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公开(公告)号：WO2013087945A2
公开(公告)日：2013-06-20
申请号：PCT/EP2013/054227
申请日：2013-03-02
Applicant: NOVARTIS AG
Inventor： SUPHAPHIPHAT, Pirada , MASON, Peter , KEINER, Bjoern , DORMITZER, Philip, Ralph , TRUSHEIM, Heidi
IPC: C12N7/00
CPC classification number: A61K39/145 , A61K2039/525 , A61K2039/5252 , C07K14/005 , C12N7/00 , C12N2760/16121 , C12N2760/16122 , C12N2760/16134 , C12N2760/16151 , C12N2760/16161
Abstract: New influenza donor strains for the production of reassortant influenza A viruses are provided.
Abstract translation: 提供用于产生重配甲型流感病毒的新的流感供体菌株。
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公开(公告)号：WO2014141125A3
公开(公告)日：2014-09-18
申请号：PCT/IB2014/059729
申请日：2014-03-13
Applicant: NOVARTIS AG , SYNTHETIC GENOMICS VACCINES, INC.
Inventor： DORMITZER, Philip , MASON, Peter , SUPHAPHIPHAT, Pirada , GOMILA, Raul
IPC: A61K39/12
Abstract: New influenza donor strains for the production of reassortant influenza B viruses are provided.
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公开(公告)号：WO2010133964A1
公开(公告)日：2010-11-25
申请号：PCT/IB2010/001332
申请日：2010-05-21
Applicant: NOVARTIS AG , DORMITZER, Philip , FRANTI, Michael , SUPHAPHIPHAT, Pirada , MASON, Peter , KEINER, Bjoern , CROTTA, Stephania
Inventor： DORMITZER, Philip , FRANTI, Michael , SUPHAPHIPHAT, Pirada , MASON, Peter , KEINER, Bjoern , CROTTA, Stephania
IPC: C12N15/85
CPC classification number: C12N15/86 , A61K39/12 , A61K39/145 , C12N7/00 , C12N15/85 , C12N2760/16021 , C12N2760/16034 , C12N2760/16043 , C12N2760/16052 , C12N2760/16134 , C12N2760/16234 , C12N2830/00 , C12N2830/85
Abstract: Expression of a transgene is driven in a host cell using a pol I promoter which is not endogenous to an organism from the same taxonomic order from which the host cell is derived.
Abstract translation: 转基因的表达在宿主细胞中使用来自与宿主细胞相同的分类顺序的生物体不是内源的pol I启动子来驱动。
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公开(公告)号：WO2015158927A1
公开(公告)日：2015-10-22
申请号：PCT/EP2015/058533
申请日：2015-04-20
Applicant: NOVARTIS AG
Inventor： HO, Samuel , PARKER, David , FEKKES, Peter , DE SOUZA, Ivna , MASON, Peter , SUPHAPHIPHAT, Pirada
IPC: A61K39/12 , A61K39/145
CPC classification number: C07K14/005 , A61K39/00 , A61K39/12 , A61K2039/575 , C12N7/00 , C12N2760/16111 , C12N2760/16134 , C12N2760/16143 , C12N2760/16151 , C12N2760/16234 , C12N2760/16243 , C12N2760/16251
Abstract: Disclosed herein are methods for increasing protein yield and cellular productivity. Chemical agents facilitate host cell production of biological molecules to increase product yield.
Abstract translation: 本文公开了提高蛋白质产量和细胞生产率的方法。 化学试剂促进生物分子的宿主细胞生成以提高产物产率。
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Patent Agency Ranking
公开(公告)号：WO2014086732A8
公开(公告)日：2014-06-12
申请号：PCT/EP2013/075294
申请日：2013-12-02
Applicant: NOVARTIS AG , SYNTHETIC GENOMICS VACCINES, INC.
Inventor： MASON, Peter , DORMITZER, Philip Ralph , TRUSHEIM, Heidi , SUPHAPHIPHAT, Pirada
IPC: A61K39/145
Abstract: New influenza donor strains for the production of reassortant influenza A viruses are provided.
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公开(公告)号：WO2014086732A2
公开(公告)日：2014-06-12
申请号：PCT/EP2013/075294
申请日：2013-12-02
Applicant: NOVARTIS AG , SYNTHETIC GENOMICS VACCINES, INC.
Inventor： MASON, Peter , DORMITZER, Philip Ralph , TRUSHEIM, Heidi , SUPHAPHIPHAT, Pirada
IPC: A61K39/145
CPC classification number: A61K39/145 , A61K39/12 , A61K2039/5252 , C12N7/00 , C12N2760/16121 , C12N2760/16134 , C12N2760/16151 , C12N2760/16152
Abstract: New influenza donor strains for the production of reassortant influenza A viruses are provided.
Abstract translation: 提供用于产生重配甲型流感病毒的新的流感供体菌株。
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公开(公告)号：WO2014195920A3
公开(公告)日：2014-12-11
申请号：PCT/IB2014/062030
申请日：2014-06-06
Applicant: NOVARTIS AG , SYNTHETIC GENOMICS VACCINES, INC.
Inventor： MASON, Peter , SUPHAPHIPHAT, Pirada , GOMILA, Raul , DORMITZER, Philip
IPC: C12N7/00 , A61K39/145 , A61K39/12
Abstract: The invention provides reassortant influenza strains.
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公开(公告)号：WO2014115104A1
公开(公告)日：2014-07-31
申请号：PCT/IB2014/058501
申请日：2014-01-23
Applicant: NOVARTIS AG , SYNTHETIC GENOMICS VACCINES, INC.
Inventor： DORMITZER, Philip , MASON, Peter , SUPHAPHIPHAT, Pirada , GIBSON, Daniel , WENTWORTH, David , STOCKWELL, Timothy , GLASS, John
IPC: A61K39/145 , C07K14/11 , C12N15/85 , A61K39/00
CPC classification number: A61K39/145 , A61K39/12 , A61K2039/5254 , C07K14/11 , C12N15/85 , C12N2760/16134 , C12N2760/16151 , C12N2760/16234 , C12N2760/16251 , C12N2800/24
Abstract: Improved methods for the production of reassortant influenza viruses are provided.
Abstract translation: 提供了用于生产重配流感病毒的改进方法。
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公开(公告)号：WO2011048560A1
公开(公告)日：2011-04-28
申请号：PCT/IB2010/054752
申请日：2010-10-20
Applicant: NOVARTIS AG , DORMITZER, Philip , KEINER, Björn , SUPHAPHIPHAT, Pirada , FRANTI, Michael , MASON, Peter , UHLENDORFF, Jennifer , MATROSOVICH, Mikhail
Inventor： DORMITZER, Philip , KEINER, Björn , SUPHAPHIPHAT, Pirada , FRANTI, Michael , MASON, Peter , UHLENDORFF, Jennifer , MATROSOVICH, Mikhail
IPC: C12N7/02
CPC classification number: C12N7/00 , A61K39/12 , A61K2039/525 , A61K2039/5252 , C12N2760/16151
Abstract: A method for rescuing a virus by reverse genetics is provided in which cells are added after transfection.
Abstract translation: 提供了通过反向遗传学拯救病毒的方法，其中在转染后添加细胞。
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