公开(公告)号：WO1996034561A1

公开(公告)日：1996-11-07

申请号：PCT/US1996006030

申请日：1996-05-01

Applicant: HEART RHYTHM TECHNOLOGIES, INC.

Inventor： HEART RHYTHM TECHNOLOGIES, INC. ,  CASTELLANO, Thomas, M. ,  HAYZELDEN, Robert, C. ,  MAAHS, Tracy, D.

IPC: A61B08/00

CPC classification number: A61B17/2202 ,  A61B2017/00084 ,  A61B2017/00092 ,  A61B2017/00243

Abstract: A catheter (18) includes a piezoelectric transducer (24) mounted to the distal end (20). The band electrode (26), proximal to the piezoelectric transducer (24), may be used either individually or simultaneously with the tip electrode (22). In one embodiment, the piezoelectric transducer has the shape of a cylinder and, in another embodiment, a convex shape with a mounting flange. In the cylindrical shape, a plurality of surface mounted temperature sensors (28) are disposed within the piezoelectric transducer (24). The sensors (28) are electrically insulated and a sealing technique prevents the leakage of body fluids from penetrating the interior of the catheter through the sensor bores. The cylindrical transducer is supported on mounting members so that it is accurately mounted and sealed while, at the same time, the material used does not significantly dampen the transducer (24).

Abstract translation: 导管（18）包括安装到远端（20）的压电换能器（24）。 靠近压电换能器（24）的带状电极（26）可以单独使用或与尖端电极（22）同时使用。 在一个实施例中，压电换能器具有圆柱体的形状，在另一实施例中，具有安装凸缘的凸形形状。 在圆筒形状中，多个表面安装温度传感器（28）设置在压电换能器（24）内。 传感器（28）是电绝缘的，并且密封技术防止体液泄漏通过传感器孔穿透导管内部。 圆柱形换能器被支撑在安装构件上，使得其被精确地安装和密封，同时所使用的材料不会显着地损坏换能器（24）。

公开(公告)号：WO1998011826A1

公开(公告)日：1998-03-26

申请号：PCT/US1997015870

申请日：1997-09-09

Applicant: HEART RHYTHM TECHNOLOGIES, INC.

Inventor： HEART RHYTHM TECHNOLOGIES, INC. ,  SHERMAN, Marshall, L. ,  CASTELLANO, Thomas, M.

IPC: A61B17/00

CPC classification number: A61B17/2202 ,  A61B2017/00084 ,  A61B2017/00092 ,  A61B2017/00243

Abstract: An energy delivery system and method control the frequency of the power driving an ultrasonic device (24) to achieve more efficient power delivery. During operation of the ultrasonic device to deliver power to a patient site (16), the system and method automatically sweep the drive power through a frequency range, locate the series and parallel resonance frequencies, calculate the average of those frequencies and lock the power generator at that average frequency to drive the crystal. This frequency sweep procedure occurs automatically when the ultrasonic crystal is located at the patient site and the power generator operator presses the power-on switch to apply power. The method of tuning the power generator thus occurs when the crystal is at the site temperature and is transparent to the operator. The application of an external bio-layer to the crystal increases its bandwidth and its robustness. Mounting a temperature sensor (28) or sensors at the crystal permits monitoring of the crystal temperature and allows drive level control over the power generator to control the temperature at the crystal.

Abstract translation: 能量输送系统和方法控制驱动超声波装置（24）的功率的频率以实现更有效的功率输送。 在超声波设备运行期间向病人站点输送功率（16）时，系统和方法通过频率范围自动扫描驱动功率，定位串联和并联谐振频率，计算出这些频率的平均值并锁定发电机 以平均频率驱动晶体。 当超声波晶体位于患者现场时，该频率扫描过程自动发生，发电机操作者按下电源开关以施加电力。 因此，当晶体处于现场温度并且对操作者是透明的时，调谐发电机的方法发生。 外部生物层在晶体上的应用增加了其带宽和其鲁棒性。 在晶体上安装温度传感器（28）或传感器可以监控晶体温度，并允许发电机的驱动电平控制来控制晶体的温度。

公开(公告)号：WO1997017893A1

公开(公告)日：1997-05-22

申请号：PCT/US1996017676

申请日：1996-11-12

Applicant: HEART RHYTHM TECHNOLOGIES, INC.

