公开(公告)号：WO2009039044A1

公开(公告)日：2009-03-26

申请号：PCT/US2008/076277

申请日：2008-09-12

Applicant: MINASSIANS, Nastaran

Inventor： MINASSIANS, Nastaran

IPC: F15B7/10

CPC classification number: A61B5/150992 ,  A61B5/15003 ,  A61B5/150236 ,  A61B5/150244 ,  A61B5/150351 ,  A61B5/150908 ,  A61B5/153 ,  A61B10/007 ,  A61M2005/3121 ,  A61M2005/3217 ,  B01L3/5635 ,  B01L2200/025

Abstract: A closed specimen collection system for urine includes a port tube with a one-way valve adapted to fit a shaped nozzle that is attached to tubing ofto an indwelling urinary catheter A collection tube has a shaped nozzle at the proximal end adapted to fit sealably into the port tube adjacent the one-way valve. A specimen collection system for blood samples includes a collection tube that has a shaped nozzle adapted to fit sealably into a port connected to a centrally inserted venal catheter. Both versions use a specimen container with a hollow body, a front end with a sealable aperture that attaches to the end of the collection tube A piston fits closely within the hollow body and is attached to an actuating rod. When the actuating rod is retracted, urine or blood will flow into the specimen container through the collection tube in a sterile condition.

Abstract translation: 用于尿的封闭样本收集系统包括具有单向阀的端口管，该单向阀适于安装连接到留置导尿管的管的成形喷嘴。收集管在近端具有适于密封地配合的成形喷嘴 端口管邻近单向阀。 用于血液样本的样本收集系统包括收集管，该收集管具有适于可密封地配合到连接到中心插入的静脉导管的端口中的成形喷嘴。 两种版本都使用具有中空体的标本容器，具有附着到收集管A端部的可密封孔的前端活塞紧密地配合在中空体内并附接到致动杆。 当致动杆缩回时，尿液或血液将在无菌状态下通过收集管流入样本容器。

公开(公告)号：WO2009036105A2

公开(公告)日：2009-03-19

申请号：PCT/US2008075915

申请日：2008-09-11

Applicant: BAXTER INT ,  BAXTER HEALTHCARE SA ,  KRISHNAMOORTHY SIVARAMAKRISHNA ,  NIU SANJUN ,  LAL BIRENDRA K ,  BUI TUAN ,  MEINZER RANDOLPH R

Inventor： KRISHNAMOORTHY SIVARAMAKRISHNAN ,  NIU SANJUN ,  LAL BIRENDRA K ,  BUI TUAN ,  MEINZER RANDOLPH R

IPC: A61B5/026

CPC classification number: A61M5/14212 ,  A61B5/14532 ,  A61B5/1459 ,  A61B5/1473 ,  A61B5/15003 ,  A61B5/150099 ,  A61B5/150213 ,  A61B5/150221 ,  A61B5/150229 ,  A61B5/150236 ,  A61B5/150244 ,  A61B5/150389 ,  A61B5/150503 ,  A61B5/150755 ,  A61B5/15087 ,  A61B5/150992 ,  A61B5/153 ,  A61B5/155 ,  A61B5/157 ,  A61B5/4839 ,  A61M5/1723 ,  A61M25/007 ,  A61M2205/3303 ,  A61M2205/3306 ,  A61M2205/3313

Abstract: A sensor system for use with an infusion system may include at least one sensor disposed within a catheter, the at least one sensor comprising at least one of an optical sensor, an electrical sensor or a chemical/biochemical sensor. The sensor system may instead include a sample cell that is in fluid communication with the infusion system, which sample cell may be used with an analyzer to determine a patient's condition. The sensor system may be integrated with a control system for an infusion pump to control operation of the pump.

