公开(公告)号：WO2013028841A1

公开(公告)日：2013-02-28

申请号：PCT/US2012/052021

申请日：2012-08-23

Applicant: ETHICON ENDO-SURGERY, INC. ,  ORTIZ, Mark, S. ,  ZEINER, Mark S. ,  HARRIS, Jason L. ,  HOLCOMB, Matthew D. ,  STOKES, Michael, J.

Inventor： ORTIZ, Mark, S. ,  ZEINER, Mark S. ,  HARRIS, Jason L. ,  HOLCOMB, Matthew D. ,  STOKES, Michael, J.

IPC: A61F5/00

CPC classification number: A61F5/0076 ,  A61F5/0089

Abstract: Endoluminal sleeve device (1) for internally lining a section of the GI tract, comprising a sleeve (2) configured for deployment inside a GI tract, the sleeve (2) having walls of a flexible material defining a sleeve lumen (3), a proximal end (4) defining a proximal lumen opening (5), and a distal end (6) defining a distal lumen opening (7), a tubular anchoring portion (8) forming said proximal lumen end (4) and defining anchoring seats (9) delimited each one by an annular collar (11) forming an opening through which adjacent tissue portions (12) can be pulled into the anchoring seats (9), expansion means adapted to act on the tissue portions (12) arranged in the anchoring seats (9) such that the tissue portions (12) expand to a dimension greater than the opening of the annular collar (11).

Abstract translation: 用于内部衬里胃肠道部分的内腔套管装置（1），包括构造成用于部署在胃肠道内的套筒（2），所述套管（2）具有限定套管内腔（3）的柔性材料的壁， 限定近端腔开口（5）的近端（4）和限定远端内腔开口（7）的远端（6），形成所述近端内腔端部（4）的管状锚固部分（8） 9）通过形成开口的环形套环（11）限定，相邻组织部分（12）可以通过该开口被拉入锚固座（9），适于作用在布置在锚固中的组织部分（12）上的膨胀装置 座（9），使得组织部分（12）膨胀成大于环形套环（11）的开口的尺寸。

公开(公告)号：WO2012006306A3

公开(公告)日：2012-08-23

申请号：PCT/US2011043008

申请日：2011-07-06

Applicant: ETHICON ENDO SURGERY INC ,  HUANG ZHIFAN F ,  WITT DAVID A ,  BANKS RAYMOND M ,  DIETZ TIMOTHY G ,  MOOTOO MARY E ,  JOHNSON GREGORY W ,  SWAYZE JEFFREY S ,  HARRIS JASON L ,  STULEN FOSTER B ,  MALAVIYA PRASANNA ,  TIMM RICHARD W ,  HUNT JOHN V ,  THOMPSON SUZANNE E ,  MONSON GAVIN M ,  LAIRD ROBERT J ,  VAKHARIA OMAR J ,  SCHALL CHRISTOPHER J ,  KIMBALL CORY G ,  MIREL AL ,  CUMMINGS JOHN F ,  BECKMAN ANDREW T

Inventor： HUANG ZHIFAN F ,  WITT DAVID A ,  BANKS RAYMOND M ,  DIETZ TIMOTHY G ,  MOOTOO MARY E ,  JOHNSON GREGORY W ,  SWAYZE JEFFREY S ,  HARRIS JASON L ,  STULEN FOSTER B ,  MALAVIYA PRASANNA ,  TIMM RICHARD W ,  HUNT JOHN V ,  THOMPSON SUZANNE E ,  MONSON GAVIN M ,  LAIRD ROBERT J ,  VAKHARIA OMAR J ,  SCHALL CHRISTOPHER J ,  KIMBALL CORY G ,  MIREL AL ,  CUMMINGS JOHN F ,  BECKMAN ANDREW T

IPC: A61B18/14

CPC classification number: A61B18/1445 ,  A61B17/32 ,  A61B2017/003 ,  A61B2017/00309 ,  A61B2017/00323 ,  A61B2017/2902 ,  A61B2017/291 ,  A61B2017/2927 ,  A61B2018/00077 ,  A61B2018/00607 ,  A61B2018/0063 ,  A61B2018/1412 ,  A61B2018/1455 ,  A61B2018/1861 ,  A61B2034/305

