公开(公告)号：WO2004006767A2

公开(公告)日：2004-01-22

申请号：PCT/US0321901

申请日：2003-07-15

Applicant: SPIRATION INC ,  SIROKMAN WILLIAM A ,  DEVORE LAURI J ,  KUTSKO JAMES M ,  DILLARD DAVID H ,  WESTMAN PETER R

Inventor： SIROKMAN WILLIAM A ,  DEVORE LAURI J ,  KUTSKO JAMES M ,  DILLARD DAVID H ,  WESTMAN PETER R

IPC: A61B5/107

CPC classification number: A61B5/1076

Abstract: AbstractThe invention provides a device for measuring an inside diameter of a body lumen, such as an air passageway. The device includes a flexible catheter (110, 310) having an inflation lumen (112, 312), a fluid dispenser (102, 200) in fluid communication with the inflation lumen and operable to communicate a measurable fluid volume change with the inflation lumen (112, 312), and an expandable member (120) in fluid communication with the inflation lumen and having a known relationship between volume and a changeable transverse dimension, the transverse dimension being changeable in response to fluid volume changes of the fluid dispenser and arranged for placement adjacent to opposing portions of an interior wall of the air passageway (80). The expandable member (120) may be dimensioned for transoral placement into the air passageway (80, and may comprise a balloon that includes a complaint material or a non-compliant material.

Abstract translation: 摘要本发明提供了一种用于测量诸如空气通道的体腔内径的装置。 该装置包括具有充气腔（112,312）的柔性导管（110,310），与充气腔流体连通的流体分配器（102,200），可操作以将可测量的流体体积变化与充气腔 112和312），以及与所述充气腔流体连通并具有体积和可变横向尺寸之间的已知关系的可膨胀构件（120），所述横向尺寸可响应于所述流体分配器的流体体积变化而变化， 邻近空气通道（80）的内壁的相对部分的放置。 可膨胀构件（120）的尺寸可以用于横向放置到空气通道（80）中，并且可以包括包括投诉材料或不符合材料的气囊。

公开(公告)号：WO2003096886A3

公开(公告)日：2003-11-27

申请号：PCT/US2003/005921

申请日：2003-02-26

Applicant: SPIRATION, INC. ,  BARRY, Robert, Lawrence ,  DEVORE, Lauri, J.

Inventor： BARRY, Robert, Lawrence ,  DEVORE, Lauri, J.

IPC: A61B18/18

Abstract: An electrosurgery device according to an embodiment of the invention captures a lymph nodule and resects it. The lymph node is captured with a vacuum and resected it with an electrode, which minimizes bleeding and limits the potentially malignant node from coming into contact with surround tissue as it is resected and removed. This limits the potential for inadvertent cancer spread. An electrosurgery device according to an embodiment of the invention also allows several lymph nodes to be resected in a single procedure, each lymph node being easily indexed according to its nodal station and stored in a manner that limits the potential for cross-contamination. An electrosurgery device according to an embodiment of the invention further provides a collector for individually receiving resected lymph nodes. The collector may be easily detached and sent to pathology without interrupting resection of other lymph nodes.

公开(公告)号：WO2003088912A3

公开(公告)日：2003-10-30

申请号：PCT/US2003/011974

申请日：2003-04-16

Applicant: SPIRATION, INC. ,  DEVORE, Lauri, J.

Inventor： DEVORE, Lauri, J.

IPC: A61B17/04

Abstract: An intra-bronchial device may be placed in an air passageway of a patient to collapse a lung portion associated with the air passageway. The device includes an obstructing member (40) that prevents air from being inhaled into the lung portion to collapse the lung portion, and an anchoring device (100) that anchors the obstructing member in the air passageway by engaging the obstructing member (90) and the air passageway wall. The anchoring device (100) may frictionally engage the obstructing member and the air passageway, or engage both by piercing. The engagement provided by the anchoring device may be releasable for removal of the obstructing member (90). The anchoring device (100) may be balloon expandable from a first shape to a second shape that engages the obstructing member (90) and the air passageway. The obstructing member (90) may be a one-way valve.

公开(公告)号：WO2003032864A2

公开(公告)日：2003-04-24

申请号：PCT/US2002/032886

申请日：2002-10-15

Applicant: SPIRATION, INC. ,  CORCORAN, Dean, T.

Inventor： CORCORAN, Dean, T.

IPC: A61F

CPC classification number: A61F2/04 ,  A61B17/122 ,  A61F2002/043

Abstract: A constriction device that constricts body tissue and is formed of relatively thin elastic material includes a tear resistance structure to preclude an inadvertent tear in the device from propagating through the device. The tear resistance structure includes a plurality of intersecting ribs formed in the elastic material. The ribs circumscribe the device and define rectangular, square, diamond, wavy, or knurled patterns.

