公开(公告)号：WO2007044357A2

公开(公告)日：2007-04-19

申请号：PCT/US2006/038692

申请日：2006-10-03

Applicant: PERICOR THERAPEUTICS, INC. ,  STOVER, Richard, R. ,  DIXON, Ross ,  MANGANO, Dennis, T. ,  WU, Sharon ,  SACK, Marvin, J.

Inventor： STOVER, Richard, R. ,  DIXON, Ross ,  MANGANO, Dennis, T. ,  WU, Sharon ,  SACK, Marvin, J.

IPC: A61K31/7056

CPC classification number: A61K47/18 ,  A61K9/0019 ,  A61K9/19 ,  A61K31/7056 ,  A61K47/02 ,  A61K47/183

Abstract: This invention relates to kits, compositions, and formulations comprising AICA riboside and analogs thereof and methods of using the same. The kits may comprise the compositions and/or formulations within a pH range, in a sterilized form. The kits may further comprise containers with a second therapeutic agent. The kits and compositions herein can be used to prevent morbidity/mortality in a patient or to prevent/treat an ischemic condition, a condition regulated by adenosine, or a condition associated with reduced blood flow to a tissue in a patient.

Abstract translation: 本发明涉及包含AICA riboside及其类似物的试剂盒，组合物和制剂及其使用方法。 试剂盒可以以无菌形式包含pH范围内的组合物和/或制剂。 试剂盒还可以包含具有第二治疗剂的容器。 本发明的试剂盒和组合物可用于预防患者的发病率/死亡率或预防/治疗缺血性疾病，由腺苷调节的病症，或与患者血液中血液流量减少有关的病症。

公开(公告)号：WO2008086341A1

公开(公告)日：2008-07-17

申请号：PCT/US2008/050491

申请日：2008-01-08

Applicant: PERICOR THERAPEUTICS, INC. ,  STOVER, Richard, R.

Inventor： STOVER, Richard, R.

IPC: A61K31/4178 ,  A61K9/70

CPC classification number: A61K31/4178 ,  A61K9/7023 ,  C07D405/04 ,  C07H19/052

Abstract: The present invention provides transdermal administration of AICA riboside, or a prodrugs, analogs, or salts thereof, and/or a blood clotting inhibitor for preventing or reducing adverse side effects in a patient. The type of patient that may benefit includes a patient with decreased left ventricular function, a patient with a prior myocardial infarction, a patient undergoing non-vascular surgery, or a fetus during labor and delivery.

Abstract translation: 本发明提供透皮给药AICA核糖苷或其前体药物，类似物或其盐，和/或用于预防或减少患者不利副作用的凝血抑制剂。 可能受益的患者的类型包括左心室功能下降的患者，先前的心肌梗塞的患者，经历非血管手术的患者，或在分娩期间的胎儿。

公开(公告)号：WO2013022945A3

公开(公告)日：2013-02-14

申请号：PCT/US2012/049960

申请日：2012-08-08

Applicant: OASYS WATER, INC. ,  MCGINNIS, Robert ,  MANDELL, Aaron ,  STOVER, Richard

Inventor： MCGINNIS, Robert ,  MANDELL, Aaron ,  STOVER, Richard

IPC: B01D63/08 ,  B01D63/10 ,  B01D65/00 ,  B01D61/36

Abstract: The invention relates to membrane modules and applications therefor. In particular, the invention relates to the construction of membrane modules for use in forward osmosis, heat exchange, and distillation processes.

公开(公告)号：WO2011079045A2

公开(公告)日：2011-06-30

申请号：PCT/US2010/061056

申请日：2010-12-17

Applicant: ENERGY RECOVERY, INC. ,  PINTO, Juan Miguel ,  MARTIN, Jeremy G. ,  STOVER, Richard L.

Inventor： PINTO, Juan Miguel ,  MARTIN, Jeremy G. ,  STOVER, Richard L.

IPC: F28F5/00 ,  F04F99/00

CPC classification number: F04F13/00 ,  F04F1/00 ,  F04F99/00

Abstract: A rotary energy recovery device (11) wherein a multi-channel cylindrical rotor (15) revolves with its end faces (32) juxtaposed in sealing relationship with end surfaces (33) of a pair of flanking end covers (19, 21), and wherein inlet and outlet fluid passageways (27, 29) are provided in each end cover. Fluid may be directed into the rotor channels (16) and allowed to exit therefrom in an axial direction parallel to the axis of the rotor; however, rotor revolution is self-driven as a result of the interior design of the channels (16) which extend axially through the rotor and are shaped so that fluid flow therethrough creates a torque.