Abstract: An electrosurgical instrument can comprise a handle, a shaft, and an end effector, wherein the end effector can be rotatably coupled to the shaft by an articulation joint. The instrument can further comprise a drive member and the articulation joint can comprise flexible support members which can be configured to support the drive member. The instrument can further comprise supply wires electrically coupled to electrodes in the end effector and a wire tensioning device configured to prevent the supply wires from accumulating slack within the articulation joint. The drive member can comprise a plurality of flexible layers wherein some of the layers can be comprised of an electrically insulative material and other layers can be comprised of an electrically conductive material which is in electrical communication with a cutting member in the end effector and/or electrodes positioned within the end effector. A surgical instrument can comprise a handle and an end effector, wherein the end effector can comprise first and second jaws which can be opened and closed in order to capture tissue therebetween. The surgical instrument can further comprise a shaft extending between the handle and the effector and means for articulating the end effector relative to the shaft. The articulating means can comprise a portion of the shaft which is rotatable about a first axis in order to articulate the end effector about a second axis. In at least one embodiment, the shaft can comprise a first portion including a cam and a second portion including a cam follower, wherein the rotation of the second portion and the interaction of the cam and cam follower can cause the second portion to pivot relative to the first portion.

Abstract translation: 电外科器械可以包括手柄，轴和端部执行器，其中末端执行器可以通过铰接接头可旋转地联接到轴。 仪器还可以包括驱动构件，并且铰接接头可以包括可配置成支撑驱动构件的柔性支撑构件。 仪器还可以包括电耦合到末端执行器中的电极的电线，以及配置成防止供电线在铰接接头内累积松弛的电线张紧装置。 驱动构件可以包括多个柔性层，其中一些层可以由电绝缘材料构成，并且其它层可以由与末端执行器中的切割构件电连通的导电材料和/或 位于末端执行器内的电极。 手术器械可以包括手柄和末端执行器，其中末端执行器可以包括可以打开和关闭的第一和第二钳口，以便在其间捕获组织。 外科器械还可以包括在手柄和执行器之间延伸的轴和用于相对于轴铰接端部执行器的装置。 所述铰接装置可以包括所述轴的可围绕第一轴线旋转的部分，以便使所述端部执行器围绕第二轴线铰接。 在至少一个实施例中，轴可以包括包括凸轮的第一部分和包括凸轮从动件的第二部分，其中第二部分的旋转和凸轮和凸轮从动件的相互作用可以使第二部分相对于 第一部分。

公开(公告)号：WO2012103286A1

公开(公告)日：2012-08-02

申请号：PCT/US2012/022651

申请日：2012-01-26

Applicant: ETHICON ENDO-SURGERY, INC. ,  HOLCOMB, Matthew, D. ,  HARRIS, Jason, L. ,  STOKES, Michael, J. ,  ZEINER, Mark, S. ,  O'KEEFE, Jonathan, B. ,  BOUDREAU, Keith, D. ,  CERIER, Jeffrey, C.

Inventor： HOLCOMB, Matthew, D. ,  HARRIS, Jason, L. ,  STOKES, Michael, J. ,  ZEINER, Mark, S. ,  O'KEEFE, Jonathan, B. ,  BOUDREAU, Keith, D. ,  CERIER, Jeffrey, C.

IPC: A61B17/068

CPC classification number: A61B17/0684 ,  A61B17/0644 ,  A61B17/0682 ,  A61B2017/0053 ,  A61B2017/00818 ,  A61B2017/0488 ,  A61B2017/0645 ,  A61B2017/0725

Abstract: A surgical fastener applier having a handle and a fastener housing extending from the handle. The housing contains at least one anvil movable within the staple housing, the anvil has a proximal position and a distal position. When in the distal position a distal end of the anvil extends distal to the distal end of the staple housing. The housing contains a plurality of surgical fasteners each of which in the shape of a loop. At least one of the fasteners is placed around a portion of the anvil when in the distal position. The applier has a first mechanism for moving the anvil distally after a fastener has been deployed, and a second mechanism for moving the anvil distally after a fastener has been deployed. The second means is independent of the first means.