Inventor： HEART RHYTHM TECHNOLOGIES, INC. ,  PAISNER, William, Lee

IPC: A61B05/042

CPC classification number: A61B5/6852 ,  A61B5/0422

Abstract: An electrogram analysis system and method for determining the quality of information gathered from electrical signals in biological tissue. The system comprises a catheter (14) having an array (16) of at least two electrodes (18) at its distal end, the electrodes (18) detecting electrical signals to a processor (28). The processor (28) processes the relayed signals into waveforms and computes a quality of the relayed signals. The quality of the relayed signals is used to select higher quality signals for further analysis, such as site of origin determination and mapping. The relayed signals from the electrodes (18) may also be used to determine a quality for a particular electrode channel. When the invention is used in cardiac applications, the relayed signal quality may comprise two components - a channel quality and a beat quality. The channel quality represents the value of information received from a particular electrode and channel, while the beat quality represents the value of a particular heart beat across all channels. The signal quality is displayed to the user. In cardiac applications, the channel quality can be displayed (34) in a format corresponding to the shape of the electrode array, with channel quality from each electrode positioned in a corresponding position on the display (30). The display (30) may also show the waveforms of the signal, such as the heart beat waveform (32) in a cardiac procedure.

Abstract translation: 一种用于确定从生物组织中的电信号收集的信息的质量的电描记图分析系统和方法。 该系统包括在其远端具有至少两个电极（18）的阵列（16）的导管（14），电极（18）检测到处理器（28）的电信号。 处理器（28）将中继的信号处理成波形并计算中继信号的质量。 中继信号的质量用于选择较高质量的信号进行进一步分析，如原点确定和映射。 来自电极（18）的中继信号也可用于确定特定电极通道的质量。 当本发明用于心脏应用时，中继信号质量可以包括两个组件 - 信道质量和节拍质量。 信道质量表示从特定电极和信道接收的信息的值，而节拍质量表示所有信道上的特定心跳的值。 信号质量显示给用户。 在心脏应用中，可以以对应于电极阵列的形状的格式显示（34）通道质量，其中来自每个电极的通道质量位于显示器（30）上的对应位置。 显示器（30）还可以显示心脏过程中的诸如心跳波形（32）的信号的波形。

公开(公告)号：WO1996034652A1

公开(公告)日：1996-11-07

申请号：PCT/US1996006057

申请日：1996-05-01

Applicant: HEART RHYTHM TECHNOLOGIES, INC.

Inventor： HEART RHYTHM TECHNOLOGIES, INC. ,  RUSK, Scott, J. ,  JUNG, Eugene, J., Jr. ,  BOWE, Wade, A. ,  SIMPSON, John, A.

IPC: A61M37/00

CPC classification number: A61M25/0147 ,  A61B18/1492 ,  A61B2018/00214 ,  A61B2018/00916 ,  A61M25/0136 ,  A61M2025/015

Abstract: This invention is a steerable catheter (10) comprising a resilient deflectable body member (14) having an expandable electrode array (18) at the distal end thereof, and a manipulation handle (12) attached to the proximal end of the body member, the handle including an array deployment device (26). A mandrel (26) is movable through the shaft of the catheter by control movements at the handle to deploy the array or collapse the array as selected. A displacement compensation system (157) is operatively connected to the mandrel such that when the array is expanded, the compensation system biases the mandrel so to keep the array expanded, even during instances of deflection of the distal end. Similarly, the displacement compensation system biases the mandrel to keep the array collapsed when that configuration is selected, even during instances of straightening of the catheter. The displacement compensation system also compensates for overturning the control device in the handle to protect the array and deployment systems.

Abstract translation: 本发明是一种可导向的导管（10），其包括在其远端处具有可扩张电极阵列（18）的弹性可偏转主体构件（14）和附接到主体构件的近端的操纵手柄（12） 手柄，包括阵列展开装置（26）。 心轴（26）可以通过手柄处的控制运动而移动穿过导管的轴，以部署阵列或使所选阵列折叠。 位移补偿系统（157）可操作地连接到心轴，使得当阵列膨胀时，补偿系统偏压心轴，以便即使在远端的偏转的实例期间也使阵列保持阵列扩张。 类似地，即使在导尿管矫正的情况下，位移补偿系统也会偏心心轴以保持阵列在选择该构型时收缩。 位移补偿系统还补偿了手柄中的控制装置的翻转，以保护阵列和展开系统。

公开(公告)号：WO1996034650A1

公开(公告)日：1996-11-07

申请号：PCT/US1996006033

申请日：1996-05-01

Applicant: HEART RHYTHM TECHNOLOGIES, INC.

