公开(公告)号：WO2019126022A1

公开(公告)日：2019-06-27

申请号：PCT/US2018/065971

申请日：2018-12-17

申请人： BIOSENSE WEBSTER (ISRAEL) LTD. ,  BEECKLER, Christopher, Thomas

发明人： BEECKLER, Christopher, Thomas ,  GOVARI, Assaf

IPC分类号： A61B18/14

CPC分类号： A61B18/1492 ,  A61B5/0422 ,  A61B2017/00199 ,  A61B2017/00526 ,  A61B2018/0022 ,  A61B2018/00226 ,  A61B2018/00327 ,  A61B2018/00351 ,  A61B2018/00357 ,  A61B2018/00375 ,  A61B2018/00434 ,  A61B2018/00577 ,  A61B2018/1405 ,  A61B2018/1465 ,  A61B2018/1467

摘要： A medical instrument includes a shaft, an inflatable balloon and a Radiofrequency (RF) ablation electrode. The shaft is configured for insertion into a body of a patient. The inflatable balloon is coupled to a distal end of the shaft. The RF ablation electrode is disposed on an external surface of the balloon and has a distal edge configured to reduce electric field angular gradients of an RF electric field emitted from the distal edge.

公开(公告)号：WO2019116175A1

公开(公告)日：2019-06-20

申请号：PCT/IB2018/059691

申请日：2018-12-06

申请人： BIOSENSE WEBSTER (ISRAEL) LTD.

发明人： ALTMANN, Andres Claudio ,  GOVARI, Assaf

IPC分类号： A61B18/14 ,  A61B5/042

CPC分类号： A61B18/1492 ,  A61B5/0422 ,  A61B5/6853 ,  A61B5/6857 ,  A61B18/14 ,  A61B90/37 ,  A61B2018/0022 ,  A61B2018/00351 ,  A61B2018/00375 ,  A61B2018/00577 ,  A61B2018/00839 ,  A61B2018/1435 ,  A61M25/0119 ,  A61M25/1002 ,  A61M25/1018 ,  A61M2025/0063 ,  A61M2025/1056

摘要： An apparatus includes a shaft for insertion into a heart, a reverse-lasso catheter disposed at the distal end of the shaft, and multiple sensing-electrodes. The shaft has a distal end and a proximal end. The distal end of the shaft defines a longitudinal axis. The reverse-lasso catheter includes a base segment, and a spiral segment that retrogrades in the proximal direction around the base segment as the spiral segment spirals about the longitudinal axis. The sensing-electrodes are disposed over the spiral segment and are configured to obtain cardio- electrograms.

公开(公告)号：WO2019089199A1

公开(公告)日：2019-05-09

申请号：PCT/US2018/055124

申请日：2018-10-10

申请人： BIOSENSE WEBSTER (ISRAEL) LTD. ,  BEECKLER, Christopher Thomas

发明人： BEECKLER, Christopher Thomas ,  GOVARI, Assaf ,  KEYES, Joseph Thomas ,  HERRERA, Kevin Justin

IPC分类号： A61B5/00 ,  A61B5/042 ,  A61B18/14

CPC分类号： A61B18/1492 ,  A61B5/0422 ,  A61B5/6851 ,  A61B5/6852 ,  A61B5/6856 ,  A61B2017/00243 ,  A61B2017/00292 ,  A61B2018/00351 ,  A61M25/005

摘要： Medical catheterization is carried out by introducing a catheter into a heart, sliding the catheter through a sheath that encloses a multi-electrode probe into a chamber of the heart. The sheath is retracted to expose the probe. As the sheath is retracted the exposed probe expands into a spiral configuration, and the electrodes contact the endocardial surface of the chamber at multiple contact points.

