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    CATHETER WITH EXPANDABLE PROBE
    1.
    发明申请
    CATHETER WITH EXPANDABLE PROBE 审中-公开
    具有可扩展探头的导管

    公开(公告)号：WO1996034560A1

    公开(公告)日：1996-11-07

    申请号：PCT/US1996006032

    申请日：1996-05-01

    Applicant: HEART RHYTHM TECHNOLOGIES, INC.

    Inventor： HEART RHYTHM TECHNOLOGIES, INC. ,  JUNG, Eugene, J., Jr. ,  RUSK, Scott, J.

    IPC: A61B05/042

    CPC classification number: A61M25/0136 ,  A61B5/0422 ,  A61B18/1492 ,  A61B2018/00214 ,  A61M25/0147 ,  A61M25/04 ,  A61M2025/015 ,  A61M2025/0188 ,  A61N1/056

    Abstract: This invention is an expandable electrode array (18) mountable to the distal end of a catheter (10). The expandable array includes a plurality of adjacent elongated segments (20) preformed with proximal, medial and distal hinge portions wherein at least one electrode (22) is mounted on at least one of the segments (20). Each of the plurality of peripheral segments (20) is integrally formed with a resilient conductive longitudinal core encapsulated in an electrically insulated material. A deployment mandrel (26) is operatively connected to each of the respective peripheral segments (20) whereby movement of the mandrel (26) in the proximal direction causes the respective peripheral segments (20) to bend outwardly about the proximal, medial and distal hinge portions to radially expand the segments (20) relative to one another so that the electrodes (22) moves to a predetermined transverse coplanar orientation.

    Abstract translation: 本发明是可安装到导管（10）的远端的可扩张电极阵列（18）。 可扩展阵列包括预先形成有近端，内侧和远端铰链部分的多个相邻的细长段（20），其中至少一个电极（22）安装在至少一个段（20）上。 所述多个周边部分（20）中的每一个与封装在电绝缘材料中的弹性导电纵向芯体整体形成。 部署心轴（26）可操作地连接到每个相应的外围段（20），由此心轴（26）沿近侧方向的移动导致相应的周边段（20）围绕近端，内侧和远端铰链向外弯曲 用于相对于彼此径向扩张所述段（20）的部分，使得所述电极（22）移动到预定的横向共面取向。

    INTRACARDIAC ELECTRICAL POTENTIAL REFERENCE CATHETER
    3.
    发明申请
    INTRACARDIAC ELECTRICAL POTENTIAL REFERENCE CATHETER 审中-公开
    电线电位参考电极

    公开(公告)号：WO1993020750A1

    公开(公告)日：1993-10-28

    申请号：PCT/US1993003289

    申请日：1993-04-08

    Applicant: CARDIORHYTHM

    Inventor： CARDIORHYTHM ,  JARACZWESKI, Richard ,  WEST, Scott

    IPC: A61B05/042

    CPC classification number: A61B5/0422 ,  A61B5/6855 ,  A61B2562/0209 ,  A61B2562/043 ,  A61M25/0133 ,  A61M25/0141 ,  A61M2025/0161

    Abstract: An intracardiac electrical potential reference catheter (10) includes a proximal shaft section (14) in a distal flexible tip section (12). The flexible tip section shaped in a geometry suitable for performing intracardiac mapping and includes a plurality of electrodes (24, 26, 28, 30, 34) axially spaced-apart thereon. The shaft section is formed from a polymeric material (41) and includes a reinforcement layer, typically a stainless steel braid (44). The flexible tip section is also formed from a polymeric material (31) and is free from any braided reinforcement. A core wire (70) is attached to a proximal housing (22) on the catheter at one end and to a distal electrode tip (34) at the other end. In this way, the torque is transmitted along the length of the catheter by both the reinforced shaft and separately by the core wire.

    Abstract translation: 心内电位参考导管（10）包括位于远侧柔性末端部分（12）中的近侧轴部分（14）。 所述柔性尖端部分成形为适于执行心脏内映射的几何形状，并且包括在其上轴向间隔开的多个电极（24,26,28,30,34）。 轴部由聚合物材料（41）形成，并且包括加强层，通常为不锈钢编织物（44）。 柔性末端部分也由聚合物材料（31）形成，并且没有任何编织加固件。 芯线（70）在一端附接到导管上的近端壳体（22）并且在另一端附接到远端电极尖端（34）。 以这种方式，扭矩通过加强轴和芯线单独地沿着导管的长度传递。

    SHEATHED MULTIPOLAR CATHETER AND MULTIPOLAR GUIDEWIRE FOR SENSING CARDIAC ELECTRICAL ACTIVITY
    4.
    发明申请
    SHEATHED MULTIPOLAR CATHETER AND MULTIPOLAR GUIDEWIRE FOR SENSING CARDIAC ELECTRICAL ACTIVITY 审中-公开
    用于传感心脏电活动的多用途导管和多功能导针

    公开(公告)号：WO1995009561A1

    公开(公告)日：1995-04-13

    申请号：PCT/US1994011115

    申请日：1994-09-30

    Applicant: TARGET THERAPEUTICS, INC.

