公开(公告)号：US20230372406A1

公开(公告)日：2023-11-23

申请号：US18214062

申请日：2023-06-26

申请人： IMMUNE MACRO-BIOTIC TECHNOLOGY UK LIMITED

发明人： Christopher Jeremy Leonard

IPC分类号： A61K35/64 ,  A61K35/63

CPC分类号： A61K35/64 ,  A61K35/63

摘要： An improved method for the manufacture of a medicament, which method includes the use of tissues, larval forms or derivatives of insects that have been fed on food containing pathogens.

公开(公告)号：US20200276122A1

公开(公告)日：2020-09-03

申请号：US16811515

申请日：2020-03-06

申请人： The Regents of the University of California

发明人： Liangfang Zhang ,  Che-Ming Jack Hu ,  Weiwei Gao ,  Jonathan Copp

IPC分类号： A61K9/06 ,  A61K9/16 ,  A61K9/51 ,  A61K38/17 ,  A61K35/17 ,  A61K35/18 ,  A61K35/19 ,  A61K35/58 ,  A61K35/63 ,  A61K45/06 ,  A61K31/49 ,  A61L26/00 ,  A61K9/00 ,  A61L27/52 ,  A61L27/54

摘要： The present invention provides for compositions comprising a polymeric hydrogel impregnated with a toxin-absorbing or binding nanoparticle. The present invention also provides for the use of the above compositions for decreasing or neutralizing the effect of a toxin, or for treating or preventing an infection by a microbe that produces a toxin, in a subject. The exemplary toxin is a biological toxin such as a viral, bacterial, fungal, plant or animal toxin.

公开(公告)号：US10420804B2

公开(公告)日：2019-09-24

申请号：US15465414

申请日：2017-03-21

申请人： Manuka Health New Zealand Limited

发明人： Kerry Paul ,  Owen John Catchpole ,  Darina Lazarova

IPC分类号： A61K35/644 ,  A61K47/69 ,  A61K9/16 ,  A61K47/40 ,  A61K35/63 ,  A61K9/19 ,  A61K45/06 ,  A61K31/192 ,  A61K31/216 ,  A61K31/352 ,  A61K31/353 ,  A61K9/51

摘要： This invention provides pharmaceutical compositions, including anti-gastrointestinal cancer compositions, containing propolis and cyclodextrin. Methods of using such compositions, in particular in the treatment or prevention of gastrointestinal cancers, and the resensitization of gastrointestinal cancers to therapy are also provided.

公开(公告)号：US20190142746A1

公开(公告)日：2019-05-16

申请号：US16139612

申请日：2018-09-24

申请人： The Regents of the University of California

发明人： Liangfang Zhang ,  Che-Ming Jack Hu ,  Weiwei Gao ,  Jonathan Coop

IPC分类号： A61K9/06 ,  A61L27/54 ,  A61L27/52 ,  A61K9/16 ,  A61K38/17 ,  A61K35/17 ,  A61K9/00 ,  A61K9/51 ,  A61L26/00 ,  A61K31/49 ,  A61K45/06 ,  A61K35/63 ,  A61K35/58 ,  A61K35/19 ,  A61K35/18

摘要： The present invention provides for compositions comprising a polymeric hydrogel impregnated with a toxin-absorbing or binding nanoparticle. The present invention also provides for the use of the above compositions for decreasing or neutralizing the effect of a toxin, or for treating or preventing an infection by a microbe that produces a toxin, in a subject. The exemplary toxin is a biological toxin such as a viral, bacterial, fungal, plant or animal toxin.

公开(公告)号：US20190070239A1

公开(公告)日：2019-03-07

申请号：US16082939

申请日：2017-03-03

申请人： Yin Bong CHENG ,  Cheng Lab & Company, LLC

发明人： Yin Bong Cheng

IPC分类号： A61K36/40 ,  A61K36/481 ,  A61K36/076 ,  A61K36/536 ,  A61K36/756 ,  A61K35/63

摘要： An edible herbal formulation which raises the alkalinity of the human body in a short period of time is disclosed. The major ingredient in the formulation is Camptotheca. Additional ingredients that may be included are poria cocos, astragalus membranacaus, ostrea vivularis gould, prunella vulgaris, bombyx mori and phellodendron amurense Rupr. While the herbal formulation may be a mixture containing Camptotheca and all or some of the above ingredients, it is most preferred that the herbal formulation include the three ingredients of Camptotheca, poria cocos and astragalus membranacaus.

公开(公告)号：US09969787B2

公开(公告)日：2018-05-15

申请号：US15238126

申请日：2016-08-16

申请人： Zealand Pharma A/S

发明人： Rasmus Just ,  Kirsten Lindegaard Bovbjerg ,  Ditte Riber ,  Wayne Shaun Russell

IPC分类号： A61K38/00 ,  C07K14/00 ,  C07K14/605 ,  A61K38/26 ,  A61K35/22 ,  A61K35/48 ,  A61K35/54 ,  A61K35/64 ,  A61K45/06 ,  A61K35/63

CPC分类号： C07K14/605 ,  A61K35/22 ,  A61K35/48 ,  A61K35/54 ,  A61K35/63 ,  A61K35/64 ,  A61K38/26 ,  A61K45/06

摘要： GLP-2 analogs are disclosed which comprise one of more substitutions as compared to h[Gly2]GLP-2 and which may have the property of an altered GLP-1 activity, and their medical use. The analogs are particularly useful for the prophylaxis treatment or ameliorating of the gastro-intestinal associated side effects of diabetes.

