METHOD AND SYSTEM FOR PREDICTING ADVERSE DRUG-DRUG INTERACTIONS BY RECOVERING THE MULTI-ATTRIBUTE INFORMATION OF DRUGS, AND MEDIUM

    公开(公告)号:US20240170104A1

    公开(公告)日:2024-05-23

    申请号:US18325572

    申请日:2023-05-30

    IPC分类号: G16C20/30 G16C20/70

    CPC分类号: G16C20/30 G16C20/70

    摘要: The present invention discloses the method and system for predicting adverse drug-drug interactions by recovering the multi-attribute information of drugs and the medium. The method includes: collecting adverse drug-drug interactions data and multi-attribute data of drugs; constructing the recovery model of multi-attribute absent feature of drugs; correcting the recovery model of multi-attribute absent feature of drugs by the cosine similarity regularization term, and solving the corrected recovery model to obtain the common features and unique features of multi-attribute information of drugs; obtaining the multi-attribute information of two drugs, calculating common features and unique features of their multi-attribute information as the inputs of the prediction model to predict their adverse drug-drug interactions. The present invention improves the accuracy of the prediction of the adverse drug-drug interactions, promotes the experimental study of the adverse drug-drug interactions, and ensures the safety of medication.

    Blockchain-based time stamping method for digital signature

    公开(公告)号:US11936799B2

    公开(公告)日:2024-03-19

    申请号:US17032041

    申请日:2020-09-25

    IPC分类号: H04L29/06 H04L9/32 H04L9/00

    摘要: A method for blockchain-based time stamping for digital signature is disclosed. The method includes two participants: a signer who signs a message, a verifier who verifies the message. In the method, the signer obtains hash values of a certain number of latest confirmed blocks in blockchain, binds these hash values and the message together to be a new message. The signer then generates a signature of the new message and inserts identification data of this signature and the new message into a transaction of blockchain. This method ensures that the generation time of the signature is prior to the generation time of the block which contains the signature and, at the same time, is after the generation time of the blocks whose hash values are included in the signature, which produces an accurate time interval for the digital signature.

    RANDOM PHASE MODULATION METHOD DEPENDING ON COMMUNICATION DISTANCE

    公开(公告)号:US20230421284A1

    公开(公告)日:2023-12-28

    申请号:US18033375

    申请日:2021-04-29

    IPC分类号: H04K1/00

    CPC分类号: H04K1/006

    摘要: A random phase modulation method depending on a communication distance is provided. In the method, time synchronization is carried out by means of a transmitter and a receiver, a local random signal is generated, and an original signal to be sent is pre-coded according to a transmission delay and the generated local random signal, such that random phase modulation depending on a communication distance is realized, potential security brought about by positions of the transmitter and the receiver is fully utilized, a receiver at an expected distance position can receive a signal with a correct phase, and a receiver at another distance position receives a signal with a scrambled phase, thereby improving the secure communication capability of a wireless communication system in terms of the dimension of space.