公开(公告)号：US20230338529A1

公开(公告)日：2023-10-26

申请号：US18019627

申请日：2021-08-05

申请人： The Children's Medical Center Corporation

发明人： Zhigang HE ,  Yi LI ,  Xuelian HE

IPC分类号： A61K31/336 ,  A61K39/00 ,  A61P17/02 ,  A61K38/55 ,  A61K31/404 ,  A61P25/00

CPC分类号： A61K39/4614 ,  A61K31/336 ,  A61K31/404 ,  A61K38/55 ,  A61K39/4633 ,  A61K39/4637 ,  A61K39/464 ,  A61K39/4644 ,  A61K39/464402 ,  A61K39/464429 ,  A61P17/02 ,  A61P25/00

摘要： Provided herein are compositions and methods for reducing neuroinflammation and treating neurodegenerative diseases using proteinase inhibitors. The invention also provides methods for reducing post-injury scar formation in the central nervous system.