公开(公告)号：WO2011084494A2

公开(公告)日：2011-07-14

申请号：PCT/US2010/060529

申请日：2010-12-15

Applicant: TEXAS INSTRUMENTS INCORPORATED ,  TEXAS INSTRUMENTS JAPAN LIMITED ,  RAJENDRA, Gireesh ,  DAVIS, Timothy, D. ,  SIVADAS, Apu ,  FRECHETTE, Michel ,  KRISHNASWAMY, Thiagarajan ,  PENNISI, Salvatore ,  KUMAR, Rakesh ,  PATEL, Bijit, Thakorbhai ,  MUKHERJEE, Subhashish ,  SAHU, Debapriya

Inventor： RAJENDRA, Gireesh ,  DAVIS, Timothy, D. ,  SIVADAS, Apu ,  FRECHETTE, Michel ,  KRISHNASWAMY, Thiagarajan ,  PENNISI, Salvatore ,  KUMAR, Rakesh ,  PATEL, Bijit, Thakorbhai ,  MUKHERJEE, Subhashish ,  SAHU, Debapriya

IPC: H04W88/06 ,  H04B1/50

CPC classification number: H04B1/006

Abstract: Disclosed are a multi-mode transceiver (205) and a circuit (220) for operating the multi-mode transceiver. A multi-mode transceiver includes a first circuit (225) that is configurable to operate as one of a transmitter and a receiver in a first mode, and a second circuit (230) that is configurable to operate as one of the transmitter and the receiver in a second mode. The multi-mode transceiver includes a first element coupled to the first circuit. The multi-mode transceiver includes a second element coupled to the first element and one or more ports (250). The multi-mode transceiver also includes a first switch (325), coupled to the second element and to the second circuit, that is configurable to operate the transceiver in at least one of the first mode and the second mode in conjunction with the first element and the second element.

Abstract translation: 公开了用于操作多模式收发器的多模式收发器（205）和电路（220）。 一种多模式收发器包括可配置成作为第一模式中的发射器和接收器之一操作的第一电路（225）以及可配置为作为发射器和接收器之一操作的第二电路（230） 在第二种模式下。 多模式收发器包括耦合到第一电路的第一元件。 多模式收发器包括耦合到第一元件的第二元件和一个或多个端口（250）。 多模式收发器还包括耦合到第二元件和第二电路的第一开关（325），该第一开关（325）可配置为结合第一元件在第一模式和第二模式中的至少一个中操作收发器 和第二个元素。

公开(公告)号：WO2011062930A1

公开(公告)日：2011-05-26

申请号：PCT/US2010/056931

申请日：2010-11-17

Applicant: GLAXOSMITHKLINE LLC ,  GILMER, Tona ,  KUMAR, Rakesh ,  LAQUERRE, Sylvie

Inventor： GILMER, Tona ,  KUMAR, Rakesh ,  LAQUERRE, Sylvie

IPC: A61K31/397

CPC classification number: A61K31/519 ,  A61K9/2009 ,  A61K9/2013 ,  A61K9/2018 ,  A61K9/2054 ,  A61K9/2059 ,  A61K9/485 ,  A61K9/4858 ,  A61K31/436 ,  A61K31/439 ,  A61K45/06 ,  A61K2300/00

Abstract: A novel combination comprising the MEK inhibitor N-{3-[3-cyclopropyl-5-(2-fluoro-4-iodo- phenylamino)6,8-dimethyl;-2,4,7-trioxo-3,4,6,7-tetrahydro-2H-pyrido[4,3-d]pyrimidin-1 - yl]phenyl}acetamide, or a pharmaceutically acceptable salt or solvate thereof, with a mTOR inhibitor, pharmaceutical compositions comprising the same and methods of using such combinations and compositions in the treatment of conditions in which the inhibition of MEK and/or mTOR is beneficial, e.g. cancer.

