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公开(公告)号：WO2020181051A1
公开(公告)日：2020-09-10
申请号：PCT/US2020/021122
申请日：2020-03-05
Applicant: WASHINGTON UNIVERSITY
Inventor： BENNETT, Kevin M. , BALDELOMAR, Edwin J.
Abstract: Among the various aspects of the present disclosure is the provision of methods and compositions for detecting recombinant cationic ferritin imaging agents. Also provided are transgenic microorganisms capable of synthesizing a recombinant ferritin imaging agent and methods of making the same. The imaging agents described herein can be used to effectively and noninvasively detect renal pathologies and are suitable for use in a number of imaging modalities.
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公开(公告)号：WO2019018615A1
公开(公告)日：2019-01-24
申请号：PCT/US2018/042849
申请日：2018-07-19
Applicant: AUBURN UNIVERSITY
Inventor： DAVID, Allan E. , YEH, Barry Jay
Abstract: A method of separating magnetic nanoparticles is described. The method comprises placing the magnetic nanoparticles in a periodic magnetic field. The periodic magnetic field varies between a first magnetic field strength and a second magnetic field strength that is higher than the first magnetic field strength. The nanoparticles may be superparamagnetic iron oxide nanoparticles.
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公开(公告)号：WO2018234659A1
公开(公告)日：2018-12-27
申请号：PCT/FR2018/051388
申请日：2018-06-13
Applicant: GERFLOR
Inventor： BOTTET, Richard , RAMUET, Patrick , HAMZAOUI, Eliès , DUBESSY, Christian
Abstract: L'invention concerne un procédé de fabrication en continu d'une couche décor pour revêtement de sol et mur comprenant au moinsles étapes suivantes consistant à: -faire défiler un support d'enduction; -enduire sur ledit support d'enduction une matrice comprenant des nacres magnétiquesnon-sphériques; -orienter les nacres magnétiques selon un motif défini à l'aide d'un moyen d'orientation magnétique disposé au contact ou à proximité du support d'enduction; -figer ladite matrice pour fixer l'orientation des nacres magnétiques et former ladite couche décor d'un revêtement de sol ou de mur.
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公开(公告)号：WO2018187609A1
公开(公告)日：2018-10-11
申请号：PCT/US2018/026313
申请日：2018-04-05
Applicant: BROWN UNIVERSITY , LAWRENCE LIVERMORE NATIONAL LABORATORY
Inventor： SUN, Shouheng , SHEN, Bo , MENDOZA-GARCIA, Adriana , MCCALL, Scott, K. , BAKER, Sarah, E.
Abstract: A method of stabilizing soft particles to create dried nanocomposite magnets includes coating a plurality of soft particles with a layer of Si0 2 , the soft particles being nanoparticles, creating a composite by mixing the soft particles with hard phase via a solution phase based assembly, annealing the composite, washing the composite with an alkaline solution to remove Si0 2 , and compacting the composite to create dried nanocomposite magnets.
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公开(公告)号：WO2018144599A1
公开(公告)日：2018-08-09
申请号：PCT/US2018/016233
申请日：2018-01-31
Applicant: REGENTS OF THE UNIVERSITY OF MINNESOTA , WU, Kai
Inventor： WU, Kai , WANG, Jian-Ping
CPC classification number: G01R33/12 , G01R33/1276
Abstract: An example system includes an excitation coil configured to simultaneously subject a sample volume comprising a plurality of magnetic nanoparticles to a first excitation field having a frequency ƒ H and a second excitation field having a frequency ƒ L , to generate a magnetic response including a plurality of harmonics from the sample volume. A detection coil is configured to output a response signal indicative of one or both of the plurality of harmonics or a phase lag. The example system includes a computing device configured to receive the response signal, extract one or both of the phase lag or predetermined harmonic components of the plurality of harmonics, and determine an average saturation magnetization, an average hydrodynamic volume, or a core state of the plurality of magnetic nanoparticles based on one or both of the phase lag or the predetermined harmonic components.
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Patent Agency Ranking
公开(公告)号：WO2018100344A1
公开(公告)日：2018-06-07
申请号：PCT/GB2017/053550
申请日：2017-11-27
Applicant: MAGNETIC LAMINATES LTD
Abstract: The present invention provides a method for producing a magnetic nanoparticle-coated laminate material. The method comprises coating a pair of opposed surfaces of a plurality of steel or iron/cobalt (Fe/Co) alloy film portions with a magnetic nanoparticle-containing coating. Each magnetic nanoparticle comprises a core and a shell covering at least a portion of the core. The shell and core are made of different materials selected from one or more of: iron, cobalt, nickel; and/or alloys comprising two or more of: iron, cobalt and/or nickel; and/or magnetic rare earth metals; and/or diamagnetic transition metals. The method further comprises stacking the coated film portions on top of each other such that a or each coated surface of each film portion is located adjacent a further coated surface of an adjacent film portion; and compressing the stacked coated film portions together to form a nanoparticle- coated laminate material.
