：US10862245
申请日：2004-06-07
发明人： Dennis Bigg , Olivier Lavergne , Francesc Pla Rodas , Jacques Pommier , Gerard Ulibarri , Jerry Harnett , Alain Rolland , Anne-Marie Liberatore , Christophe Lanco , Jean-Bernard Cazaux , Christine Le Breton , Eric Manginot
IPC分类号： C07D491/14
CPC分类号： C07D213/64 , C07D213/61 , C07D471/14 , C07D491/04
摘要： Compositions for treating cancer comprising an amount of a camptothecin with a 7-ring null-hydroxy lactone ring of the formula 1 wherein the substituents are defined as in the specification sufficient to treat cancer.
摘要翻译： 用于治疗癌症的组合物，其包含一定量的具有下式的7-环β-羟基内酯环的喜树碱，其中取代基如本说明书中所定义，足以治疗癌症。
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3.发明申请New analogues of camptothecin, their use as medicaments and the pharmaceutical compositions containing them 有权喜树碱的新类似物，它们作为药物的用途和含有他们的药物组合物公开(公告)号：US20050038064A1
公开(公告)日：2005-02-17
申请号：US10930622
申请日：2004-08-31
申请人： Dennis Bigg , Olivier Lavergne , Francesc Rodas , Jacques Pommier , Gerard Ulibarri , Jerry Harnett , Alain Rolland , Anne-Marie Liberatore , Christophe Lanco , Jean-Bernard Cazaux , Christine Le Breton , Eric Manginot
发明人： Dennis Bigg , Olivier Lavergne , Francesc Rodas , Jacques Pommier , Gerard Ulibarri , Jerry Harnett , Alain Rolland , Anne-Marie Liberatore , Christophe Lanco , Jean-Bernard Cazaux , Christine Le Breton , Eric Manginot
IPC分类号： C07D213/61 , C07D213/64 , C07D471/14 , C07D491/04 , C07D491/22 , C07D498/22
CPC分类号： C07D213/64 , C07D213/61 , C07D471/14 , C07D491/04
摘要： A compound of the formula wherein the substituents are defined as in the specification which compounds are useful in the treatment of cancer.
摘要翻译： 下式的化合物，其中取代基如本说明书中所定义，其中该化合物可用于治疗癌症。
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4.发明授权Analogues of camptothecin, their use as medicaments and the pharmaceutical compositions containing them 有权喜树碱的类似物，它们作为药物的用途和含有他们的药物组合物公开(公告)号：US07135478B2
公开(公告)日：2006-11-14
申请号：US10930622
申请日：2004-08-31
申请人： Dennis Bigg , Olivier Lavergne , Francesc Pla Rodas , Jacques Pommier , Gérard Ulibarri , Jerry Harnett , Alain Rolland , Anne-Marie Liberatore , Christophe Lanco , Jean-Bernard Cazaux , Christine Le Breton , Eric Manginot
发明人： Dennis Bigg , Olivier Lavergne , Francesc Pla Rodas , Jacques Pommier , Gérard Ulibarri , Jerry Harnett , Alain Rolland , Anne-Marie Liberatore , Christophe Lanco , Jean-Bernard Cazaux , Christine Le Breton , Eric Manginot
IPC分类号： C07D471/00 , A61K31/44
CPC分类号： C07D213/64 , C07D213/61 , C07D471/14 , C07D491/04
摘要： A compound of the formula wherein the substituents are defined as in the specification which compounds are useful in the treatment of cancer.
摘要翻译： 下式的化合物，其中取代基如本说明书中所定义，其中该化合物可用于治疗癌症。
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