Abstract translation: 包含MEK抑制剂N- {3- [3-环丙基-5-（2-氟-4-碘 - 苯基氨基）6,8-二甲基-2,4,7-三氧代-3,4,6 ，7-四氢-2H-吡啶并[4,3-d]嘧啶-1-基]苯基}乙酰胺或其药学上可接受的盐或溶剂合物与mTOR抑制剂，包含其的药物组合物和使用这些组合的方法 以及用于治疗MEK和/或mTOR的抑制有益的病症的组合物，例如， 癌症。

公开(公告)号：WO2011044415A1

公开(公告)日：2011-04-14

申请号：PCT/US2010/051909

申请日：2010-10-08

Applicant: GLAXOSMITHKLINE LLC ,  DUMBLE, Melissa ,  GILMER, Tona ,  KUMAR, Rakesh ,  LAQUERRE, Sylvie ,  LEBOWITZ, Peter, F. ,  MORRIS, Shannon, Renae

Inventor： DUMBLE, Melissa ,  GILMER, Tona ,  KUMAR, Rakesh ,  LAQUERRE, Sylvie ,  LEBOWITZ, Peter, F. ,  MORRIS, Shannon, Renae

IPC: A01N43/78 ,  A61K31/425

CPC classification number: A61K31/4155 ,  A61K31/506 ,  A61K45/06 ,  A61K2300/00

Abstract: The present invention relates to a method of treating cancer in a human and to pharmaceutical combinations useful in such treatment. In particular, the method relates to a cancer treatment method that includes administering N -{3-[5-(2-Amino-4-pyrimidinyl)-2-(1,1-dimethylethyl)-1,3-thiazol-4-yl]-2-fluorophenyl}-2,6-difluorobenzenesulfonamide or a pharmaceutically acceptable salt thereof, and N -{(1S)-2-amino-1-[(3-fluorophenyl)methyl]ethyl}-5-chloro-4-(4-chloro-1-methyl-1 H -pyrazol-5-yl)-2-thiophenecarboxamide, or a pharmaceutically acceptable salt thereof, to a human in need thereof.

Abstract translation: 本发明涉及一种治疗人类癌症的方法和用于治疗的药物组合物。 特别地，该方法涉及一种癌症治疗方法，其包括给予N- {3- [5-（2-氨基-4-嘧啶基）-2-（1,1-二甲基乙基）-1,3-噻唑-4-基） 吡啶-2-基] -2-氟苯基} -2,6-二氟苯磺酰胺或其药学上可接受的盐和N - {（1S）-2-氨基-1 - [（3-氟苯基）甲基]乙基} -5-氯-4 - （4-氯-1-甲基-1H-吡唑-5-基）-2-噻吩甲酰胺或其药学上可接受的盐。

公开(公告)号：WO2010113005A3

公开(公告)日：2010-10-07

申请号：PCT/IB2010/000675

申请日：2010-03-26

Applicant: COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH ,  SHARMA, Abhishek ,  SINHA, Arun, Kumar ,  KUMAR, Rakesh ,  SHARMA, Naina

Inventor： SHARMA, Abhishek ,  SINHA, Arun, Kumar ,  KUMAR, Rakesh ,  SHARMA, Naina

IPC: C07C41/30 ,  C07C43/215 ,  C07C43/23 ,  C07C49/84 ,  C07C51/38 ,  C07C59/52 ,  C07C59/68 ,  C07D317/54 ,  C07D333/16

Abstract: The present invention provides a method for the preparation of some novel multiconj ugated 2- or 4 -hydroxy substituted stilbenes. The method provides one pot multicomponent approach wherein 3-4 step reaction sequences viz. condensation, decarboxylation and Heck coupling occur simultaneously which results in an enhanced yield of desired products and reduced reaction times

公开(公告)号：WO2007089445A3

公开(公告)日：2007-08-09

申请号：PCT/US2007/001365

申请日：2007-01-19

Applicant: AMGEN INC. ,  OLINER, Jonathan ,  KENDALL, Richard ,  KUMAR, Rakesh

Inventor： OLINER, Jonathan ,  KENDALL, Richard ,  KUMAR, Rakesh

IPC: A61K31/506 ,  A61K39/395 ,  A61K31/00 ,  A61K38/00 ,  A61P35/00

Abstract: The invention provides methods for using Ang2 inhibitors in combination with VEGF inhibitors to treat disease. The invention also provides compositions, kits, formulations, and specific disease treatments relating thereto.