Abstract translation: 用于输注系统的传感器系统可以包括设置在导管内的至少一个传感器，所述至少一个传感器包括光学传感器，电传感器或化学/生物化学传感器中的至少一个。 传感器系统可以替代地包括与输注系统流体连通的样品池，该样品池可以与分析仪一起使用以确定患者的状况。 传感器系统可以与用于输注泵的控制系统集成以控制泵的操作。

公开(公告)号：WO2006033715A3

公开(公告)日：2008-11-13

申请号：PCT/US2005028141

申请日：2005-08-09

Applicant: BIOANALYTICAL SYSTEMS INC ,  KISSINGER CANDICE B

Inventor： KISSINGER CANDICE B

IPC: A61B5/00 ,  A01K1/03

CPC classification number: A61B5/1113 ,  A61B5/15003 ,  A61B5/150221 ,  A61B5/150229 ,  A61B5/150236 ,  A61B5/150244 ,  A61B5/150305 ,  A61B5/150366 ,  A61B5/150755 ,  A61B5/150809 ,  A61B5/150824 ,  A61B5/150862 ,  A61B5/150992 ,  A61B5/153 ,  A61B5/154 ,  A61B5/157 ,  A61B2503/045 ,  A61B2503/40 ,  A61B2560/0437

Abstract: A portable sampling or testing device for pharmacokinetics and physiology studies and a method for using the device in conducting tests on stationary or moving animals, or human test subjects, is disclosed. The device includes an apparatus for conducting a test on a freely moving subject, or a device which may be moved by a technician to be positioned over an immobile subject, such as a premature infant or unconscious human subject in an intensive care ward. The device is designed and sized to be mobile. The device may include an uninterruptible power supply. The method provides for sampling bodily fluids or acquiring physiological readings from the test subject. The method provides for removal of body fluids with or without reintroduction of the withdrawn bodily fluids back into the freely moving subject.

Abstract translation: 公开了用于药物动力学和生理学研究的便携式取样或测试装置以及使用该装置对静止或移动动物或人体测试对象进行测试的方法。 该装置包括用于对自由移动的受试者进行测试的装置，或可由技术人员移动以定位在不可移动的对象上的装置，例如在重症监护病房中的早产儿或无意识的人类受试者。 该设备的设计和尺寸是可移动的。 该设备可以包括不间断电源。 该方法提供体液取样或从测试对象获取生理学读数。 该方法提供用或不将引回的体液重新引入自由移动的受试者中去除体液。

公开(公告)号：WO2008077047A3

公开(公告)日：2008-10-02

申请号：PCT/US2007087951

申请日：2007-12-18

Applicant: PATTON RICHARD G

Inventor： PATTON RICHARD G

IPC: A61M5/178

CPC classification number: A61B5/150343 ,  A61B5/1422 ,  A61B5/1438 ,  A61B5/15003 ,  A61B5/150099 ,  A61B5/150221 ,  A61B5/150251 ,  A61B5/150389 ,  A61B5/150473 ,  A61B5/150503 ,  A61B5/150755 ,  A61B5/150977 ,  A61B5/150992 ,  A61B5/153 ,  A61B5/154 ,  A61B5/1545 ,  A61B5/155 ,  A61B10/0045 ,  A61B10/0048 ,  A61B10/0051 ,  A61B10/007 ,  A61B10/0096 ,  A61B10/0233 ,  A61B2010/0061 ,  A61B2010/0077 ,  B01L3/502 ,  B01L2200/026 ,  B01L2200/141 ,  B01L2300/0672 ,  B01L2400/082

Abstract: The present invention is directed to the parenteral procurement of bodily-fluid samples. The present invention is also directed to systems and methods for parenterally procuring bodily-fluid samples with reduced contamination from dermally-residing microbes. In some embodiments, a bodily-fluid withdrawing system is used to withdraw bodily fluid from a patient for incubation in culture media in one or more sample vessels. Prior to withdrawing bodily fluid into the one or more sample vessels for incubation, an initial volume of withdrawn bodily fluid is placed in one or more pre-sample reservoirs and is not used for the incubation in culture media.

