专利检索 ipc:"C12N1931" 第 1 页

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发明授权
Method and probes for the identification of microbial genes specifically induced during host infection 失效
标题翻译：用于鉴定在宿主感染期间特异性诱导的微生物基因的方法和探针

公开(公告)号：US06365401B1

公开(公告)日：2002-04-02

申请号：US08651155

申请日：1996-05-17

申请人： Michael J. Mahan , Christopher P. Conner , Douglas M. Heithoff

发明人： Michael J. Mahan , Christopher P. Conner , Douglas M. Heithoff

IPC分类号： C12N1931

CPC分类号： C07K14/255 , A61K39/00 , C07K2319/00 , C12Q1/02 , C12Q1/04 , C12Q1/689 , C12Q1/6897 , C12Q2600/158

摘要： The present invention relates to a class of microbial coding sequences the transcription or cotranscription of which is specifically induced during microbial infection of a host. These particular coding sequences or defined regions thereof may be used as probes to identify and isolate microbial virulence genes. The products of these virulence genes will provide potential targets for the development of vaccines or antimicrobial agents.

摘要翻译： 本发明涉及一种微生物编码序列，其转录或转录在宿主的微生物感染过程中被特异性诱导。这些特定的编码序列或其限定的区域可用作鉴定和分离微生物毒力基因的探针。这些毒力基因的产物将为疫苗或抗微生物剂的开发提供潜在的目标。