公开(公告)号：US5358694A

公开(公告)日：1994-10-25

申请号：US409654

申请日：1989-09-19

Applicant: Rocco Giovanniello

Inventor： Rocco Giovanniello

IPC: A61K8/28 ,  A61K8/44 ,  A61Q15/00 ,  C01F7/00 ,  C01F7/56 ,  C07C229/76 ,  A61K7/38

CPC classification number: A61Q15/00 ,  A61K8/28 ,  A61K8/44 ,  C01F7/002 ,  C07C229/76 ,  C01P2002/87

Abstract: Polymeric basic aluminum halides having the empirical formula:Al.sub.2 (OH).sub.6-y X.sub.ywhere X is chlorine, bromine or iodine, y has a numerical value from 0.7 to 3, and whose polymer distribution as characterized by size exclusion chromatography is:(a) 100% of the polymers are found in Bands II, III and IV, and(b) Band III contains at least 25% of the polymer; are obtained by reacting aluminum metal with HX in water at a temperature of about 70.degree. C. to about 100.degree. C., where X is halogen, wherein the concentration of product in solution is about 8 to about 35 wt. %.

Abstract translation: 具有以下经验式的聚合碱性卤化铝：其中X为氯，溴或碘的Al 2（OH）6-yXy，y的数值为0.7至3，其尺寸排阻色谱法的聚合物分布如下：（a） 在B带II，III和IV中发现100％的聚合物，（b）带III含有至少25％的聚合物; 在约70℃至约100℃的温度下使铝金属与HX在水中反应，其中X是卤素，其中溶液中的产物浓度为约8至约35重量％。 ％

公开(公告)号：US5603912A

公开(公告)日：1997-02-18

申请号：US404492

申请日：1995-03-17

Applicant: Rocco Giovanniello ,  Anton Treuting

Inventor： Rocco Giovanniello ,  Anton Treuting

IPC: C01F7/00 ,  C02F1/52 ,  C01B17/45

CPC classification number: C01F7/007 ,  C02F1/5245

Abstract: An improved method for preparing a basic aluminum hyrdoxy-chlorosulfate is disclosed comprising reacting a basic aluminum chloride with a sulfate source, i.e. H.sub.2 SO.sub.4 or aluminum sulfate, and modifying the reaction product by the addition of minor amounts of calcium containing compound and a water soluble iron salt. The product is useful in water treatment, is effective in cold water as well as low alkalinity water. A magnesium compound can be added to the composition where the calcium source contains no magnesium.

Abstract translation: 公开了一种制备碱式铝羟基 - 氯代硫酸盐的改进方法，其包括使碱性氯化铝与硫酸盐源（即H 2 SO 4或硫酸铝）反应，并通过加入少量含钙化合物和水溶性铁来改性反应产物 盐。 该产品在水处理中有用，在冷水和低碱度水中有效。 可以在钙源不含镁的组合物中加入镁化合物。

公开(公告)号：US4871525A

公开(公告)日：1989-10-03

申请号：US81638

申请日：1987-08-03

Applicant: Rocco Giovanniello ,  Stephen M. Howe

Inventor： Rocco Giovanniello ,  Stephen M. Howe

IPC: A61K8/28 ,  A61K8/44 ,  A61Q15/00 ,  C01F7/00 ,  C01G25/04 ,  C07C229/76

CPC classification number: A61Q15/00 ,  A61K8/28 ,  A61K8/44 ,  C01F7/002 ,  C07C229/76 ,  A61K2800/58 ,  C01P2002/87

Abstract: Aluminum zirconium hydroxy halide glycinate complex and a method of its preparation is disclosed having an empirical formula:Al.sub.2 (OH).sub.6-y.sup.X.sub.y ZrO(OH).sub.x Cl.sub.2-x /Neutral Amino Acidwherein x has a numerical value of 0 to 1.5, y has a numerical value of 0.7 to 3.0, X is chlorine, bromine or iodine, and whose polymer distribution as characterized by a size exclusion chromatograph is:(a) a peak height ratio of peak 4 to peak 3 of 0.5 to 1.8:1, and(b) peaks (1+2) contain less than 4% of the polymer distribution by weight.

Abstract translation: 公开了铝锆羟基卤甘氨酸络合物及其制备方法，其具有以下经验式：Al 2（OH）6-yXyZrO（OH）xCl 2-x /中性氨基酸，其中x的数值为0至1.5，y具有 数值为0.7〜3.0，X为氯，溴或碘，其特征在于尺寸排阻色谱的聚合物分布为：（a）峰4与峰3的峰高比为0.5〜1.8:1，（ b）峰（1 + 2）含有小于4重量％的聚合物分布。

公开(公告)号：US5955064A

公开(公告)日：1999-09-21

申请号：US955056

申请日：1997-10-21

Applicant: Rocco Giovanniello ,  Nelson Ayala ,  Jing Shen ,  Ketan Shah

Inventor： Rocco Giovanniello ,  Nelson Ayala ,  Jing Shen ,  Ketan Shah

IPC: C01F7/48 ,  A61K7/32 ,  A61K7/34 ,  A61K7/38

CPC classification number: A61Q15/00 ,  A61K8/28 ,  A61K8/44 ,  A61K2800/58

Abstract: An enhanced antiperspirant active having improved stability and a process for preparing the enhanced antiperspirant active solution are disclosed, the process comprises blending an enhanced basic aluminum chlorohydrate antiperspirant active having a peak 4 content of at least 20% (Component A) with a zirconium hydroxychloride neutral amino acid complex (component B) and a conventional basic aluminum chloride (Component C) , the order of addition not being critical; wherein at least 10% by weight of the total aluminum being derived from Component A and about 90% to 10% of the aluminum being derived from Component C; thereby forming a stable antiperspirant active solution of enhanced efficacy, the overall concentration of reactants in solution being about 38% to 55% by weight.

Abstract translation: 公开了具有改进的稳定性的增强的止汗剂活性物和制备增强的止汗剂活性溶液的方法，该方法包括将具有至少20％的峰4含量（组分A）的增强型碱式水合氯化铝止汗剂活性物与羟基氯化中间体 氨基酸复合物（组分B）和常规碱性氯化铝（组分C），加成顺序不是关键的; 其中至少10重量％的总铝衍生自组分A，约90％至10％的铝衍生自组分C; 从而形成稳定的止汗活性溶液，其效果增强，溶液中反应物的总浓度为约38-55重量％。