公开(公告)号：US06242607B1

公开(公告)日：2001-06-05

申请号：US09437362

申请日：1999-11-10

申请人： Philippe Camus ,  Marcel Descamps ,  Joël Radisson

发明人： Philippe Camus ,  Marcel Descamps ,  Joël Radisson

IPC分类号： C07D2404

CPC分类号： C07D401/04 ,  C07D211/88 ,  C07D409/04

摘要： The invention relates to glutarimides of formula (I): in which Ar represents a phenyl non substituted or substituted one or more times with one of the substituents selected from a halogen atom, a hydroxyl, a (C1-C4)alkoxy, a trifluoromethyl, a (C1-C4)alkyl, said substituents being identical or different; a pyridyl group; a thienyl group and X is methylene or ethylene, their salts and their enantiomers, as well as their method of preparation and their use for the preparation of the corresponding 3,3-disubstituted piperidines.

摘要翻译： 本发明涉及式（I）的戊二酰亚胺：其中Ar表示未取代或取代一个或多个选自卤原子，羟基，（C 1 -C 4）烷氧基，三氟甲基， （C 1 -C 4）烷基，所述取代基相同或不同; 吡啶基; 噻吩基，X是亚甲基或亚乙基，它们的盐及其对映异构体，以及它们的制备方法及其用于制备相应的3,3-二取代的哌啶的用途。