    Inventor： TARGET THERAPEUTICS, INC. ,  SAMSON, Gene ,  VEGH, Gabriel, B. ,  DICKENS, Duane ,  RETTKE, Herbert, G.

    IPC: A61B05/042

    CPC classification number: A61B5/6851 ,  A61B5/0422

    Abstract: This invention is a medical device. It is a multipolar catheter assembly (100) optionally in combination with a guidewire (300). Each of the catheter (100) and the guidewire (300) may be sheathed and have multiple electrodes (114, 306) at their distal ends (102, 322). Because of their size and flexibility, the catheter (100) and the guidewire (300), may be used at virtually any point within the vasculature particularly, however, within the cardiac arteries or veins, perhaps in conjunction with external electrocardiogram leads, tomap the body's electrical activity. When used in the heart, they may be used to determine the source of cardiac arrythmia. The intimate presence of the guidewire (300) or catheter (100) body in the cardiac vasculature allows the response time to changes in cardiac electrical activity to be very quick. The invention is also a method for mapping the electrical activity of the heart by use of one or more of these inventive guidewires (300) or catheters (100) in the cardiac arteries or veins. They may also be used to determine the local electrical activity of any site within the body, such as in the brain.

    Abstract translation: 本发明是医疗装置。 它是可选地与导丝（300）组合的多极导管组件（100）。 导管（100）和导丝（300）中的每一个可以被包覆并且在其远端（102,322）处具有多个电极（114,306）。 由于其尺寸和柔性，导管（100）和导丝（300）可以在脉管系统中的几乎任何点处使用，特别是在心脏动脉或静脉内，或许与外部心电图引导相结合 身体的电活动。 当用于心脏时，它们可用于确定心脏性心律失常的来源。 导管（300）或导管（100）主体在心脏血管系统中的紧密存在使得心脏电活动的响应时间变得非常快。 本发明还是通过使用心脏动脉或静脉中的这些创造性导线（300）或导管（100）中的一个或多个来映射心脏的电活动的方法。 它们也可用于确定体内任何部位的局部电活动，例如在脑中。

    SYSTEM AND METHOD FOR ANALYZING ELECTROGRAM WAVEFORMS
    6.
    发明申请
    SYSTEM AND METHOD FOR ANALYZING ELECTROGRAM WAVEFORMS 审中-公开
    用于分析电子波形的系统和方法

    公开(公告)号：WO1997017893A1

    公开(公告)日：1997-05-22

    申请号：PCT/US1996017676

    申请日：1996-11-12

    Applicant: HEART RHYTHM TECHNOLOGIES, INC.

    Inventor： HEART RHYTHM TECHNOLOGIES, INC. ,  PAISNER, William, Lee

    IPC: A61B05/042

    CPC classification number: A61B5/6852 ,  A61B5/0422

    Abstract: An electrogram analysis system and method for determining the quality of information gathered from electrical signals in biological tissue. The system comprises a catheter (14) having an array (16) of at least two electrodes (18) at its distal end, the electrodes (18) detecting electrical signals to a processor (28). The processor (28) processes the relayed signals into waveforms and computes a quality of the relayed signals. The quality of the relayed signals is used to select higher quality signals for further analysis, such as site of origin determination and mapping. The relayed signals from the electrodes (18) may also be used to determine a quality for a particular electrode channel. When the invention is used in cardiac applications, the relayed signal quality may comprise two components - a channel quality and a beat quality. The channel quality represents the value of information received from a particular electrode and channel, while the beat quality represents the value of a particular heart beat across all channels. The signal quality is displayed to the user. In cardiac applications, the channel quality can be displayed (34) in a format corresponding to the shape of the electrode array, with channel quality from each electrode positioned in a corresponding position on the display (30). The display (30) may also show the waveforms of the signal, such as the heart beat waveform (32) in a cardiac procedure.

    Abstract translation: 一种用于确定从生物组织中的电信号收集的信息的质量的电描记图分析系统和方法。 该系统包括在其远端具有至少两个电极（18）的阵列（16）的导管（14），电极（18）检测到处理器（28）的电信号。 处理器（28）将中继的信号处理成波形并计算中继信号的质量。 中继信号的质量用于选择较高质量的信号进行进一步分析，如原点确定和映射。 来自电极（18）的中继信号也可用于确定特定电极通道的质量。 当本发明用于心脏应用时，中继信号质量可以包括两个组件 - 信道质量和节拍质量。 信道质量表示从特定电极和信道接收的信息的值，而节拍质量表示所有信道上的特定心跳的值。 信号质量显示给用户。 在心脏应用中，可以以对应于电极阵列的形状的格式显示（34）通道质量，其中来自每个电极的通道质量位于显示器（30）上的对应位置。 显示器（30）还可以显示心脏过程中的诸如心跳波形（32）的信号的波形。

    HIGH RESOLUTION INTRAVASCULAR SIGNAL DETECTION
    8.
    发明申请
    HIGH RESOLUTION INTRAVASCULAR SIGNAL DETECTION 审中-公开
    高分辨率血管内信号检测

    公开(公告)号：WO1996036277A1

    公开(公告)日：1996-11-21

    申请号：PCT/US1996006631

    申请日：1996-05-08

    Applicant: CARDIMA, INC.