公开(公告)号：WO2007055822A2

公开(公告)日：2007-05-18

申请号：PCT/US2006/038012

申请日：2006-09-28

Applicant: SPECIALTY COATING SYSTEMS, INC. ,  HANEFELD, Phillip ,  HORST, Sven ,  MEISE, Markus ,  BOGNITZKI, Michael ,  GREINER, Andreas ,  KUMAR, Rakesh

Inventor： HANEFELD, Phillip ,  HORST, Sven ,  MEISE, Markus ,  BOGNITZKI, Michael ,  GREINER, Andreas ,  KUMAR, Rakesh

IPC: C07C25/13 ,  B22F7/02 ,  C07C19/08

CPC classification number: C07C22/08 ,  C07C17/269 ,  C07C17/35 ,  C07C17/354 ,  C07C2603/92 ,  C08G61/02 ,  C09D165/00 ,  Y10T428/12028

Abstract: Fluorinated paracyclophane compounds are disclosed. These compounds can have a trifluorinated moiety and can be utilized as precursor dimer compounds to produce polymeric coatings comprising copolymers of trifluorinated paraxylylene.

Abstract translation: 公开了氟化对环烷烃化合物。 这些化合物可以具有三氟化部分，并且可以用作前体二聚体化合物以产生包含三氟化对二甲苯的共聚物的聚合物涂层。

公开(公告)号：WO2007013885A2

公开(公告)日：2007-02-01

申请号：PCT/US2005/036585

申请日：2005-10-13

Applicant: SARNOFF CORPORATION ,  AGGARWAL, Manoj ,  SAWHNEY, Harpreet ,  KUMAR, Rakesh ,  SAMARASEKERA, Supun

Inventor： AGGARWAL, Manoj ,  SAWHNEY, Harpreet ,  KUMAR, Rakesh ,  SAMARASEKERA, Supun

IPC: B23K26/26

CPC classification number: G06T7/277 ,  G01S3/7864 ,  G06T7/251 ,  G06T2207/10016 ,  G06T2207/30196

Abstract: Method for tracking an object recorded within a selected frame of a sequence of frames of video data, using a plurality of layers, where at least one object layer of the plurality of layers represents the object includes initializing layer ownership probabilities for pixels of the selected frame using a non-parametric motion model, estimating a set of motion parameters of the plurality of layers for the selected frame using a parametric maximization algorithm and tracking the object. The non-parametric motion model is optical flow and includes warping the mixing probabilities, the appearances of the plurality of layers, and the observed pixel data from the pixels of the preceding frame to the pixels of the selected frame to initialize the layer ownership probabilities for the pixels of the selected frame.

Abstract translation: 用于使用多个层来跟踪记录在视频数据的帧的序列的选定帧内的对象的方法，其中多个层中的至少一个对象层表示对象包括初始化层 使用非参数运动模型对所选帧的像素的所有权概率，使用参数最大化算法估计所述多个层的一组运动参数并跟踪所述对象。 非参数运动模型是光流，并且包括使混合概率，多个层的出现以及从前一帧的像素到所选帧的像素的观察像素数据变形，以初始化用于 所选帧的像素。