公开(公告)号：WO2019079082A1

公开(公告)日：2019-04-25

申请号：PCT/US2018/055128

申请日：2018-10-10

申请人： BIOSENSE WEBSTER (ISRAEL) LTD. ,  SCHULTZ, Jeffrey

发明人： SCHULTZ, Jeffrey ,  ROUSU, Corey ,  GHIDOLI, Daniele ,  JUNG, Simon ,  CLARK, Jeffrey

IPC分类号： A61M25/01 ,  A61B1/005 ,  A61B17/00

CPC分类号： A61M25/0136 ,  A61B1/0052 ,  A61B5/01 ,  A61B5/0422 ,  A61B5/06 ,  A61B5/6852 ,  A61B5/6869 ,  A61B18/1492 ,  A61B2017/00092 ,  A61B2017/00327 ,  A61B2017/0046 ,  A61B2017/00477 ,  A61B2017/12054 ,  A61B2018/00029 ,  A61B2018/00172 ,  A61B2018/00821 ,  A61B2217/007 ,  A61M25/0147 ,  A61N1/056 ,  A61N1/0565 ,  A61N1/057

摘要： A steerable catheter (10) is disclosed, having an elongated, tubular catheter body (14) with at least one deflection member (30) slidably disposed within a lumen (26, 28), secured at a distal end to a tip section (16) and terminating in an interconnect (46) at a proximal end and a handle (12) releasably attached to the proximal end of the catheter body. The handle has at least one sliding member (54) coupled to an actuator (18), such that manipulation of the actuator causes relative longitudinal movement with respect to the handle, wherein the interconnect and the sliding member engage when the handle is attached to the catheter body so that the relative longitudinal movement of the sliding member is transmitted to the deflection member and wherein the interconnect and the sliding member disengage when the handle is released from the catheter body.

公开(公告)号：WO2019050529A1

公开(公告)日：2019-03-14

申请号：PCT/US2017/050619

申请日：2017-09-08

申请人： MEDICAL COMPONENTS, INC.

发明人： JOYCE, Michael ,  CRUZ, Andres, B., Jr.

IPC分类号： A61B5/02 ,  A61B5/0428 ,  A61B5/044 ,  A61B5/0452

CPC分类号： A61B5/061 ,  A61B5/04012 ,  A61B5/0422 ,  A61B5/0428 ,  A61B5/044 ,  A61B5/0452 ,  A61B5/04525

摘要： A system and method for guiding the placement of a peripherally inserted central catheter in a patient is provided. The system includes a peripherally inserted central catheter; at least one sensor configured to be coupled to said catheter and structured to sense and transmit an electrical signal associated with a P wave; a data base including known data corresponding to standard and non-standard P waves including peaks, deflections and transition points; and a processing device in operable communication with said at least one sensor and said data base, said processing device configured to receive said electrical signal and identify P waveform attributes of said signal, cross-reference said waveform attributes and said electrical signal with known data in said base data, and output indicia representative of said P waveform attributes and said signal based on said cross-reference.

公开(公告)号：WO2018195651A1

公开(公告)日：2018-11-01

申请号：PCT/CA2018/050328

申请日：2018-03-19

申请人： MEDTRONIC CRYOCATH LP

发明人： AVITALL, Boaz

IPC分类号： A61B18/02 ,  A61B5/01 ,  A61B5/042 ,  A61B5/053

CPC分类号： A61B5/01 ,  A61B5/042 ,  A61B5/0422 ,  A61B5/053 ,  A61B5/0536 ,  A61B5/0538 ,  A61B5/6853 ,  A61B18/02 ,  A61B2018/00351 ,  A61B2018/00357 ,  A61B2018/00375 ,  A61B2018/00642 ,  A61B2018/00791 ,  A61B2018/00797 ,  A61B2018/00839 ,  A61B2018/00863 ,  A61B2018/00875 ,  A61B2018/0212 ,  A61B2018/0262 ,  A61B2505/05 ,  A61B2562/046

摘要： A device, system, and method for treating an area of tissue and evaluating lesion formation and quality. The system may include a medical device having a plurality of mapping electrodes on a treatment element, the plurality of mapping electrodes being configured to record from the area of tissue at least one of unipolar impedance measurements, bipolar impedance measurements, local electrical activity, and pace threshold measurements before, during, and after circulation of the cryogenic fluid within the treatment element. These measurements may be transmitted to a control unit having processing circuitry configured to compare pre-treatment measurements, in-treatment measurements, and/or post-treatment measurements to each other and/or to threshold values to determine occlusion and/or lesion quality, such as lesion transmurality.