Inventor： HEART RHYTHM TECHNOLOGIES, INC. ,  SMITH, Iain

IPC: A61M37/00

CPC classification number: A61M25/0144 ,  A61B2018/00916 ,  A61M25/0136 ,  A61M25/0147 ,  A61M2025/015

Abstract: This invention is a locking mechanism (28) for a steerable catheter (10), the catheter (10) comprising a resilient body member (12) having a restoring force that tends to maintain the body member (12) at a predetermined orientation, a manipulation handle (11) including a control element (24), and a second element (34) movable in relation to one another and adapted for controlling the orientation of the body member (12). The locking mechanism (28) maintains the selected deflection of the body member against the restoring force but permits the physician to overcome the locking force by moving the control element (24). The locking device (28) has a biasing member (168) and a contact member (156) mounted between the control element (24) and the second element (34). The biasing member (168) urges the contact member (156) into frictional contact with one of the elements for holding the control element at the selected longitudinal position.

Abstract translation: 本发明是一种用于可转向导管（10）的锁定机构（28），该导管（10）包括弹性本体构件（12），该弹性体构件具有倾向于将本体构件（12）保持在预定取向的恢复力， 包括控制元件（24）的操纵手柄（11）和可相对于彼此移动并适于控制主体构件（12）的取向的第二元件（34）。 锁定机构（28）抵抗恢复力保持身体构件的选定偏转，但允许医师通过移动控制元件（24）来克服锁定力。 锁定装置（28）具有偏置构件（168）和安装在控制元件（24）和第二元件（34）之间的接触构件（156）。 偏置构件（168）促使接触构件（156）与用于将控制元件保持在所选择的纵向位置的元件之一摩擦接触。

公开(公告)号：WO1996034653A1

公开(公告)日：1996-11-07

申请号：PCT/US1996006061

申请日：1996-05-01

Applicant: HEART RHYTHM TECHNOLOGIES, INC.

Inventor： HEART RHYTHM TECHNOLOGIES, INC. ,  THORNTON, Peter ,  MAAHS, Tracy, D. ,  HAYZELDEN, Robert, C. ,  TAIMISTO, Miriam, H.

IPC: A61M37/00

CPC classification number: A61M25/0144 ,  A61M25/0136 ,  A61M25/0147 ,  A61M2025/015

Abstract: A steerable catheter (10) comprising a resilient body member (12), a manipulation handle (11) attached to the proximal end of the body member (12), a control wire (20) extending from the handle (11) to the distal end (16) of the catheter for deflection control, and a pulley mechanism (26) for controlling the movement of the control wire (20). Longitudinal movement of a slide element (24) in the handle (11) causes movement of the control wire (20) and control over the deflection of the distal end of the catheter. The pulley mechanism (26) is connected between the slide element (24) and the control wire (20) to provide greater mechanical advantage to effect deflection of the body member (12) while enhancing deflection control resolution. A stiffening member (30) is also disposed in the catheter body member (12) and its position is controlled by the rotational motion of the slide element (24). The position of the pulley mechanism (26) is not affected by rotational motion of the slide element (24).

Abstract translation: 包括弹性体构件（12），附接到主体构件（12）的近端的操纵手柄（11）的可导向导管（10），从手柄（11）延伸到远端 用于偏转控制的导管的端部（16）和用于控制控制线（20）的移动的滑轮机构（26）。 滑动元件（24）在手柄（11）中的纵向移动导致控制线（20）的移动并控制导管远端的偏转。 滑轮机构（26）连接在滑动元件（24）和控制线（20）之间，以提供更大的机械优点来实现主体部件（12）的偏转，同时增强偏转控制分辨率。 加强构件（30）也设置在导管本体构件（12）中，并且其位置由滑动元件（24）的旋转运动控制。 滑轮机构（26）的位置不受滑动元件（24）的旋转运动的影响。

公开(公告)号：WO1996034567A1

公开(公告)日：1996-11-07

申请号：PCT/US1996006048

申请日：1996-05-01

Applicant: HEART RHYTHM TECHNOLOGIES, INC.

Inventor： HEART RHYTHM TECHNOLOGIES, INC. ,  SHERMAN, Marshall, L.

IPC: A61B17/36

CPC classification number: A61B17/22012 ,  A61B18/1206 ,  A61B18/1492 ,  A61B2017/00026 ,  A61B2017/00092 ,  A61B2017/00123 ,  A61B2017/00185 ,  A61B2018/00351 ,  A61B2018/00702 ,  A61B2018/00726 ,  A61B2018/0075 ,  A61B2018/00761 ,  A61B2018/00791 ,  A61B2018/00869 ,  A61B2018/00886 ,  A61B2018/046

Abstract: This invention is a power control system and method that controls a power generator (50) to vary the duty cycle of a power output provided to a delivery instrument (10) for delivering that power to a site in a patient for ablation. The peak power can be raised and the duty cycle lowered to result in deeper lesions. A power output having a higher peak power for producing deeper lesions can be obtained by using a lower duty cycle having a longer "off" period in order to deliver more power to the ablation site without overheating the delivery instrument (10). The temperature of the delivery instrument is monitored, and the duty cycle is lowered when the temperature exceeds a predetermined maximum limit. After the instrument has cooled sufficiently, the duty cycle is then increased to its previous level.