Abstract translation: 一种旋转能量回收装置（11），其中多通道圆柱形转子（15）以其端面（32）与一对侧面端部（32）的端面（33）以密封关系并置的方式旋转， 盖（19,21），并且其中入口和出口流体通路（27,29）设置在每个端盖中。 流体可以被引导到转子通道（16）中并且允许流体沿着平行于转子的轴线的轴向方向从其排出; 然而，由于通道（16）的内部设计导致转子旋转自行驱动，所述通道（16）轴向延伸穿过转子并且被成形为使流过其的流体产生扭矩。

公开(公告)号：WO2009046429A3

公开(公告)日：2009-05-28

申请号：PCT/US2008078961

申请日：2008-10-06

Applicant: ENERGY RECOVERY INC ,  PIQUE GONZALO G ,  STOVER RICHARD L ,  MARTIN JEREMY G ,  PINTO JUAN MIGUEL

Inventor： PIQUE GONZALO G ,  STOVER RICHARD L ,  MARTIN JEREMY G ,  PINTO JUAN MIGUEL

IPC: F01D15/08 ,  F04B35/00 ,  F04F99/00

CPC classification number: B01D61/06 ,  B01D61/10 ,  B01D2313/246 ,  C02F1/441 ,  C02F2103/08 ,  C02F2303/10 ,  Y02A20/131

Abstract: A rotary pressure transfer device utilizes a multi-channel, generally cylindrical rotor (15) that revolves with its flat end faces juxtaposed with flat end surfaces of a pair of flanking end covers (19, 21) in which inlet and outlet passageways are provided. The design is such that there are only oblique ramps (65) in the passageways on the high pressure side which create directional flow of liquid to cause rotor revolution in the desired direction. Passageways (27a, 27b) on the low pressure side may be shaped so that there is essentially longitudinal flow entry and discharge of liquid between the channels and the passageways, or passageways (71) may be constructed to create directional flow that slightly retards rotor revolution in such desired direction.

Abstract translation: 旋转压力传送装置利用多通道，大体圆柱形的转子（15），其旋转，其扁平端面与设置有入口和出口通道的一对侧面端盖（19,21）的平坦端表面并置。 该设计使得在高压侧的通道中仅存在斜坡（65），其产生液体的方向性流动，以使转子沿所需方向旋转。 在低压侧的通道（27a，27b）可以被成形为使得在通道和通道之间基本上纵向地进入和排出液体，或者可以构造通道（71）以产生稍微延迟转子旋转的方向流 在所希望的方向。

公开(公告)号：WO2008042693A1

公开(公告)日：2008-04-10

申请号：PCT/US2007/079674

申请日：2007-09-27

Applicant: ENERGY RECOVERY, INC. ,  MARTIN, Jeremy, G. ,  STOVER, Richard, L.

Inventor： MARTIN, Jeremy, G. ,  STOVER, Richard, L.

IPC: F04F11/02

CPC classification number: F04F13/00 ,  B01D61/06 ,  B01D61/10 ,  B01D2313/246 ,  C02F1/441 ,  C02F2103/08 ,  C02F2303/10

Abstract: A pressure transfer device for the transfer of pressure energy from a high pressure fluid stream to a lower pressure fluid stream wherein a generally cylindrical housing (61) contains a rotor (63) having a plurality of channels (65) extending axially therethrough that revolves about a central stator (67) or within a surrounding sleeve (73) and a pair of end covers (69, 71) which slidingly and sealingly interface with respective planar end faces (68) of the rotor. The end covers (69, 71) and the accompanying components of the device are constructed so as to allow the channels to be at least twice filled with a high pressure first liquid during each revolution of the rotor and thus discharge twice the volume of a pressurized second liquid than if they were filled only one with high pressure liquid.

Abstract translation: 一种用于将压力能量从高压流体流转移到低压流体流的压力传递装置，其中大致圆柱形的壳体（61）包含转子（63），转子（63）具有轴向延伸穿过其中的多个通道（65），其围绕 中心定子（67）或围绕套筒（73）内的一对端盖（69,71），其与转子的各个平面端面（68）滑动并密封地接合。 端盖（69,71）和装置的相关部件被构造成允许通道在转子的每转期间被高压第一液体填充至少两次，并且因此将两倍体积的加压 第二种液体比用高压液体填充一种液体。

公开(公告)号：WO2007044357A3

公开(公告)日：2007-09-27

申请号：PCT/US2006038692

申请日：2006-10-03

Applicant: PERICOR THERAPEUTICS INC ,  STOVER RICHARD R ,  DIXON ROSS ,  MANGANO DENNIS T ,  WU SHARON ,  SACK MARVIN J

Inventor： STOVER RICHARD R ,  DIXON ROSS ,  MANGANO DENNIS T ,  WU SHARON ,  SACK MARVIN J

IPC: A61K31/00

CPC classification number: A61K47/18 ,  A61K9/0019 ,  A61K9/19 ,  A61K31/7056 ,  A61K47/02 ,  A61K47/183

Abstract: This invention relates to kits, compositions, and formulations comprising AICA riboside and analogs thereof and methods of using the same. The kits may comprise the compositions and/or formulations within a pH range, in a sterilized form. The kits may further comprise containers with a second therapeutic agent. The kits and compositions herein can be used to prevent morbidity/mortality in a patient or to prevent/treat an ischemic condition, a condition regulated by adenosine, or a condition associated with reduced blood flow to a tissue in a patient.

Abstract translation: 本发明涉及包含AICA核苷及其类似物的试剂盒，组合物和制剂及其使用方法。 试剂盒可以包含在无菌形式的pH范围内的组合物和/或制剂。 试剂盒可以进一步包含具有第二治疗剂的容器。 本文的试剂盒和组合物可以用于预防患者的发病/死亡或预防/治疗缺血性病症，由腺苷调节的病症或与流向患者组织的血流减少相关的病症。