Abstract translation: 本发明涉及体液样品的肠胃外采购。 本发明还涉及用于肠胃外采集体液样品的系统和方法，其减少了来自皮肤驻留微生物的污染。 在一些实施例中，使用体液抽取系统来从患者抽取体液以在一个或多个样本器皿中的培养基中孵育。 在将体液抽出到一个或多个样品容器中进行温育之前，将抽出的体液的初始体积放置在一个或多个样品前储液器中并且不用于在培养基中温育。

公开(公告)号：WO2007137285A3

公开(公告)日：2008-08-14

申请号：PCT/US2007069542

申请日：2007-05-23

Applicant: INTELLIDX ,  GOLDBERGER DANIEL ,  SHREVE ERIC ,  SIEBRECHT WAYNE ,  PESACH BENNY ,  PESACH GIDI ,  BITTON GABBY ,  NAGAR RON ,  ARGAMAN DALIA ,  BELLOMO STEPHEN ,  LARSON ROBERT ,  JOHNSON LARRY ,  KLOMHAUS JILL

Inventor： GOLDBERGER DANIEL ,  SHREVE ERIC ,  SIEBRECHT WAYNE ,  PESACH BENNY ,  PESACH GIDI ,  BITTON GABBY ,  NAGAR RON ,  ARGAMAN DALIA ,  BELLOMO STEPHEN ,  LARSON ROBERT ,  JOHNSON LARRY ,  KLOMHAUS JILL

IPC: A61B5/00 ,  B65D81/00

CPC classification number: A61B5/14532 ,  A61B5/1486 ,  A61B5/15003 ,  A61B5/150221 ,  A61B5/150229 ,  A61B5/150236 ,  A61B5/150358 ,  A61B5/150412 ,  A61B5/150503 ,  A61B5/15087 ,  A61B5/150992 ,  A61B5/155 ,  A61B5/157 ,  A61B2562/0295

Abstract: The present invention relates generally to systems, apparatuses, and methods for obtaining a fluid sample from a patient. In particular, the present invention relates to a various types of fluid access interfaces for enabling contact between a patient blood sample and blood parameter sensors for the measurement of physiological parameters and blood constituents.

Abstract translation: 本发明一般涉及从患者获得流体样本的系统，装置和方法。 特别地，本发明涉及用于使患者血液样本和血液参数传感器之间的接触用于测量生理参数和血液成分的各种类型的流体存取界面。

公开(公告)号：WO2008077047A2

公开(公告)日：2008-06-26

申请号：PCT/US2007/087951

申请日：2007-12-18

Applicant: PATTON, Richard, G.

Inventor： PATTON, Richard, G.

IPC: A61M5/178

CPC classification number: A61B5/150343 ,  A61B5/1422 ,  A61B5/1438 ,  A61B5/15003 ,  A61B5/150099 ,  A61B5/150221 ,  A61B5/150251 ,  A61B5/150389 ,  A61B5/150473 ,  A61B5/150503 ,  A61B5/150755 ,  A61B5/150977 ,  A61B5/150992 ,  A61B5/153 ,  A61B5/154 ,  A61B5/1545 ,  A61B5/155 ,  A61B10/0045 ,  A61B10/0048 ,  A61B10/0051 ,  A61B10/007 ,  A61B10/0096 ,  A61B10/0233 ,  A61B2010/0061 ,  A61B2010/0077 ,  B01L3/502 ,  B01L2200/026 ,  B01L2200/141 ,  B01L2300/0672 ,  B01L2400/082

Abstract: The present invention is directed to the parenteral procurement of bodily-fluid samples. The present invention is also directed to systems and methods for parenterally procuring bodily-fluid samples with reduced contamination from dermally-residing microbes. In some embodiments, a bodily-fluid withdrawing system is used to withdraw bodily fluid from a patient for incubation in culture media in one or more sample vessels. Prior to withdrawing bodily fluid into the one or more sample vessels for incubation, an initial volume of withdrawn bodily fluid is placed in one or more pre-sample reservoirs and is not used for the incubation in culture media.