    Inventor： CARDIMA, INC. ,  LITTMANN, Laszlo ,  LAU, Liming ,  AMIRANA, Omar

    IPC: A61B05/042

    CPC classification number: A61B17/12022 ,  A61B5/0422 ,  A61B17/22012 ,  A61B18/14 ,  A61B2017/00022 ,  A61B2017/00026 ,  A61B2017/00243 ,  A61B2562/0209 ,  A61B2562/043

    Abstract: A system for detecting electrical activity within a patient's heart comprising an elongated intravascular device (10), such as a catheter or guidewire, having a plurality of sensing electrodes (16) on a distal section of the elongated device to detect electrical activity from within a blood vessel of the patient's heart. The intravascular device has a first compact array (17) with a relatively small interelectrode spacing, such as less than 2 mm, and may have a second electrode array (20) with an interelectrode spacing much greater than the interelectrode spacing in the first array. The second electrode array may be used to detect the general region of the arrhythmogenic tissue and the first electrode array is used to provide a high resolution of the electrical detection to more accurately pinpoint the location of the arrhythmogenic site. When the general region of the arrhythmogenic focus is known, an intravascular device having a single array of electrodes with an interelectrode spacing of less than 2 mm may be used.

    Abstract translation: 一种用于检测患者心脏内的电活动的系统，包括细长的血管内装置（10），例如导管或导丝，其具有在细长装置的远端部分上的多个感测电极（16），以检测电活动 患者心脏的血管 血管内装置具有第一紧凑阵列（17），其具有相对小的电极间间隔，例如小于2mm，并且可以具有第二电极阵列（20），其间的电极间距远远大于第一阵列中的电极间间隔。 第二电极阵列可用于检测致心律失常组织的一般区域，并且第一电极阵列用于提供电检测的高分辨率以更精确地确定致心律失常部位的位置。 当已知致心律失常焦点的一般区域时，可以使用具有电极间距小于2mm的单个电极阵列的血管内装置。

    METHOD INTRAVASCULAR SENSING DEVICES FOR ELECTRICAL ACTIVITY
    9.
    发明申请
    METHOD INTRAVASCULAR SENSING DEVICES FOR ELECTRICAL ACTIVITY 审中-公开
    方法用于电活动的静脉感测装置

    公开(公告)号：WO1994016619A1

    公开(公告)日：1994-08-04

    申请号：PCT/US1994001055

    申请日：1994-01-28

    Applicant: CARDIMA, INC.

    Inventor： CARDIMA, INC. ,  LITTMAN, Laszlo ,  DICKENS, Duane

    IPC: A61B05/042

    CPC classification number: A61B17/12022 ,  A61B5/02007 ,  A61B5/0422 ,  A61B5/6852 ,  A61B17/12109 ,  A61B17/12145 ,  A61B17/1215 ,  A61B17/12163 ,  A61B17/22012 ,  A61B18/14 ,  A61B2017/00022 ,  A61B2017/00026 ,  A61B2017/00243 ,  A61B2017/1205 ,  A61B2017/12063 ,  A61B2562/0209 ,  A61B2562/043

    Abstract: A method and system for detecting electrical activity within a patient's heart, particularly the electrical activity which causes arrhythmia, which includes a first intravascular device (40) such as a catheter or guidewire having a plurality of sensing electrodes (15) on a distal portion (14) thereof which is disposed within one location of the patient's coronary vasculature and a second intravascular device (11) such as a catheter or guidewire having a plurality of sensing electrodes (17) on a distal portion (16) thereof which is disposed within a second location of the patient's coronary vasculature to facilitate mapping the electrical activity of the patient's heart. Once the electrical activity has been mapped, therapeutic procedures can be initiated.

    Abstract translation: 一种用于检测患者心脏内的电活动的方法和系统，特别是导致心律失常的电活动，其包括第一血管内装置（40），例如在远侧部分上具有多个感测电极（15）的导管或导丝（ 其设置在患者的冠状动脉脉管系统的一个位置内，以及第二血管内装置（11），例如导管或导丝，其在远侧部分（16）上具有多个感测电极（17） 患者冠状动脉脉管系统的第二位置以便于映射患者心脏的电活动。 一旦映射了电活动，就可以启动治疗程序。

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