公开(公告)号：US06648832B2

公开(公告)日：2003-11-18

申请号：US09777629

申请日：2001-02-06

申请人： Joseph A. Orr ,  Scott A. Kofoed ,  Dwayne Westenskow ,  Michael B. Jaffe

发明人： Joseph A. Orr ,  Scott A. Kofoed ,  Dwayne Westenskow ,  Michael B. Jaffe

IPC分类号： A61B6500

CPC分类号： A61B5/029 ,  A61B5/0836 ,  A61M16/0045 ,  A61M16/0833 ,  A61M2016/0036 ,  A61M2230/432 ,  G01N33/004 ,  Y02A50/243

摘要： Apparatus and methods for non-invasively determining the cardiac output or pulmonary capillary blood flow of a patient using partial re-breathing techniques. The apparatus includes a substantially instantaneously adjustable deadspace volume for accommodating differences in sizes or breathing capacities of various patients. The apparatus may be constructed of inexpensive elements, including one or more two-way valves, which render the apparatus very simple to use and inexpensive so that the unit may be employed as a disposable product. The method of the invention includes estimating the cardiac output or pulmonary capillary blood flow of a patient based on partial pressure of alveolar CO2, rather than on the partial pressure of end tidal CO2, as previously practiced. A computer program for calculating the cardiac output or pulmonary capillary blood flow of a patient is also disclosed.

摘要翻译： 使用部分再呼吸技术非侵入性地确定患者的心输出量或肺毛细血管血流量的装置和方法。 该装置包括基本上即时可调的死空间体积，用于适应各种患者的尺寸或呼吸能力的差异。 该设备可以由廉价的元件构成，包括一个或多个双向阀，这使得该设备使用起来非常简单并且便宜，使得该单元可以用作一次性产品。 本发明的方法包括基于肺泡二氧化碳的分压来估计患者的心输出量或肺毛细血管血流量，而不是如先前所述的结束潮汐CO 2的分压。 还公开了一种用于计算患者的心输出量或肺毛细血管血流量的计算机程序。

公开(公告)号：US06272363B1

公开(公告)日：2001-08-07

申请号：US09003413

申请日：1998-01-06

申请人： James R. Casciani ,  Paul D. Mannheimer ,  Steve L. Nierlich ,  Stephen J. Ruskewicz

发明人： James R. Casciani ,  Paul D. Mannheimer ,  Steve L. Nierlich ,  Stephen J. Ruskewicz

IPC分类号： A61B6500

CPC分类号： A61B5/1464 ,  A61B5/14542 ,  A61B5/7207 ,  A61B2562/0242 ,  H01L2224/32245 ,  H01L2224/48091 ,  H01L2224/48247 ,  H01L2224/73265 ,  H01L2924/3011 ,  H01L2924/00014 ,  H01L2924/00

摘要： A pulse oximeter sensor with a light source optimized for low oxygen saturation ranges and for maximizing the immunity to perturbation induced artifact. Preferably, a red and an infrared light source are used, with the red light source having a mean wavelength between 700-790 nm. The infrared light source can have a mean wavelength as in prior art devices used on patients with high saturation. The sensor of the present invention is further optimized by arranging the spacing between the light emitter and light detectors to minimize the sensitivity to perturbation induced artifact. The present invention optimizes the chosen wavelengths to achieve a closer matching of the absorption and scattering coefficient products for the red and IR light sources. This optimization gives robust readings in the presence of perturbation artifacts including force variations, tissue variations and variations in the oxygen saturation itself.

摘要翻译： 具有针对低氧饱和度范围优化的光源的脉搏血氧饱和度传感器，并最大限度地提高对扰动诱发的伪影的免疫力。 优选地，使用红色和红外光源，红色光源的平均波长在700-790nm之间。 红外光源可以具有与用于高饱和度患者的现有技术装置中的平均波长。 通过布置光发射器和光检测器之间的间距来进一步优化本发明的传感器，以最小化对扰动诱发的伪影的灵敏度。 本发明优化所选择的波长，以实现红色和红外光源的吸收和散射系数乘积的更接近的匹配。 这种优化在存在扰动伪影的情况下提供鲁棒的读数，包括力变化，组织变化和氧饱和度本身的变化。