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    IN VITRO ASSAY METHODS FOR CLASSIFYING EMBRYOTOXICITY OF COMPOUNDS
    92.
    发明申请
    IN VITRO ASSAY METHODS FOR CLASSIFYING EMBRYOTOXICITY OF COMPOUNDS 审中-公开
    用于分类化合物的胚胎毒性的体外测定方法

    公开(公告)号：WO2008107912A3

    公开(公告)日：2008-11-27

    申请号：PCT/IN2008000126

    申请日：2008-03-05

    申请人： RELIANCE LIFE SCIENCES PVT LTD ,  KHANNA APAMA

    发明人： KHANNA APAMA ,  MEHTA ASHISH ,  REDDY VIJAY BHASKAR

    IPC分类号： G01N33/50

    CPC分类号： C11B1/04 ,  C11B1/10 ,  C11B3/12 ,  C11B13/00 ,  C11C3/08 ,  G01N33/5014 ,  Y02W30/74

    摘要： The present disclosure provides methods useful for screening compounds and/or compositions, for example potential drug candidates. The results of the screening assays correlate to the effects of the compounds on the molecular and/or cellular level of the human body. Also disclosed are screening assays utilizing human embryonic stem cells RELICELL®hES of Indian origin. The methods disclosed herein correlate well with animal preclinical toxicity studies done in a clinical trial setup.

    摘要翻译： 本公开提供了用于筛选化合物和/或组合物例如潜在候选药物的方法。 筛选测定的结果与化合物对人体分子和/或细胞水平的影响相关。 还公开了利用印度来源的人胚胎干细胞RELESELL®hES的筛选测定。 本文公开的方法与在临床试验设置中进行的动物临床前毒性研究很好地相关。

    ADDITIVES FOR INCREASING THE SEPARATION YIELD OF TALL OIL SOAP FROM BLACK LIQUORS
    93.
    发明申请
    ADDITIVES FOR INCREASING THE SEPARATION YIELD OF TALL OIL SOAP FROM BLACK LIQUORS 审中-公开
    用于提高黑液中高油脂皂分离产量的添加剂

    公开(公告)号：WO2008092005A3

    公开(公告)日：2008-10-23

    申请号：PCT/US2008051915

    申请日：2008-01-24

    申请人： NALCO CO ,  SVARZ JAMES J ,  DUGGIRALA PRASAD Y ,  WORLEY GRADY E

    发明人： SVARZ JAMES J ,  DUGGIRALA PRASAD Y ,  WORLEY GRADY E

    IPC分类号： C11B13/00

    CPC分类号： C11B13/02 ,  C11C1/08 ,  Y02W30/74

    摘要： Methods of increasing the yield of tall oil soap from a black liquor are provided. In an embodiment, the method comprises adding a separation aid to the black liquor. The separation aid comprises alkyl alcohol alkoxylates of formula RO[(CH 2 CHCH 3 O)x(CH 2 CH 2 O)y]M and combinations thereof, wherein R is straight or branched alkyl of about 8 to about 22 carbon atoms; x is 1 to about 20; y is about 20 to about 80 and M is H or an alkali metal.

    摘要翻译： 提供了从黑液中提高妥尔油皂产量的方法。 在一个实施方案中，该方法包括向黑液添加分离助剂。 分离助剂包含式RO [（CH 2 SUBCH 3 CH 2）x CH 2 CH 2 CH 2 CH 2 CH 2 CH 2 CH 2 CH 2 CH 2 CH 2 CH 2 CH 2 O）y] M及其组合，其中R是约8至约22个碳原子的直链或支链烷基; x是1至约20; y为约20至约80，M为H或碱金属。

    PROCESS FOR ISOLATION OF FATTY ACIDS, RESIN ACIDS AND STEROLS FROM TALL OIL PITCH
    96.
    发明申请
    PROCESS FOR ISOLATION OF FATTY ACIDS, RESIN ACIDS AND STEROLS FROM TALL OIL PITCH 审中-公开
    从石油沥青中分离脂肪酸，树脂酸和五味子的方法

