公开(公告)号：US10858338B2

公开(公告)日：2020-12-08

申请号：US16084465

申请日：2017-03-14

申请人： The Regents of the University of California

发明人： Bruce Hammock ,  Sean Kodani

IPC分类号： C07D401/06 ,  C07D271/10 ,  C07D211/16 ,  C07D211/46 ,  C07D401/12 ,  C07D401/14 ,  C07D413/14 ,  C07D417/04 ,  C07C275/28 ,  C07C275/34 ,  A61P35/00 ,  C07C275/36

摘要： The present invention provides compounds that are dual inhibitors of soluble epoxide hydrolase and fatty acid amide hydrolase. The present invention also provides methods of using the compounds to inhibit soluble epoxide hydrolase and fatty acid amide hydrolase, and to treat cancer.

公开(公告)号：US20190077785A1

公开(公告)日：2019-03-14

申请号：US16084465

申请日：2017-03-14

申请人： The Regents of the University of California

发明人： Bruce HAMMOCK ,  Sean KODANI

IPC分类号： C07D401/06 ,  C07D401/14 ,  C07D401/12 ,  C07D417/04 ,  C07D413/14 ,  C07D211/16 ,  C07D211/46 ,  C07C275/36 ,  A61P35/00

摘要： The present invention provides compounds that are dual inhibitors of soluble epoxide hydrolase and fatty acid amide hydrolase. The present invention also provides methods of using the compounds to inhibit soluble epoxide hydrolase and fatty acid amide hydrolase, and to treat cancer.

公开(公告)号：US11873288B2

公开(公告)日：2024-01-16

申请号：US17112713

申请日：2020-12-04

申请人： The Regents of the University of California

发明人： Bruce Hammock ,  Sean Kodani

IPC分类号： C07D401/06 ,  C07C275/28 ,  C07D271/10 ,  C07C275/34 ,  A61P35/00 ,  C07C275/36 ,  C07D211/16 ,  C07D211/46 ,  C07D401/12 ,  C07D401/14 ,  C07D413/14 ,  C07D417/04

CPC分类号： C07D401/06 ,  A61P35/00 ,  C07C275/28 ,  C07C275/34 ,  C07C275/36 ,  C07D211/16 ,  C07D211/46 ,  C07D271/10 ,  C07D401/12 ,  C07D401/14 ,  C07D413/14 ,  C07D417/04 ,  C07C2601/14

摘要： The present invention provides compounds that are dual inhibitors of soluble epoxide hydrolase and fatty acid amide hydrolase. The present invention also provides methods of using the compounds to inhibit soluble epoxide hydrolase and fatty acid amide hydrolase, and to treat cancer.