Abstract translation: 具有手柄和从手柄延伸的紧固件外壳的手术紧固件施加器。 壳体包含至少一个在钉仓壳体内可移动的砧座，砧座具有近端位置和远端位置。 当处于远端位置时，砧座的远端延伸到钉仓远端的远端。 壳体包含多个环形形状的外科紧固件。 当处于远端位置时，至少一个紧固件放置在砧座的一部分周围。 施放器具有用于在紧固件展开之后向远侧移动砧座的第一机构，以及用于在紧固件展开后向远侧移动砧座的第二机构。 第二种手段是独立于第一种手段。

公开(公告)号：WO2012087723A1

公开(公告)日：2012-06-28

申请号：PCT/US2011/065026

申请日：2011-12-15

Applicant: ETHICON ENDO-SURGERY, INC. ,  STOKES, Michael, J. ,  ZEINER, Mark, S. ,  HARRIS, Jason, L. ,  ASHER, Ryan, M. ,  CRAINICH, Lawrence

Inventor： STOKES, Michael, J. ,  ZEINER, Mark, S. ,  HARRIS, Jason, L. ,  ASHER, Ryan, M. ,  CRAINICH, Lawrence

IPC: A61F5/00 ,  A61B17/04 ,  A61B17/12 ,  A61B17/128 ,  A61B17/00 ,  A61B17/30 ,  A61B18/08 ,  A61B17/072 ,  A61N7/02

CPC classification number: A61B18/1492 ,  A61B17/00234 ,  A61B18/08 ,  A61B2017/00296 ,  A61B2017/00349 ,  A61B2017/00353 ,  A61B2017/00818 ,  A61B2017/0409 ,  A61B2017/0417 ,  A61B2017/0419 ,  A61B2017/0488 ,  A61B2017/06052 ,  A61B2017/07221 ,  A61B2017/12018 ,  A61B2017/306 ,  A61B2018/00279 ,  A61B2018/00494 ,  A61B2018/0063 ,  A61B2018/142 ,  A61B2018/143 ,  A61F5/0083 ,  A61N7/022

Abstract: Devices and methods are provided for forming one or more plications in the walls of a body cavity. In particular, endoscopic devices and methods are provided for forming and/or securing endoluminal tissue folds to reduce the volume of the gastric cavity. An end effector that includes a tissue receiving cavity can be delivered to a desired surgical site to allow a tissue fold to be formed within the tissue receiving cavity. A fastener can be used to secure the adjacent layers of tissue that form the tissue fold. The tissue folds can be effective to limit the stomach's capacity and create a feeling of satiety.

Abstract translation: 提供了用于在体腔壁中形成一个或多个脓肿的装置和方法。 特别地，提供内窥镜装置和方法用于形成和/或固定腔内组织折叠以减小胃腔的体积。 包括组织接收腔的末端执行器可以被递送到期望的手术部位以允许在组织接收腔内形成组织折叠。 紧固件可用于固定形成组织折叠的相邻的组织层。 组织褶皱可以有效地限制胃的能力并产生饱腹感。

公开(公告)号：WO2011156257A2

公开(公告)日：2011-12-15

申请号：PCT/US2011/039239

申请日：2011-06-06

Applicant: ETHICON ENDO-SURGERY, INC. ,  DIETZ, Timothy, G. ,  WITT, David, A. ,  ALDRIDGE, Jeffrey, L. ,  HUANG, Zhifan, F. ,  MOOTOO, Mary, E. ,  BANKS, Raymond, M. ,  STULEN, Foster, B. ,  SWAYZE, Jeffrey, S. ,  MALAVIYA, Prasanna ,  JOHNSON, Gregory, W. ,  HARRIS, Jason, L. ,  GUERRA, Paul ,  NORVELL, David, K.

Inventor： DIETZ, Timothy, G. ,  WITT, David, A. ,  ALDRIDGE, Jeffrey, L. ,  HUANG, Zhifan, F. ,  MOOTOO, Mary, E. ,  BANKS, Raymond, M. ,  STULEN, Foster, B. ,  SWAYZE, Jeffrey, S. ,  MALAVIYA, Prasanna ,  JOHNSON, Gregory, W. ,  HARRIS, Jason, L. ,  GUERRA, Paul ,  NORVELL, David, K.