Abstract translation: 本发明涉及体外流体样品的肠胃外采购。 本发明还涉及用于肠胃外采购具有减少来自真皮微生物的微生物污染的体液样品的系统和方法。 在一些实施例中，身体流体抽出系统用于从患者体内取出体液以在一个或多个样品容器中的培养基中孵育。 在将体液抽出到一个或多个用于孵育的样品容器之前，将撤回的体液的初始体积放置在一个或多个预样品储存器中，并且不用于在培养基中孵育。

公开(公告)号：WO2008037316A2

公开(公告)日：2008-04-03

申请号：PCT/EP2007/006784

申请日：2007-07-31

Applicant: REGITTNIG, Werner

IPC: A61B5/145 ,  A61B5/1495

CPC classification number: A61B5/157 ,  A61B5/14525 ,  A61B5/14528 ,  A61B5/14532 ,  A61B5/14865 ,  A61B5/150022 ,  A61B5/150229 ,  A61B5/150358 ,  A61B5/150389 ,  A61B5/150511 ,  A61B5/150519 ,  A61B5/150992 ,  A61B5/15105 ,  A61B5/15142 ,  A61B5/155 ,  A61B5/4839 ,  A61B5/6852 ,  A61B5/686 ,  A61M5/1723 ,  A61M2005/1726 ,  A61M2230/201 ,  G06F19/00

Abstract: A device for determining a value of a physiological parameter of a body fluid of a body under investigation, the device comprising a fluid reservoir for containing a perfusate fluid, a body interface insertable into the body under investigation for a fluid communication between the fluid reservoir and the body fluid, a fluid conduit between the fluid reservoir and the body interface, a bidirectional fluid transport unit for transporting the perfusate fluid from the fluid reservoir through the fluid conduit and the body interface into the body under investigation and for subsequently transporting a mixture of the perfusate fluid and the body fluid from the body under investigation through the body interface into the fluid conduit, and a sensor for sensing the value of the physiological parameter based on an analysis of the mixture of the perfusate fluid and the body fluid.

Abstract translation: 用于确定正在研究的身体的体液的生理参数的值的装置，所述装置包括用于容纳灌注液的液体储存器，可在研究中插入身体中的身体接口， 流体贮存器和体液之间的流体连通，流体贮存器和身体接口之间的流体导管，双向流体输送单元，用于将灌注液从流体贮存器通过流体导管和身体接口输送到体内的体内 调查并随后将来自身体流体的灌注液和体液的混合物通过身体接口输送到流体导管中的传感器以及用于基于对灌注液的混合物的分析来感测生理参数的值的传感器 液体和体液。

公开(公告)号：WO2007052255A3

公开(公告)日：2007-11-01

申请号：PCT/IL2006001237

申请日：2006-10-26

Applicant: FENSTER MARK ,  KABIRI ILAN

Inventor： FENSTER MARK ,  KABIRI ILAN

IPC: A61B5/00 ,  A61B5/155 ,  A61M1/00

CPC classification number: A61M39/0247 ,  A61B5/14528 ,  A61B5/14532 ,  A61B5/14552 ,  A61B5/14557 ,  A61B5/15003 ,  A61B5/150221 ,  A61B5/150229 ,  A61B5/150358 ,  A61B5/150389 ,  A61B5/150503 ,  A61B5/150755 ,  A61B5/150862 ,  A61B5/150992 ,  A61B5/1535 ,  A61B5/155 ,  A61B5/4839 ,  A61B5/6848 ,  A61B5/686 ,  A61B5/6865 ,  A61B5/6876 ,  A61B5/6884 ,  A61M5/1723 ,  A61M2005/1726 ,  A61M2039/0258 ,  A61M2039/0267 ,  A61M2039/0276 ,  A61M2039/0279 ,  A61M2205/3313

Abstract: A system for continuous measurement of a blood characteristic comprising: an arterial venal shunt, at least a portion of which appears externally to a subject, the arterial venal shunt arranged to carry blood of the subject; at least one of a spectral measurer and a contact measurer operable on the blood within the externally appearing portion; a computing device receiving an output of the at least one of a spectral measurement means and a contact measurement means; and an injection device responsive to an output of the computing device, the injection device being operable to inject a pharmaceutical from a pharmaceutical reservoir, wherein the computing device responsive to the output of the at least one of a spectral measurer and a contact measurer is operable to output a signal to the injection device, the injection device being operable to inject a measured amount of pharmaceutical responsive to the signal.