Abstract translation: 本发明是一种功率控制系统和方法，其控制功率发生器（50）改变提供给输送器具（10）的功率输出的占空比，用于将该功率传送到患者用于消融的部位。 可以提高峰值功率，降低占空比导致更深的病变。 具有较高峰值功率以产生更深的损伤的功率输出可以通过使用具有较长的“关闭”周期的较低占空比来获得，以便在不会使输送器具（10）过热的情况下向消融部位输送更多功率。 监测输送仪器的温度，当温度超过预定的最大极限时，占空比降低。 仪器充分冷却后，占空比增加到先前水平。

公开(公告)号：WO1996034560A1

公开(公告)日：1996-11-07

申请号：PCT/US1996006032

申请日：1996-05-01

Applicant: HEART RHYTHM TECHNOLOGIES, INC.

Inventor： HEART RHYTHM TECHNOLOGIES, INC. ,  JUNG, Eugene, J., Jr. ,  RUSK, Scott, J.

IPC: A61B05/042

CPC classification number: A61M25/0136 ,  A61B5/0422 ,  A61B18/1492 ,  A61B2018/00214 ,  A61M25/0147 ,  A61M25/04 ,  A61M2025/015 ,  A61M2025/0188 ,  A61N1/056

Abstract: This invention is an expandable electrode array (18) mountable to the distal end of a catheter (10). The expandable array includes a plurality of adjacent elongated segments (20) preformed with proximal, medial and distal hinge portions wherein at least one electrode (22) is mounted on at least one of the segments (20). Each of the plurality of peripheral segments (20) is integrally formed with a resilient conductive longitudinal core encapsulated in an electrically insulated material. A deployment mandrel (26) is operatively connected to each of the respective peripheral segments (20) whereby movement of the mandrel (26) in the proximal direction causes the respective peripheral segments (20) to bend outwardly about the proximal, medial and distal hinge portions to radially expand the segments (20) relative to one another so that the electrodes (22) moves to a predetermined transverse coplanar orientation.

Abstract translation: 本发明是可安装到导管（10）的远端的可扩张电极阵列（18）。 可扩展阵列包括预先形成有近端，内侧和远端铰链部分的多个相邻的细长段（20），其中至少一个电极（22）安装在至少一个段（20）上。 所述多个周边部分（20）中的每一个与封装在电绝缘材料中的弹性导电纵向芯体整体形成。 部署心轴（26）可操作地连接到每个相应的外围段（20），由此心轴（26）沿近侧方向的移动导致相应的周边段（20）围绕近端，内侧和远端铰链向外弯曲 用于相对于彼此径向扩张所述段（20）的部分，使得所述电极（22）移动到预定的横向共面取向。

公开(公告)号：WO1996034558A1

公开(公告)日：1996-11-07

申请号：PCT/US1996006031

申请日：1996-05-01

Applicant: HEART RHYTHM TECHNOLOGIES, INC.

Inventor： HEART RHYTHM TECHNOLOGIES, INC. ,  SHERMAN, Marshall, L. ,  CASTELLANO, Thomas, M. ,  MOYA, Jose, J.

IPC: A61B05/00

CPC classification number: A61B5/01

Abstract: This invention is a system for monitoring temperature comprising a first thermocouple temperature sensor (24) mounted to a catheter (10), the catheter (10) also having a connector with a plurality of connecting devices (38) for making the thermocouple signals available to external equipment. The connecting devices (38) are formed of a material dissimilar to at least one of the thermocouple leads such that a second thermocouple is created at the connection point. The second thermocouple produces a second temperature signal combines with the signal from the first thermocouple. A reference temperature sensor (44) is mounted to the connector (38) to sense the temperature at the connector and provide a reference temperature signal for use by a processor (66) in correcting the combined temperature signal to derive the first thermocouple signal received from the connector.

Abstract translation: 本发明是一种用于监测温度的系统，包括安装在导管（10）上的第一热电偶温度传感器（24），该导管（10）还具有连接器，多个连接装置（38）用于使热电偶信号可用于 外部设备。 连接装置（38）由不同于至少一个热电偶引线的材料形成，使得在连接点处形成第二热电偶。 第二个热电偶产生与第一个热电偶信号相结合的第二个温度信号。 参考温度传感器（44）安装到连接器（38）以感测连接器处的温度，并提供参考温度信号，供处理器（66）用于校正组合温度信号以导出从第一热电偶信号 连接器。