IPC: A61B18/14

CPC classification number: A61B18/1445 ,  A61B2018/00065 ,  A61B2018/00083 ,  A61B2018/00642 ,  A61B2018/00702 ,  A61B2018/00755 ,  A61B2018/00791 ,  A61B2018/00982 ,  A61B2018/1455 ,  A61B2090/065 ,  A61B2218/002

Abstract: An electrosurgical surgical instrument that includes an end effector, wherein the end effector can comprise first and second jaws which can be opened and closed in order to capture tissue therebetween. In various embodiments, the first and second jaws can comprise one or more electrodes configured to apply a voltage across the tissue, wherein at least one of the electrodes can comprise i) a conductive material positioned within a non-conductive, or high- resistance, material or ii) a pressure sensitive conductive material, or iii) a plurality of electrodes may each comprise of a positive temperature coefficient material having a different switching temperature or iv) electrodes can be independently and/or sequentially operated. During and/or after energizing the electrodes, a cutting member can be advanced to cut the tissue.

Abstract translation: 一种包括端部执行器的电外科手术器械，其中末端执行器可以包括可以打开和关闭的第一和第二钳口，以便在其间捕获组织。 在各种实施例中，第一和第二钳口可以包括被配置为跨组织施加电压的一个或多个电极，其中至少一个电极可以包括：i）定位在非导电或高电阻内的导电材料， 材料或ii）压敏导电材料，或iii）多个电极可以各自包含具有不同开关温度的正温度系数材料，或iv）电极可以独立地和/或顺序操作。 在电极通电期间和/或之后，切割构件可以前进以切割组织。

公开(公告)号：WO2011149893A2

公开(公告)日：2011-12-01

申请号：PCT/US2011/037678

申请日：2011-05-24

Applicant: ETHICON ENDO-SURGERY, INC. ,  ALBRECHT, Thomas, E. ,  ALDRIDGE, Jeffrey, L. ,  CONLON, Sean, P. ,  CROPPER, Michael, S. ,  HERRERA-DAVIS, Denzel, Z. ,  DLUGOS, Daniel, F. ,  HARRIS, Jason, L. ,  HESS, Christopher, J. ,  HUITEMA, Thomas, W. ,  HUNT, John, V. ,  MALAVIYA, Prasanna ,  ORTIZ, Mark, S. ,  OVERMYER, Mark, D. ,  PASTORELLI, Alessandro ,  ROBERTSON, Galen, C. ,  SHELTON, Frederick, E. ,  STOKES, Michael, J. ,  STULEN, Foster, B. ,  VOEGELE, James, W. ,  WEISENBURGH, William, B., II ,  WIDENHOUSE, Christopher, W. ,  WOODARD, James, A., Jr. ,  YATES, David, C. ,  ZEINER, Mark, S. ,  ZWOLINSKI, Andrew, M.

Inventor： ALBRECHT, Thomas, E. ,  ALDRIDGE, Jeffrey, L. ,  CONLON, Sean, P. ,  CROPPER, Michael, S. ,  HERRERA-DAVIS, Denzel, Z. ,  DLUGOS, Daniel, F. ,  HARRIS, Jason, L. ,  HESS, Christopher, J. ,  HUITEMA, Thomas, W. ,  HUNT, John, V. ,  MALAVIYA, Prasanna ,  ORTIZ, Mark, S. ,  OVERMYER, Mark, D. ,  PASTORELLI, Alessandro ,  ROBERTSON, Galen, C. ,  SHELTON, Frederick, E. ,  STOKES, Michael, J. ,  STULEN, Foster, B. ,  VOEGELE, James, W. ,  WEISENBURGH, William, B., II ,  WIDENHOUSE, Christopher, W. ,  WOODARD, James, A., Jr. ,  YATES, David, C. ,  ZEINER, Mark, S. ,  ZWOLINSKI, Andrew, M.