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公开(公告)号：WO2018087517A1
公开(公告)日：2018-05-17
申请号：PCT/GB2017/053191
申请日：2017-10-24
Applicant: RICHARD SIGNS LTD
Inventor： CLARKE, Richard Anthony
Abstract: A magnetic wall cover (2) comprising a plurality of layers which comprise, in order: a flexible cover layer (4), a flexible magnetic sheet (6), a flexible compressible sheet (8) and an adhesive (10).
Abstract translation: （2），其包括多个层，所述多个层依次包括：柔性覆盖层（4），柔性磁性片（6），柔性可压缩片（8）和 一种粘合剂（10）。
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公开(公告)号：WO2018069667A1
公开(公告)日：2018-04-19
申请号：PCT/GB2017/052873
申请日：2017-09-26
Applicant: UNIVERSITY OF LEICESTER
Inventor： YANG, Shengfu
IPC: H01F1/00
CPC classification number: H01F1/0045 , H01F1/0072 , H01F1/06
Abstract: A method for preparing a magnetic material comprising the steps of: (a) obtaining atoms of one or more ferromagnetic, antiferromagnetic or ferrimagnetic materials; and (b) immersing the atoms in a volume of cryogenic fluid.
Abstract translation: 一种制备磁性材料的方法，包括以下步骤：（a）获得一种或多种铁磁材料，反铁磁材料或亚铁磁材料的原子; 和（b）将原子浸入一定量的低温流体中。
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公开(公告)号：WO2018053460A1
公开(公告)日：2018-03-22
申请号：PCT/US2017/052141
申请日：2017-09-19
Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
Inventor： SANOJYA, Gabriel E. , SEGALMAN, Rachel A. , MITRAGOTRI, Samir S.
CPC classification number: H01F1/0018
Abstract: Embodiments of the present disclosure describe a paramagnetic polymer composition comprising a polymer backbone, an ion covalently tethered to the polymer backbone, and a counter-ion, wherein at least one of the ion and counter-ion include one or more of a transition metal and rare-earth metal, wherein the counter-ion electrostatically associates with the tethered ion to form a paramagnetic polymer. Embodiments of the present disclosure further describe a method of forming a paramagnetic polymer comprising associating an ion covalently tethered to a polymer backbone with a counter-ion, wherein at least one of the tethered ion and counter-ion include one or more of a transition metal and rare-earth metal. Embodiments also describe contrast agents based on the paramagnetic polymers.
Abstract translation: 本公开的实施方案描述了一种顺磁性聚合物组合物，其包含聚合物主链，共价连接至聚合物主链的离子和抗衡离子，其中离子和抗衡离子中的至少一种包括 一种或多种过渡金属和稀土金属，其中抗衡离子与拴系离子静电缔合以形成顺磁性聚合物。 本公开的实施方式进一步描述了形成顺磁性聚合物的方法，其包括将共价连接到聚合物主链的离子与反离子缔合，其中系留离子和反离子中的至少一种包括一种或多种过渡金属 和稀土金属。 实施例还描述了基于顺磁性聚合物的造影剂。
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20.发明申请EUKARYOTISCHE ADULTE ZELLEN UMFASSEND EIN TRANSFEKTIONSSYSTEM UND DEREN HERSTELLUNG UND VERWENDUNG 审中-公开包含转染系统的真核成体细胞及其制备和使用
公开(公告)号：WO2018042019A1
公开(公告)日：2018-03-08
申请号：PCT/EP2017/072018
申请日：2017-09-01
Applicant: UNIVERSITÄT ROSTOCK
Inventor： STEINHOFF, Gustav , DAVID, Robert , MÜLLER, Paula , VORONINA, Natalia , HAUSBURG, Frauke
Abstract: Die vorliegende Erfindung betrifft eine eukaryotische adulte Zelle umfassend ein Transfektionssystem, wobei das Transfektionssystem (i) ein kationisches Polymer aufweisend Aminogruppen, welche zumindest teilweise biotinyliert sind, (ii) magnetische Nanopartikel mit daran gebundenen Streptavidin-Molekülen, (ii) mindestens eine Nukleinsäure, umfasst.
Abstract translation:
本发明涉及一种真核成年细胞，其包含含有被至少部分地生物素化的氨基的转染，转染（I）的阳离子聚合物，（ii）用链亲和素分子导航用途结合的磁性纳米粒子 （ii）至少一种核酸。
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