公开(公告)号：WO2006023647A1

公开(公告)日：2006-03-02

申请号：PCT/US2005/029400

申请日：2005-08-18

Applicant: SARNOFF CORPORATION ,  PARAGANO, Vincent ,  KUMAR, Rakesh ,  HANNA, Keith J. ,  CHENG, Hui ,  ARPA, Aydin

Inventor： PARAGANO, Vincent ,  KUMAR, Rakesh ,  HANNA, Keith J. ,  CHENG, Hui ,  ARPA, Aydin

IPC: F41A33/00

CPC classification number: G09B7/02 ,  F41A33/00 ,  F41G3/26 ,  F41J5/10 ,  F41J5/14

Abstract: A method and system for performing automated training environment monitoring and evaluation. The training environment may include a mixed reality elements to enhance a training experience.

Abstract translation: 一种用于执行自动化培训环境监测和评估的方法和系统。 培训环境可能包括混合的现实要素，以增强培训经验。

公开(公告)号：WO2005018575A2

公开(公告)日：2005-03-03

申请号：PCT/US2004/027834

申请日：2004-08-26

Applicant: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM ,  VADLAMUDI, Ratna, K. ,  KUMAR, Rakesh ,  BALASENTHIL, Seetharaman

Inventor： VADLAMUDI, Ratna, K. ,  KUMAR, Rakesh ,  BALASENTHIL, Seetharaman

IPC: A61K

CPC classification number: C07K14/4705 ,  C12N15/113 ,  C12N2310/14

Abstract: The present disclosure relates to the field of cellular tumorigenesis and cancer biology. More specifically, the present disclosure relates to tumorigenesis and cancer in estrogen-responsive cell types, including cell types such as testis, ovary and uterine tissues, mammary gland, brain, skeletal muscle, and lung tissues. The present disclosure further relates to compositions including polypeptides, oligopeptides, petidomimetics, antibodies, and nucleic acids, and pharmaceutical compositions, diagnostic kits, and therapeutic kits useful in the diagnosis or treatment of turnorigenesis in estrogen-responsive cell types.

Abstract translation: 本公开涉及细胞肿瘤发生和癌症生物学领域。 更具体地，本公开涉及在雌激素反应性细胞类型中的肿瘤发生和癌症，包括诸如睾丸，卵巢和子宫组织，乳腺，脑，骨骼肌和肺组织的细胞类型。 本公开还涉及包含多肽，寡肽，比模拟物，抗体和核酸的组合物，以及可用于诊断或治疗雌激素反应性细胞类型中的转录因子的药物组合物，诊断试剂盒和治疗试剂盒。

公开(公告)号：WO2004114648A2

公开(公告)日：2004-12-29

申请号：PCT/US2004/019722

申请日：2004-06-21

Applicant: SARNOFF CORPORATION ,  SAMARASEKERA, Supun ,  KUMAR, Rakesh ,  HANNA, Keith ,  SAWHNEY, Harpreet ,  ARPA, Aydin ,  AGGARWAL, Manoj ,  PARAGANO, Vincent

Inventor： SAMARASEKERA, Supun ,  KUMAR, Rakesh ,  HANNA, Keith ,  SAWHNEY, Harpreet ,  ARPA, Aydin ,  AGGARWAL, Manoj ,  PARAGANO, Vincent

IPC: H04N

CPC classification number: G08B13/19689 ,  G08B13/19645 ,  G08B13/19691

Abstract: A scalable architecture for providing real-time multi-camera distributed video processing and visualization. An exemplary system comprises at least one video capture and storage system for capturing and storing a plurality of input videos, at least one vision based alarm system for detecting and reporting alarm situations or events, and at least one video rendering system (e.g., a video flashlight system) for displaying an alarm situation in a context that speeds up comprehension and response. One advantage of the present architecture is that these systems are all scalable, such that additional sensors (e.g., cameras, motion sensors, infrared sensors, chemical sensors, biological sensors, temperature sensors and like) can be added in large numbers without overwhelming the ability of security forces to comprehend the alarm situation.