IPC: A61F2/04

CPC classification number: A61F5/0076 ,  A61F2/04 ,  A61F5/0013 ,  A61F5/0026 ,  A61F5/0079 ,  A61F2002/045

Abstract: Methods and devices create an intestinal braking effect, are non-invasive or minimally invasive, and may be reversible. These methods and devices are accomplished via stabilized implantable systems, and ingestible pills. In one embodiment, the implantable system comprises a device delivering a therapeutic substance to a target location within the gastrointestinal tract of a patient in order to initiate an intestinal braking effect which would promote sensations of satiety and stimulate excess weight loss for the patient.

Abstract translation: 方法和装置产生肠道制动效果，是非侵入性的或微创的，并且可以是可逆的。 这些方法和装置通过稳定的可植入系统和可摄取的药丸来实现。 在一个实施例中，可植入系统包括将治疗物质递送到患者的胃肠道内的目标位置的装置，以便开始肠促动作用，其将促进饱腹感，并刺激患者多余的体重减轻。

公开(公告)号：WO2011149877A2

公开(公告)日：2011-12-01

申请号：PCT/US2011/037658

申请日：2011-05-24

Applicant: ETHICON ENDO-SURGERY, INC. ,  ALBRECHT, Thomas, E. ,  ALDRIDGE, Jeffrey, L. ,  CONLON, Sean, P. ,  CROPPER, Michael, S. ,  HERRERA-DAVIS, Denzel, Z. ,  DLUGOS, Daniel, F., Jr. ,  HARRIS, Jason, L. ,  HESS, Christopher, J. ,  MALAVIYA, Prasanna ,  MARSH, Glenda, C. ,  ORTIZ, Mark, S. ,  OVERMYER, Mark, D. ,  PASTORELLI, Alessandro ,  ROBERTSON, Galen, C. ,  SHELTON, Frederick, E. ,  STOKES, Michael, J. ,  VOEGELE, James, W. ,  WEANER, Lauren, S. ,  WEISENBURGH, William, B. ,  WIDENHOUSE, Christopher, W. ,  WIDENHOUSE, Tamara, S., Vetro ,  WOODARD, James, A., Jr. ,  YATES, David, C. ,  ZEINER, Mark, S. ,  ZWOLINSKI, Andrew, M.

Inventor： ALBRECHT, Thomas, E. ,  ALDRIDGE, Jeffrey, L. ,  CONLON, Sean, P. ,  CROPPER, Michael, S. ,  HERRERA-DAVIS, Denzel, Z. ,  DLUGOS, Daniel, F., Jr. ,  HARRIS, Jason, L. ,  HESS, Christopher, J. ,  MALAVIYA, Prasanna ,  MARSH, Glenda, C. ,  ORTIZ, Mark, S. ,  OVERMYER, Mark, D. ,  PASTORELLI, Alessandro ,  ROBERTSON, Galen, C. ,  SHELTON, Frederick, E. ,  STOKES, Michael, J. ,  VOEGELE, James, W. ,  WEANER, Lauren, S. ,  WEISENBURGH, William, B. ,  WIDENHOUSE, Christopher, W. ,  WIDENHOUSE, Tamara, S., Vetro ,  WOODARD, James, A., Jr. ,  YATES, David, C. ,  ZEINER, Mark, S. ,  ZWOLINSKI, Andrew, M.

IPC: A61M37/00 ,  A61M5/168 ,  A61N1/36 ,  A61M5/00 ,  A61F2/00 ,  A61K31/20

CPC classification number: A61M31/002 ,  A61F2/04 ,  A61F5/0013 ,  A61F5/0026 ,  A61F2002/045 ,  A61K9/0065 ,  A61M5/14276 ,  A61M39/0208 ,  A61M2210/106 ,  A61M2210/1064 ,  A61N1/0509 ,  A61N1/36007 ,  A61N1/37205

Abstract: Methods and devices create an intestinal braking effect, are non-invasive or minimally invasive, and may be reversible. These methods and devices are accomplished via stabilized implantable systems and ingestible pills. In one embodiment, a method of producing satiety comprising the steps of accessing a gastrointestinal tract of a patient and implanting an intraintestinal therapeutic substance eluting implant. The implant is capable of eluting a satiety inducing substance selected from at least one of a nutrient, a specific satiety inducing bio-active substance, pancreatic polypeptides, free fatty acids, cholecystokinin, amino acids, glutamine, lipids, linoleic acid, or a combination thereof, from the implant into the gastrointestinal tract.

