公开(公告)号：US06600071B2

公开(公告)日：2003-07-29

申请号：US10228373

申请日：2002-08-27

申请人： Norbert Götz ,  Roland Götz ,  Michael Rack

发明人： Norbert Götz ,  Roland Götz ,  Michael Rack

IPC分类号： C07C24330

CPC分类号： C07C243/30 ,  C07D231/20

摘要： A process for preparing compounds of the formula I in which R1 is hydrogen, an aliphatic group having 1-8 carbon atoms, Cl-C6-alkoxycarbonyl, Cl-C6-alkylthiocarbonyl or a cyclic ring system having 3-14 ring atoms, and R2 is hydrogen, an aliphatic group having 1-8 carbon atoms, or R1 and R2 together with the carbon atom to which they are bound form a cyclic or bicyclic ring system having 3-14 ring atoms, comprises the preparation of compounds of the formula II in which R3 and R4 are readily detachable groups and R1 and R2 are as defined above, as starting materials or intermediates and the cyclization of these under suitable reaction conditions to give compounds of the formula I. The intermediates of the formula II are novel.

摘要翻译： 制备式Iin的化合物的方法，其中R1是氢，具有1-8个碳原子的脂族基团，C1-C6-烷氧基羰基，C1-C6-烷硫基羰基或具有3-14个环原子的环状体系，R2是 氢，具有1-8个碳原子的脂族基团，或者R1和R2与它们所连接的碳原子一起形成具有3-14个环原子的环状或双环体系，包括制备式II化合物，其中式 R3和R4是容易拆分的基团，R1和R2如上所定义，作为原料或中间体，并在合适的反应条件下环化，得到式I化合物。式II的中间体是新的。