公开(公告)号：WO99015905A1

公开(公告)日：1999-04-01

申请号：PCT/EP1998/005994

申请日：1998-09-22

IPC: G01N35/00 ,  G01N35/02 ,  G01N35/04 ,  B25J7/00 ,  B25J15/00

CPC classification number: G01N35/0099 ,  G01N35/028 ,  G01N2035/042 ,  G01N2035/0425 ,  Y10T436/11 ,  Y10T436/113332 ,  Y10T436/114998

Abstract: The invention provides exemplary systems, devices and methods for manipulating and handling multi-well plates. In one exemplary embodiment, a system is provided which comprises a robot having a base member and at least one arm. The arm includes a grasping mechanism which is adapted to grasp the plate. Further, the grasping mechanism is configured to receive the plate in a repeatable and known location such that the location of each well relative to the grasping mechanism is known by the robot.

Abstract translation: 本发明提供了用于操纵和处理多孔板的示例性系统，装置和方法。 在一个示例性实施例中，提供了一种系统，其包括具有基座构件和至少一个臂的机器人。 臂包括适于抓住板的抓握机构。 此外，把持机构构造成在可重复且已知的位置处容纳板，使得每个井相对于把持机构的位置由机器人已知。

公开(公告)号：WO1997011352A1

公开(公告)日：1997-03-27

申请号：PCT/FI1996000499

申请日：1996-09-20

Applicant: LABSYSTEMS OY ,  PRIHA, Matti ,  TUPAKKA, Heikki

Inventor： LABSYSTEMS OY

IPC: G01N21/01

CPC classification number: B01L9/523 ,  B01L2300/0829 ,  G01N35/028 ,  G01N2035/042 ,  Y10T436/11 ,  Y10T436/113332 ,  Y10T436/114998

Abstract: The invention relates to a holder in which sample-holding plates can be handled. It has a retainer (49) for pressing a plate placed in the holder both against the back wall and against a side wall. Thus a plate of a certain type will always settle in the same position in the holder. It is also possible to use in the holder plates of many sizes, which can be kept in place during handling owing to the retainer. The invention is suitable for use in particular in assay methods in which samples to be assayed are handled on plates comprising a plurality of wells, for example in optical analysers or other apparatuses.

Abstract translation: 本发明涉及可以处理样品保持板的保持器。 其具有用于将放置在保持器中的板压靠在后壁上并抵靠侧壁的保持器（49）。 因此，某种类型的板材将始终处于保持器中相同的位置。 也可以在许多尺寸的保持板中使用，其可以由于保持器而在处理期间保持在适当位置。 本发明特别适用于测定方法，其中待测定的样品在包括多个孔的板上处理，例如在光学分析仪或其他装置中。

公开(公告)号：WO1992022800A1

公开(公告)日：1992-12-23

申请号：PCT/US1992005015

申请日：1992-06-12

Applicant: ABBOTT LABORATORIES ,  WHITE, David, A. ,  WROBLEWSKI, Mieczyslaw ,  KOTLARIK, John, J.

Inventor： ABBOTT LABORATORIES

IPC: G01N21/01

CPC classification number: G01N35/109 ,  B01L3/0262 ,  B01L3/5085 ,  G01N15/1468 ,  G01N21/82 ,  G01N35/0095 ,  G01N35/0098 ,  G01N35/028 ,  G01N35/1004 ,  G01N2035/042 ,  G01N2035/0425 ,  G01N2035/0491 ,  G01N2035/1018 ,  G01N2035/1025 ,  G01N2035/1034 ,  G01N2201/0446 ,  G01N2201/0461 ,  G01N2201/0492 ,  G02B7/28 ,  Y10T137/7306 ,  Y10T436/115831

Abstract: A liquid dispensing mechanism (34) is provided which includes a dispensing probe having a tip (70) for dispensing liquid, a pump for collectively discharging fluid from the probe tip (70) in measured quantities such as droplets. The dispensing probe has the capability to detect droplet formation and droplet separation from the probe (70) through use of a radio-frequency signal (74, 76) to the probe tip (70) and a conductive element (72) connected to amplifying and analyzing circuitry (78, 80, 82, 84) disposed below the dispensing probe (70) and a reaction well (16) which contains a receiving fluid. The conductive element (72) also detects when the probe has been inserted into the receiving fluid.

Abstract translation: 提供了液体分配机构（34），其包括具有用于分配液体的尖端（70）的分配探针，用于以诸如液滴的测量量从探针尖端（70）共同排放流体的泵。 分配探针具有通过使用射频信号（74,76）到探针尖端（70）和导电元件（72）来检测来自探针（70）的液滴形成和液滴分离的能力，导电元件（72）连接到放大和 设置在分配探针（70）下方的分析电路（78,80,82,84）和包含接收流体的反应井（16）。 导电元件（72）还检测探针何时插入接收流体。

公开(公告)号：WO1991017460A1

公开(公告)日：1991-11-14

申请号：PCT/FI1990000124

申请日：1990-05-08

Applicant: WALLAC OY ,  SONNE, Vesa ,  LEHTINEN, Kauko ,  YRJÖNEN, Tapio

Inventor： WALLAC OY

IPC: G01T01/204

CPC classification number: G01T7/02 ,  G01N2035/042 ,  G01N2035/0425 ,  G01T1/2045

Abstract: The present invention shows a new apparatus in the field of liquid scintillation counting. The conventional liquid scintillation counters have been designed to measure samples in vials, which volume is typically 6 or 20 milliliters. In addition a special purpose liquid scintillation counter, the Betaplate is adapted to measure 6 samples at a time deposited on a multi-well sample plate with fixed format and sample well volume. For avoiding the limitations of the above-mentioned liquid scintillation counters, when samples are deposited on various type multi-well sample plates, a new apparatus is shown which is adapted to measure simultaneously one or several liquid scintillation or corresponding samples deposited in sample plates (10, 20) with various sample well volumes belonging to a preselected assortment of different multi-well sample plate types, each having a characteristic two dimensional array of sample wells.

Abstract translation: 本发明示出了液体闪烁计数领域中的新设备。 传统的液体闪烁计数器被设计用于测量小瓶中的样品，其体积通常为6或20毫升。 另外，特殊目的的液体闪烁计数器，Betaplate适用于一次沉积在具有固定格式和样品井体积的多孔样品板上的6个样品。 为了避免上述液体闪烁计数器的限制，当样品沉积在各种类型的多孔样品板上时，示出了一种新的装置，其适于同时测量沉积在样品板中的一种或多种液体闪烁体或相应的样品（ 10,20），其具有属于预选的不同多孔样品板类型的各种样品孔体积，每种具有样品孔的特征二维阵列。