Abstract translation: 方法和装置产生肠道制动效果，是非侵入性的或微创的，并且可以是可逆的。 这些方法和装置通过稳定的可植入系统和可摄取的药丸来实现。 在一个实施方案中，产生饱腹感的方法包括以下步骤：进入患者的胃肠道并植入肠内治疗物质洗脱植入物。 植入物能够洗脱选自营养物，特定饱腹感生物活性物质，胰腺多肽，游离脂肪酸，缩胆囊素，氨基酸，谷氨酰胺，脂质，亚油酸或组合中的至少一种的饱腹感受物质 从植入物到胃肠道。

公开(公告)号：WO2010085732A3

公开(公告)日：2010-07-29

申请号：PCT/US2010/021953

申请日：2010-01-25

Applicant: ETHICON ENDO-SURGERY, INC. ,  HARRIS, Jason, L. ,  CRAINICH, Lawrence ,  STOKES, Michael, J.

Inventor： HARRIS, Jason, L. ,  CRAINICH, Lawrence ,  STOKES, Michael, J.

IPC: A61B17/068 ,  A61B17/072

Abstract: A surgical fastener applier having a handle and a fastener housing extending from the handle. The housing contains a plurality of surgical fasteners. The surgical fasteners have a base, and two legs extending away from the base, wherein the legs have distal end segments. The fastener has a first shape wherein the distal end segments bend towards each other so that they are adjacent and form the fastener into a first loop. The fastener has a second shape wherein the distal end segments are spaced apart from each other along substantially an entire length thereof. The fastener also has a third shape wherein the distal end segments bend towards each other in so that they are adjacent and form the fastener into a second loop wherein the second loop having a width greater than a width of the first loop. The applier includes a means for forming the fastener into the second and third shapes.

公开(公告)号：WO2010085725A1

公开(公告)日：2010-07-29

申请号：PCT/US2010/021929

申请日：2010-01-25

Applicant: ETHICON ENDO-SURGERY, INC. ,  HARRIS, Jason, L. ,  CRAINICH, Lawrence

Inventor： HARRIS, Jason, L. ,  CRAINICH, Lawrence

IPC: A61B17/064

CPC classification number: A61B17/0644 ,  A61B17/0682

Abstract: A surgical fastener having a base, and two legs extending away from the base. The legs have distal end segments. The fastener has a first shape wherein the distal end segments bend towards each other in so that they are adjacent and form the fastener into a first loop. The fastener has a second shape wherein the distal end segments are spaced apart from each other along substantially an entire length thereof. The fastener has a third shape wherein the distal end segments bend towards each other so that they are adjacent and form the fastener into a second loop, wherein the second loop has a width greater than a width of the first loop.

Abstract translation: 具有基部的外科紧固件和远离基部延伸的两条腿。 腿部具有远端部分。 紧固件具有第一形状，其中远端部分彼此弯曲成使得它们相邻并且将紧固件形成第一环。 紧固件具有第二形状，其中远端段在其大致整个长度上彼此间隔开。 紧固件具有第三形状，其中远端段彼此弯曲，使得它们相邻并且将紧固件形成第二回路，其中第二回路的宽度大于第一回路的宽度。

公开(公告)号：WO2010059399A2

公开(公告)日：2010-05-27

申请号：PCT/US2009/062643

申请日：2009-10-29

Applicant: ETHICON ENDO-SURGERY, INC. ,  ALBRECHT, Thomas, E. ,  HARRIS, Jason, L. ,  ORTIZ, Mark, S.

Inventor： ALBRECHT, Thomas, E. ,  HARRIS, Jason, L. ,  ORTIZ, Mark, S.

IPC: A61F5/00 ,  G06F19/00

CPC classification number: A61F5/004 ,  A61F5/0046 ,  G06F19/00 ,  G06F19/3481