公开(公告)号：WO2018073722A1

公开(公告)日：2018-04-26

申请号：PCT/IB2017/056404

申请日：2017-10-16

申请人： HOSPITAL CLINIC DE BARCELONA ,  UNIVERSIDAD DE ZARAGOZA ,  UNIVERSITAT POMPEU FABRA

发明人： BERRUEZO SÁNCHEZ, Antonio ,  ALCAINE OTIN, Alejandro ,  MARTÍNEZ CORTÉS, Juan Pablo ,  LAGUNA LASAOSA, Pablo ,  CÁMARA REY, Oscar ,  SOTO IGLESIAS, David

IPC分类号： A61B5/04 ,  A61B5/0452 ,  A61B5/00 ,  A61B5/0408 ,  A61B5/042

CPC分类号： A61B5/0452 ,  A61B5/04017 ,  A61B5/04085 ,  A61B5/0422 ,  A61B5/7246 ,  A61B5/7264 ,  A61B5/7275

摘要： A computer implemented method to identify the ventricular arrhythmogenic substrate in myocardial scar or fibrotic tissue and computer program products A plurality of mapping points acquired from a patient are stored in a signal acquisition unit, said mapping points including a ECG signals, EGM signals and a 3D location of the EGM signals, the method comprising for a reference mapping point: a) detecting each beat present in one recorded ECG signal and identifying a beat of interest from the detected beats; b) identifying a principal EGM wave related to the identified beat of interest; c) identifying an onset and an end time landmarks of said principal EGM wave providing a primary delineated EGM signal and measuring a voltage amplitude of the primary delineated EGM signal; d) performing a further analysis of the primary delineated EGM; and e) creating a conducting channel map and a propagation map of the heart based on the result of a tagging performed during said analysis.

摘要翻译： 用于识别心肌瘢痕或纤维化组织中的心室致心律失常性基质和计算机程序产品的计算机实现的方法将从患者获取的多个映射点存储在信号采集单元中，所述标测点包括 ECG信号，EGM信号和EGM信号的3D位置，所述方法包括：针对参考映射点：a）检测存在于一个记录的ECG信号中的每个拍子，并且从检测到的拍子识别感兴趣的拍子; b）识别与所识别的感兴趣节拍相关的主要EGM波; c）识别所述主要EGM波的开始和结束时间界标，提供主要描述的EGM信号并测量主要描述的EGM信号的电压幅度; d）对主要划定的EGM进行进一步分析; 以及e）基于在所述分析期间执行的标记的结果，创建心脏的传导通道图和传播图。

公开(公告)号：WO2018011632A1

公开(公告)日：2018-01-18

申请号：PCT/IB2017/001040

申请日：2017-07-17

申请人： DRAGON MEDICAL DEVELOPMENT LIMITED

发明人： KEANE, David

IPC分类号： A61B5/042 ,  A61B5/00 ,  A61M25/00 ,  A61B17/00

CPC分类号： A61B5/6858 ,  A61B5/0422 ,  A61B5/6859 ,  A61B2017/00053 ,  A61B2017/00292 ,  A61B2562/0209

摘要： A catheter for mapping the heart simultaneously accommodates a plurality of intravascular devices each having multiple electrode pairs carried on an exterior portion thereof. Each of the of intravascular devices is advancable and retractable relative to the distal end of the tubular catheter body independent of other vascular devices.