Abstract translation: 一种用于连续测量血液特征的系统，其特征在于包括：主动脉分流，其至少一部分出现在受试者的外部，所述动脉静脉分路布置成携带受试者的血液; 光谱测量器和接触测量器中的至少一个可在外部出现部分内的血液上操作; 接收光谱测量装置和接触测量装置中的至少一个的输出的计算装置; 以及响应于所述计算装置的输出的注射装置，所述注射装置可操作以从药物储存器注射药物，其中所述计算装置响应于所述光谱测量器和接触测量器中的至少一个的输出是可操作的 为了向注射装置输出信号，注射装置可操作以响应于该信号注入测量量的药物。

公开(公告)号：WO2007002209A2

公开(公告)日：2007-01-04

申请号：PCT/US2006024167

申请日：2006-06-20

Applicant: GLUCON INC ,  GOLDBERGER DANIEL ,  SHREVE ERIC ,  SIEBRECHT WAYNE ,  PESACH BENNY ,  PESACH GIDI ,  BITTON GABBY ,  NAGAR RON

Inventor： GOLDBERGER DANIEL ,  SHREVE ERIC ,  SIEBRECHT WAYNE ,  PESACH BENNY ,  PESACH GIDI ,  BITTON GABBY ,  NAGAR RON

IPC: A61B5/05

CPC classification number: A61B5/155 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/15003 ,  A61B5/150221 ,  A61B5/150229 ,  A61B5/150305 ,  A61B5/150358 ,  A61B5/15087 ,  A61B5/150992 ,  A61B5/153 ,  A61B5/157 ,  A61B5/6866

Abstract: A substantially automatic blood parameter testing apparatus for obtaining a blood sample and determining the concentration of at least one analyte is connected to a venous or arterial access line and further comprises a pump fixedly attached to a tube originating from the vascular access point; a valve fixedly attached to the tube and located above the pump mechanism; at least one measurement element; a needleless port; and an electronic meter. In addition, the automated blood parameter testing apparatus may be integrated into a complete system, further including a monitor and a central monitoring station.

Abstract translation: 用于获得血液样本和确定至少一种分析物的浓度的基本上自动的血液参数测试设备连接到静脉或动脉接入线路并且还包括固定地连接到源自血管接入点的管的泵; 固定地连接到所述管并位于所述泵机构上方的阀; 至少一个测量元件; 一个无针的港口; 和一个电子仪表。 另外，自动化血液参数测试装置可以集成到完整的系统中，还包括监测器和中央监测站。

公开(公告)号：WO2006126002A1

公开(公告)日：2006-11-30

申请号：PCT/GB2006/001933

申请日：2006-05-25

Applicant: PA KNOWLEDGE LIMITED ,  OWEN, Richard, Harley, Grenville ,  BLATCHER, Stephen ,  FOX, Stewart, Maddison ,  HUGHES, Martin, Lawrence

Inventor： OWEN, Richard, Harley, Grenville ,  BLATCHER, Stephen ,  FOX, Stewart, Maddison ,  HUGHES, Martin, Lawrence

IPC: A61B5/00 ,  A61B10/00

CPC classification number: A61B1/00094 ,  A61B5/15003 ,  A61B5/150236 ,  A61B5/150992 ,  A61B5/153 ,  A61B5/154 ,  A61M25/0071 ,  A61M2025/0008

Abstract: A catheter for insertion into a blood vessel, the catheter having a sampling part (6) arranged to capture a blood sample at a plurality of locations along a length of the blood vessel and an apparatus arranged to analyse blood taken from a plurality of locations along the length of the blood vessel and to provide a profile of concentration levels along the length of the blood vessel.

Abstract translation: 一种用于插入血管的导管，所述导管具有取样部分（6），所述取样部分（6）布置成沿着所述血管的长度在多个位置处捕获血液样本，以及设备，用于分析从多个位置沿取得的血液 血管的长度并提供沿着血管长度的浓度水平。