Abstract:
Ein System zur Entleerung eines mit fließfähigem Medium gefüllten Behälters weist folgendes auf: einen Behälter (3), in welchem eine Homogenisierung von Produktmasse durch Mischen erfolgt; eine Austragsvorrichtung (4), die wandgängig mit einer Innenwand des Behälters (3) ausgebildet ist und nach der Beendigung des Mischens in den Behälter (3) eingebracht wird, und eine Einrichtung (5) zur derartigen Druckbeaufschlagung der Austragsvorrichtung (4), dass diese die homogenisierte/gemischte Produktmasse in Richtung zum Boden des Behälters (3) nach unten drückt, wo die homogenisierte/gemischte Produktmasse durch ein geöffnetes Auslassventil des Behälters (3) ausgetragen wird.
Abstract:
Verfahren zum Mischen wenigstens einer Probenlösung mit wenigstens einem Reagenz und Vorrichtung Die Erfindung betrifft ein Verfahren zum Mischen wenigstens einer Probenlösung(P)mit wenigstens einem Reagenz(R)in wenigstens einer Kammer (2) einer mikrofluidischen Cartridge (MC) sowie eine Vorrichtung zur Durchführung des Verfahrens. Erfindungsgemäß ist vorgesehen, dass wenigstens ein Reagenz (R) mittels wenigstens eines beweglichen Bauteils (11) der Probenlösung (P) zugeführt und mit dieser in Kontakt gebracht wird. Auf diese Weise kann der Verlust an Probeflüssigkeit (P) bzw. Analyt vermindert werden. Des Weiteren wird auch eine Vorrichtung zur Durchführung des Verfahrens vorgeschlagen.
Abstract:
A contiguous, elastic cover, for a dissolution - testing vessel, has a slit from a central opening to its outer edge. The cover may be placed around a stirring shaft by deforming the elastic cover to temporarily enlarge the slit. After returning to its original shape, the cover is placed over the vessel with the shaft free to rotate unimpeded within the central opening. The cover has a first raised annular disk on one side and a second raised annular disk on the other side, where the disks have different outer diameters to enable the cover to be used with differently sized vessels. The cover has a first opening having a first diameter and a second opening having a different, second diameter such that a conventional probe fits either at one depth within the first opening or at a different, second depth within the second opening.
Abstract:
A system and method are provided for large volume sample amplification adaptable for use with conventional PCR-based reactions as well as emulsion-based PCR reactions. A sample is retained in a pouch or flexible bag which permits bulk PCR amplification with efficient heat-transfer properties. For applications involving emulsion-based PCR amplification, the system and method provide improved uniformity in emulsion amplification and can be used to amplify large or small volume emulsions rapidly and reproducibly.
Abstract:
An emulsion generation apparatus and method for forming an emulsion are provided wherein a customized impeller design is adapted to form an emulsion with a desired droplet size that defines a desired volume. The emulsion generation apparatus provides improved uniformity in emulsion preparation and may be used to create large or small volume emulsions rapidly and reproducibly. A system and method are also provided for large volume sample amplification adaptable for use with conventional PCR-based reactions as well as emulsion-based PCR reactions and other reactions. For applications involving emulsion- based PCR amplification, the system and method provide improved uniformity in emulsion amplification and can be used to amplify large or small volume emulsions rapidly and reproducibly.
Abstract:
An enrichment module and method are provided for enriching a population of templated beads and separating them from non-templated beads. The method can include hybridizing a templated bead with an enrichment bead to form a complex, trapping the complex in a filtration medium, washing non-templated beads through the filtration medium while retaining the complex, and then eluting the templated bead from the complex. The module can include a column for enrichment and filtration material exhibiting desired size- exclusion properties.
Abstract:
A countertop apparatus dispenses hair coloring, developers and bleach in specified quantities and mixes them, substantially reducing the manual labor involved in performing such tasks. A housing has an upstanding back wall and a bottom wall. A plurality of hair color tube stations is mounted on a forward side of the back wall and a hair color tube squeezing device is positioned at each hair color tube station. The hair color tube squeezing device includes a pair of confronting rollers that engage the trailing end of an inverted hair color tube. A plurality of developer reservoirs and a bleach hopper are also mounted to the apparatus. First and second mixing bowls receive and mix hair coloring and developer at first and second stations, and a third mixing bowl receives and mixes bleach and developer at a third station. Operation of the apparatus is keypad-controlled.