摘要翻译： 用于映射心脏的导管同时容纳多个血管内装置，每个血管内装置具有承载在其外部部分上的多个电极对。 每个血管内装置相对于独立于其他血管装置的管状导管本体的远端是可前进和可缩回的。

公开(公告)号：WO2017139340A1

公开(公告)日：2017-08-17

申请号：PCT/US2017/016952

申请日：2017-02-08

申请人： CARDIAC PACEMAKERS, INC.

发明人： MAHAJAN, Deepa ,  PERSCHBACHER, David, L. ,  SHARMA, Arjun, D.

IPC分类号： A61N1/362 ,  A61B5/00

CPC分类号： A61B5/0205 ,  A61B5/0022 ,  A61B5/0024 ,  A61B5/0031 ,  A61B5/021 ,  A61B5/0215 ,  A61B5/0245 ,  A61B5/0422 ,  A61B5/0456 ,  A61B5/046 ,  A61B5/08 ,  A61B5/0816 ,  A61B5/1117 ,  A61B5/686 ,  A61B5/6869 ,  A61B5/7246 ,  A61B5/7282 ,  A61B5/7285 ,  A61B7/02 ,  A61N1/3624 ,  A61N1/36507 ,  A61N1/3956 ,  A61N1/3987 ,  G06F19/00 ,  G16H40/67

摘要： An apparatus includes a sensing circuit configured to generate a sensed physiological signal that includes physiological information of a subject, a detection circuit, and a control circuit. The detection circuit detects a physiological condition of a subject using the physiological signal. The control circuit stores sampled values of a segment of the physiological signal in temporary memory storage; and stores the sampled values in non-temporary storage in response to receiving an indication of continued detection of the physiological condition.

摘要翻译： 一种装置包括感测电路，感测电路被配置为生成感测生理信号，感测生理信号包括对象的生理信息，检测电路和控制电路。 检测电路使用生理信号检测对象的生理状况。 控制电路将生理信号的片段的采样值存储在临时存储器中; 并且响应于接收到持续检测生理状况的指示，将采样值存储在非临时存储器中。

公开(公告)号：WO2017077310A1

公开(公告)日：2017-05-11

申请号：PCT/GB2016/053421

申请日：2016-11-03

申请人： UNIVERSITY OF EXETER

发明人： TERRY, John ,  GREEN, Harry

IPC分类号： A61B5/0464 ,  A61B5/0468 ,  A61B5/00 ,  A61B5/042 ,  A61B5/0402 ,  G06F19/00 ,  A61B18/14 ,  A61B5/046

CPC分类号： A61B5/0464 ,  A61B5/04028 ,  A61B5/0422 ,  A61B5/046 ,  A61B5/0468 ,  A61B5/6856 ,  A61B5/7282 ,  A61B18/1492 ,  A61B2505/05 ,  G06F19/00 ,  G06F19/3481 ,  G16H50/50

摘要： A system adapted to detect one or more conduction gaps in a pulmonary vein of a patient, the system including a device configured to receive or obtain a plurality of pulmonary vein recordings in respect of said patient, each pulmonary vein recording being representative of electrical signals detected or predicted at respective electrodes or between respective pairs of electrodes located or simulated within said pulmonary vein, a device configured to determine a respective activation time for each of said plurality of pulmonary vein recordings and generating curve data representative of said activation times, and a device configured to determine the presence of one or more conduction gaps by identifying one or more respective earliest activation times.

摘要翻译： 适于检测患者的肺静脉中的一个或多个导通间隙的系统，所述系统包括被配置为接收或获得关于所述患者的多个肺静脉记录的装置，每个肺 静脉记录代表在各个电极处或在位于所述肺静脉内或模拟在所述肺静脉内的相应电极对之间检测或预测的电信号，被配置为确定所述多个肺静脉记录中的每一个的相应激活时间的设备， 所述装置被配置为通过识别一个或多个相应的最早激活时间来确定一个或多个导通间隙的存在。