    公开(公告)号：WO2008099051A2

    公开(公告)日：2008-08-21

    申请号：PCT/FI2008000027

    申请日：2008-02-15

    申请人： RAVINTORAISIO OY ,  HAMUNEN ANTTI

    发明人： HAMUNEN ANTTI

    IPC分类号： C11B13/00

    CPC分类号： C11B13/005 ,  Y02W30/74

    摘要： The invention relates to a process for recovering fatty acids, resin acids and sterols from tall oil pitch, said process comprising a) saponifying the tall oil pitch with an alkali to hydrolyse esters included in the pitch to free alcohols and organic acids in salt form, b) acidulating the saponified pitch with a mineral acid to convert the organic acids in salt form into free organic acids and to form an organic phase and an aqueous phase, c) separating the aqueous phase from the organic phase, d) evaporation fractionating the organic phase to obtain a distillate rich in sterols, fatty acids and resin acids, e) evaporation fractionating the distillate to obtain a bottom fraction rich in sterols, and a distillate rich in fatty acids and resin acids, and f) subjecting the sterols in the sterol-rich bottom fraction to crystallisation purification. The invention also relates to an alternative process including steps a) to c) followed by d1) treating the organic phase with an alkali to destroy excess mineral acid used for acidulating the saponified pitch, e1) evaporation fractionating the alkali-treated organic phase to obtain a distillate rich in fatty acids and resin acids and a bottom fraction rich in sterols, f1) evaporation fractionating the bottom fraction to obtain a distillate rich in sterols, and g1) subjecting the sterols in the sterol-rich distillate to crystallisation purification.

    摘要翻译： 本发明涉及从妥尔油沥青中回收脂肪酸，树脂酸和固醇的方法，所述方法包括：a）用碱皂化妥尔油沥青以水解包含在沥青中的酯，以游离醇和有机酸的盐形式， b）用无机酸酸化皂化沥青，将盐形式的有机酸转化成游离的有机酸，并形成有机相和水相，c）将水相与有机相分离，d）将有机相蒸发分馏 获得富含固醇，脂肪酸和树脂酸的馏出物，e）蒸馏分馏馏出物以获得富含固醇的底馏分，富含脂肪酸和树脂酸的馏出物，以及f）使固醇中的甾醇 丰富的底部馏分进行结晶纯化。 本发明还涉及一种替代方法，其包括步骤a）至c），然后是d1）用碱处理有机相以破坏用于酸化皂化沥青的过量无机酸，e1）蒸发分级碱处理的有机相以获得 富含脂肪酸和树脂酸的馏出物和富含固醇的底部馏分，f1）蒸馏分馏底部馏分以获得富含固醇的馏出物，和g1）使富含固醇的馏出物中的甾醇经过结晶纯化。

    METHOD OF WAX REMOVAL FROM VEGETABLE OILS
    98.
    发明申请
    METHOD OF WAX REMOVAL FROM VEGETABLE OILS 审中-公开
    从植物油中去除卵的方法

    公开(公告)号：WO2006004454A8

    公开(公告)日：2007-03-22

    申请号：PCT/RU2005000281

    申请日：2005-05-23

    申请人： TOKAREV VLADIMIR DMITRIEVICH ,  TOKAREV PAVEL VLADIMIROVICH

    发明人： TOKAREV VLADIMIR DMITRIEVICH ,  TOKAREV PAVEL VLADIMIROVICH

    IPC分类号： C11B3/00 ,  C11B3/10 ,  C11B3/16 ,  C11B7/00 ,  C11B11/00

    CPC分类号： C11B11/00 ,  C11B3/10 ,  C11B3/16 ,  C11B7/0075 ,  Y02W30/74

    摘要： The invention relates to the field of vegetable oil refining technologies, more particularly, to the technology of wax removal from vegetable oils by freezing out or winterization, and can be used for the improvement of the existing and the development of new technologies. Separated used filtering product regeneration step is added to the method of wax removal from vegetable oils the working cycle of which comprises winterization of the vegetable oil with the addition of auxiliary filtering powders, low temperature exposure of the oil and separation of the used filtering powder with the wax containing residue from the refined vegetable oil. To this end the used filtering powder is mixed with the additionally introduced fatty product to a paste condition, said paste is heated with stirring to the melting point of all the waxed and the resultant mixture is separated by centrifugation to obtain regenerated dry filtering powder and a wax containing fatty product. The regenerated filtering powder can be multiply recycled as the auxiliary filtering powder in the subsequent working cycles comprising winterization of the new vegetable oil portions wherein each working cycle is followed by regeneration of the used filtering powder.

    摘要翻译： 本发明涉及植物油精炼技术领域，特别涉及通过冷冻或冬季化从植物油中除蜡的技术，可用于改进现有技术和新技术的开发。 将分离的过滤产物再生步骤添加到从植物油中除蜡的方法中，其工作循环包括加入辅助过滤粉末使植物油冷却，低温暴露于油中并将所用过滤粉末与 该蜡含有来自精制植物油的残留物。 为此，将所使用的过滤粉末与附加引入的脂肪产物混合至糊状，将所述糊料在搅拌下加热至所有打蜡的熔点，并通过离心分离得到的再生干燥过滤粉末和 含蜡的脂肪产品。 再生的过滤粉末可以在随后的工作循环中作为辅助过滤粉末进行多次再循环，包括使新的植物油部分变冷，其中每个工作循环随后再生所用的过滤粉末。