Abstract translation: 收缩身体组织并由相对薄的弹性材料形成的收缩装置包括防撕裂结构，以防止装置中的无意撕裂传播通过装置。 抗撕裂结构包括形成在弹性材料中的多个相交肋。 肋骨围绕设备并定义矩形，正方形，菱形，波浪形或滚花图案。

公开(公告)号：WO2018136039A1

公开(公告)日：2018-07-26

申请号：PCT/US2017/013812

申请日：2017-01-17

Applicant: SPIRATION, INC. D/B/A OLYMPUS RESPIRATORY AMERICA

Inventor： SHUMAN, Brandon

IPC: A61B1/267 ,  A61B18/12 ,  A61B18/14

Abstract: Disclosed embodiments include an apparatus, a system and a method for shunting current between first and second electrodes to temporarily reduce current applied through first and second electrodes. In a nonlimiting embodiment, an illustrative apparatus includes first and second electrode couplings configured to electrically engage proximal ends of the first and second electrodes, respectively, the first and second electrodes each having a distal end configured to conduct electrical current generated by a switchable current source therebetween and through an electrically conductive target. A current inrush regulator is configured to temporarily shunt at least a portion of the electrical current generated by the switchable current source to temporarily reduce the electrical current passing between the distal ends of the first and second electrodes through the electrically conductive target.

公开(公告)号：WO2017165310A1

公开(公告)日：2017-09-28

申请号：PCT/US2017/023242

申请日：2017-03-20

Applicant: SPIRATION, INC. D/B/A OLYMPUS RESPIRATORY AMERICA

Inventor： SHUMAN, Brandon J. ,  DILLARD, David H. ,  LAMBE, Peter A. ,  DALE, Nathan ,  SALEIRA, Christopher A. ,  ZHANG, Fan ,  HOSTEIN, Nicolas G. ,  MILLS, Randall D. ,  JUREVICIUS, Christine N. ,  SMITH, Michael S.

IPC: A61B18/14 ,  A61B18/00

CPC classification number: A61B18/1492 ,  A61B2018/00196 ,  A61B2018/00541 ,  A61B2018/00577 ,  A61B2018/00589 ,  A61B2018/1427 ,  A61B2018/1435 ,  A61B2018/144 ,  A61B2018/1475 ,  A61B2218/002

Abstract: Disclosed embodiments include apparatuses, systems, and methods for positioning electrodes within a body. In an illustrative embodiment, an apparatus for slidably moving multiple features relative to a sheath inserted into a body and positioned relative to a reference point includes a primary actuator configured to move a primary electrode, a secondary actuator configured to move a secondary electrode, and a control mechanism. The control mechanism is configured to selectively prevent movement of at least one of the primary actuator based on a position of the secondary actuator and of the secondary actuator based on a position of the primary actuator and lock positions of the primary actuator and the secondary actuator.

Abstract translation: 所公开的实施例包括用于将电极定位在体内的装置，系统和方法。 在说明性实施例中，用于相对于插入到主体中并且相对于参考点定位的护套可滑动地移动多个特征的设备包括：被配置为移动主电极的主致动器，被配置为移动副电极的副致动器，以及 控制机制。 所述控制机构被配置为基于所述主致动器的位置和所述主致动器和所述次致动器的锁定位置基于所述次致动器和所述次致动器的位置选择性地防止所述主致动器中的至少一个的移动。

公开(公告)号：WO2016154170A1

公开(公告)日：2016-09-29

申请号：PCT/US2016/023516

申请日：2016-03-22

Applicant: SPIRATION, INC., D/B/A OLYMPUS RESPIRATORY AMERICA

Inventor： SHUMAN, Brandon, J. ,  DILLARD, David, H.

IPC: A61B10/02 ,  A61B10/04

CPC classification number: A61B10/04 ,  A61B1/018 ,  A61B1/2676 ,  A61B10/0266 ,  A61B17/3478 ,  A61B2010/045 ,  A61B2017/0034 ,  A61B2017/00867

Abstract: An apparatus, comprising: a biopsy needle having a distal end and a proximal end, all or a portion of the biopsy needle being movable between a collapsed state and an expanded state; a sheath having a distal end and a proximal end, wherein the biopsy needle in the collapsed state is contained within the sheath, and in the expanded state at least the distal end of the biopsy needle extends from the distal end of the sheath; wherein the biopsy needle is provided with two or more sleeves, which at least partially overlap in the collapsed configuration and which cylindrically expand to provide an increased radius, relative to a radius in the collapsed state, for sampling in the expanded configuration, and wherein a cross section of the distal end of the biopsy needle in the expanded state is a substantially circular cross section.

Abstract translation: 一种装置，包括：具有远端和近端的活检针，活检针的全部或一部分可在折叠状态和展开状态之间移动; 护套，其具有远端和近端，其中处于折叠状态的活检针被包含在护套内，并且在膨胀状态下，活检针的至少远端从护套的远端延伸; 其中所述活检针具有两个或更多个套筒，所述两个或多个套筒在所述塌缩构型中至少部分重叠，并且相对于所述塌缩状态的半径提供圆柱形膨胀以提供增加的半径，用于在所述膨胀构型中进行采样，并且其中 处于膨胀状态的活检针的远端的横截面是大致圆形的横截面。

公开(公告)号：WO2015153493A1

公开(公告)日：2015-10-08

申请号：PCT/US2015/023400

申请日：2015-03-30

Applicant: SPIRATION, INC.