公开(公告)号：US09827273B2

公开(公告)日：2017-11-28

申请号：US14395478

申请日：2012-08-21

申请人： Villorij Ivanovich Strukov ,  Olga Jhones ,  Evgenij Nikolaevich Krutiakov ,  Konstantin Gennad'evich Elistratov

发明人： Villorij Ivanovich Strukov ,  Olga Jhones ,  Evgenij Nikolaevich Krutiakov ,  Konstantin Gennad'evich Elistratov

IPC分类号： A61K35/64 ,  A61K31/592 ,  A61K31/593 ,  A61K45/06 ,  A61K35/63

CPC分类号： A61K35/64 ,  A61K31/592 ,  A61K31/593 ,  A61K35/63 ,  A61K45/06 ,  A61K2300/00

摘要： The invention related to medicine, in particular, to a method and a preparation for preventing and treating atypical osteoporosis with normal or increased bone tissue mineralization with the presence of cavities in trabecular bone sections (and conditions similar thereto involving excess mass and metabolic syndrome). The method comprises administrating a preparation comprising from 10 mg and 1000 mg of drone brood per day and from 50 IU and 100,000 IU of vitamin D or vitamins of the group D and/or active metabolites thereof per day. The preparation comprising drone brood and vitamin D or vitamins of the group D and/or active metabolites thereof can be in a powder, tablet or capsule form. The method and the preparation provide redistributing calcium in the body, reducing mineralization of soft tissues, vessels and other organs, and filling cavities in trabecular bone.

公开(公告)号：US20050124703A1

公开(公告)日：2005-06-09

申请号：US10991340

申请日：2004-11-16

申请人： Qi Jia ,  Ji-Fu Zhao

发明人： Qi Jia ,  Ji-Fu Zhao

IPC分类号： A61K31/045 ,  A61K35/63 ,  A61K35/64 ,  A01N31/00

CPC分类号： A61K31/045 ,  A61K35/63 ,  Y10S514/925 ,  A61K2300/00

摘要： The present invention provides a novel method for the preparation of a unique profile of primary aliphatic alcohols, having 24 to 30 carbon atoms, from the wax secreted by the insect Ericerus pela. Included in the present invention is the composition of matter, referred to herein as “polycosanol” produced by the method of this invention. The polycosanol composition is comprised primarily of the four primary aliphatic alcohols, tetracosanol, hexacosanol, octacosanol and triacontanol. Further included in this invention is the use of said composition of matter for the prevention and treatment of obesity, syndrome X, diabetes, hypercholesterolemia, atherosclerotic complications, ischemia and thrombosis.

公开(公告)号：US5958887A

公开(公告)日：1999-09-28

申请号：US102335

申请日：1998-06-22

申请人： Michael Hansen ,  Ole Gyring Nieben

发明人： Michael Hansen ,  Ole Gyring Nieben

IPC分类号： A61K38/00 ,  A61K35/63 ,  A61P31/12 ,  A61P31/22 ,  A61K39/245

CPC分类号： A61K35/64 ,  A61K38/1767 ,  Y10S514/886 ,  Y10S514/887 ,  Y10S514/931 ,  Y10S514/934 ,  Y10S530/858

摘要： The present invention relates to the use of hymenoptera venom or proteinaceous or polypeptide components contained therein in the manufacture of a medicament for treating DNA virus infections, and to a method for treatment of mammalian DNA virus infections which uses hymenoptera venom or proteinaceous or polypeptide components contained therein.

摘要翻译： 本发明涉及用于制备用于处理DNA病毒感染的药物中的men虫毒液或蛋白质或多肽组分的用途，以及用于治疗哺乳动物DNA病毒感染的方法，所述哺乳动物DNA病毒感染使用含有昆虫毒素或蛋白质或多肽的成分 其中。

公开(公告)号：US11154578B2

公开(公告)日：2021-10-26

申请号：US15327970

申请日：2015-07-20

申请人： Melcare Medical Pty Ltd

发明人： Anthony Peter Moloney

IPC分类号： A61K35/644 ,  A61K9/00 ,  A61K47/12 ,  A61K9/08 ,  A61K36/61 ,  A61K35/63 ,  A61K47/02 ,  A61L15/40

摘要： The present invention provides a composition comprising honey, a preservative and an aqueous carrier, wherein the honey is present in an amount in the range of from 2 to 50% w/w. Uses of the compositions of the invention for the management, treatment or prevention of a respiratory, ophthalmic, ear or vaginal condition in a subject, and for wound management are also described.