Inventor： GONZALEZ, Hugo, Xavier

IPC: A61B1/00 ,  A61B1/012 ,  A61B1/267 ,  A61B10/00 ,  A61B10/04 ,  A61B19/00

CPC classification number: A61B5/1076 ,  A61B1/00 ,  A61B1/012 ,  A61B1/04 ,  A61B1/267 ,  A61B1/2676 ,  A61B5/08 ,  A61B5/1079 ,  A61B90/06 ,  A61B2090/061 ,  A61F2220/0016

Abstract: An airway measurement/estimation device may comprise a sizing shaft at least partially disposable with a bronchoscope, 'The sizing shaft may comprise a plurality of bristles of known lengths such that when the sizing shaft is inserted into a patient's airway, and viewed through a bronchoscope, the size or diameter of the airway may be approximated based at least in part on the size of the bristles in relation to the size of the airway.

Abstract translation: 气道测量/估计装置可以包括至少部分地与支气管镜一次性的定径轴。定径轴可以包括多个已知长度的刷毛，使得当定径轴插入到患者的气道中并且通过支气管镜观察时 至少部分地基于刷毛的尺寸相对于气道的尺寸来近似估计气道的尺寸或直径。

公开(公告)号：WO2013148217A1

公开(公告)日：2013-10-03

申请号：PCT/US2013/031067

申请日：2013-03-13

Applicant: SPIRATION, INC.

Inventor： DILLARD, David, H. ,  GONZALEZ, Hugo, X. ,  HOFFMAN, Peter ,  SHUMAN, Brandon, James

IPC: A61B5/05 ,  A61B5/055

CPC classification number: A61B19/54 ,  A61B5/05 ,  A61B5/055 ,  A61B5/062 ,  A61B17/3468 ,  A61B18/04 ,  A61B18/1492 ,  A61B90/39 ,  A61B2018/00047 ,  A61B2018/00541 ,  A61B2018/00577 ,  A61B2090/3908 ,  A61B2090/392 ,  A61B2090/3954 ,  A61B2090/3966 ,  A61B2090/3995 ,  A61B2562/17 ,  A61N7/022

Abstract: Embodiments of the present invention include devices, systems, and methods for implanting and locating traceable markers in a region of a patient's body such as a lung, and in particular lung nodules which may be difficult to locate using traditional means. Further embodiments describe devices, systems, and methods that may be used to treat regions in the lung such as lung nodules with various treatment modalities including heating, microwave irradiation, chemical treatment, and which may be used in conjunction with embodiments of the traceable markers described herein.

Abstract translation: 本发明的实施例包括用于在患者身体（例如肺）的区域中植入和定位可跟踪标记的装置，系统和方法，特别是可能难以使用传统手段定位的肺结节。 另外的实施方案描述了可用于治疗肺中的区域的装置，系统和方法，例如具有各种治疗方式的肺结节，包括加热，微波照射，化学治疗，并且可以与所描述的可追踪标记的实施方案结合使用 于此。

公开(公告)号：WO2013130484A1

公开(公告)日：2013-09-06

申请号：PCT/US2013/027828

申请日：2013-02-26

Applicant: SPIRATION, INC.

Inventor： DILLARD, David, H. ,  GONZALEZ, Xavier ,  HOFFMAN, Peter ,  O'CONNELL, Desmond ,  THRALLS, Christopher

IPC: A61F11/00

CPC classification number: A61M25/04 ,  A61B1/01 ,  A61B10/02 ,  A61B10/0233 ,  A61B17/3421 ,  A61B17/3478 ,  A61B90/39 ,  A61B2017/00809 ,  A61B2017/22039 ,  A61B2017/22047 ,  A61B2017/22069 ,  A61B2017/22077 ,  A61B2017/3425 ,  A61B2090/3966 ,  A61M25/0108 ,  A61M25/09 ,  A61M2025/0177

Abstract: In certain embodiments, a device is configured to be delivered to the site of a nodule in the lung or other body organ or lumen. The device can be configured to attach directly to the target nodule or to tissue adjacent the target nodule. The device can be configured t provide repeatable access to the site of the target nodule. In some embodiments, the device includes a guide wire that can extend proximal the device. In some embodiments, the device can include a channel portion through which medical devices and/or instruments can be navigated. In some embodiments, the device can be deployed in the wall of an airway or other body lumen to provide trans luminal access to a nodule outside of the lumen.

Abstract translation: 在某些实施例中，装置被配置为被递送到肺或其他身体器官或内腔中的结节部位。 该装置可以被配置为直接附着到目标结节或邻近目标结节的组织。 该设备可以配置为提供可重复访问目标结节的位置。 在一些实施例中，该装置包括能够在该装置附近延伸的导丝。 在一些实施例中，该装置可以包括通道部分，通过该通道部分可以导航医疗装置和/或器械。 在一些实施例中，该装置可以部署在气道或其他体腔的壁中，以提供对管腔外的结节的经腔内通路。