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    METHODS AND SYSTEMS FOR LASER TREATMENT USING NON-UNIFORM OUTPUT BEAM
    61.
    发明申请
    METHODS AND SYSTEMS FOR LASER TREATMENT USING NON-UNIFORM OUTPUT BEAM 审中-公开
    使用非均匀输出光束激光治疗的方法和系统

    公开(公告)号：WO2006116141A1

    公开(公告)日：2006-11-02

    申请号：PCT/US2006/015180

    申请日：2006-04-21

    Applicant: CYNOSURE, INC. ,  MIRKOV, Mirko, G. ,  SIERRA, Rafael, A. ,  CHO, George, E.S.

    Inventor： MIRKOV, Mirko, G. ,  SIERRA, Rafael, A. ,  CHO, George, E.S.

    IPC: A61N5/067 ,  A61N5/06 ,  A61B18/20

    CPC classification number: A61N5/0616 ,  A61B18/203 ,  A61B2018/00011 ,  A61B2018/00452 ,  A61B2018/0047 ,  A61B2018/208 ,  A61B2018/2211 ,  G02B5/1885

    Abstract: Methods and apparatus for treatment, such as skin rejuvenation treatment, use non-uniform laser radiation. A high-intensity portion of the laser radiation causes collagen destruction and shrinkage within select portions of the treatment area, while a lower-intensity portion of the radiation causes fibroblast stimulation leading to collagen production across other portions of the treatment area. An output beam from a laser source, such as an Nd:YAG laser, is coupled into an optical system that modifies the beam to provide a large-diameter beam having a nonuniform energy profile, comprised of a plurality of high-intensity zones surrounded by lower-intensity zones within the treatment beam. The higher-intensity zones heat select portions of the target tissue to temperatures sufficient for a first treatment (e.g. collagen shrinkage), while the lower-intensity zones provide sufficient energy for a second treatment (e.g. stimulated collagen production). A large area of tissue, preferably 7-10 mm in diameter, can be treated simultaneously, while minimizing the risk of burning or other damage to the skin. In one embodiment, the invention uses a fiber bundle to provide a non-uniform energy output beam, hi another embodiment, the invention uses a diffractive lens array to produce the non-uniform output beam. A cooling system can also be integrated with the laser treatment system. A pulse light source can also be integrated with the laser treatment system in a combined skin rejuvenation therapy.

    Abstract translation: 治疗方法和设备，如皮肤复原治疗，使用不均匀的激光辐射。 激光辐射的高强度部分导致处理区域的选定部分内的胶原蛋白破坏和收缩，而辐射的较低强度部分引起成纤维细胞刺激，导致治疗区域的其它部分的胶原产生。 来自诸如Nd：YAG激光器的激光源的输出光束被耦合到光学系统中，该光学系统修改光束以提供具有不均匀能量分布的大直径光束，所述大直径光束包括被包围的多个高强度区域 处理梁内的较低强度区域。 较高强度区域将目标组织的部分热量选择为足以进行第一次处理（例如胶原收缩）的温度，而较低强度区域为第二次处理（例如刺激胶原产生）提供足够的能量。 可以同时治疗大面积的组织，优选直径为7-10mm，同时最小化对皮肤的燃烧或其它损伤的风险。 在一个实施例中，本发明使用纤维束来提供不均匀的能量输出束。在另一个实施例中，本发明使用衍射透镜阵列来产生不均匀的输出光束。 冷却系统也可以与激光治疗系统集成。 脉冲光源也可以与激光治疗系统整合在组合的皮肤年轻化疗法中。

    METHOD FOR PROTECTING A FIBER OPTIC PROBE AND THE RESULTING FIBER OPTIC PROBE
    66.
    发明申请
    METHOD FOR PROTECTING A FIBER OPTIC PROBE AND THE RESULTING FIBER OPTIC PROBE 审中-公开
    保护光纤探头和光纤光纤探头的方法

    公开(公告)号：WO0153856A3

    公开(公告)日：2001-11-29

    申请号：PCT/US9931335

    申请日：1999-11-02

    Applicant: SPECTRX INC

    Inventor： LINCOLN DANNY ,  HARRELL TIM ,  KUMAR KRISHNA ,  PAPP JOSEPH ,  FARQUHAR DAVID

    IPC: G02B6/06 ,  A61B1/00 ,  A61B18/22 ,  G02B6/04

    CPC classification number: G02B6/04 ,  A61B2018/2211

    Abstract: A fiber optic probe (110) is provided that includes a housing (160), at least one optical fiber (120) disposed within the housing, one end of each of the at least one optical fiber being disposed adjacent an opening in the housing forming a probe face, a binding agent (130) that binds the at least one optical fiber within the housing, and a protective coating (150) sealingly covering the probe face to prevent contaminants from contacting the at least one optical fiber. A method for protecting a fiber optic probe having a housing, at least one optical fiber being disposed adjacent an opening in the housing forming a probe face, and a binding agent that binds the at least one optical fiber within the housing, includes polishing the probe face to create a substantially flat probe face, cleaning the probe face after polishing the probe face and sealing the probe face with a protective coating.

    Abstract translation: 提供了一种光纤探针（110），其包括壳体（160），设置在壳体内的至少一个光纤（120），所述至少一个光纤中的每一个的一端被设置成邻近壳体成形中的开口 探针面，将所述至少一个光纤结合在所述壳体内的粘合剂（130）以及密封地覆盖所述探针面以防止污染物接触所述至少一个光纤的保护涂层（150）。 一种用于保护具有壳体的光纤探针的方法，至少一个光纤邻近形成探针面的壳体中的开口设置，以及将至少一个光纤结合在壳体内的粘合剂，包括抛光探针 面以产生基本上平坦的探针面，在抛光探针面之后清洁探针面，并用保护涂层密封探针面。

    THERAPEUTIC LASER SYSTEM OPERATING BETWEEN 1000 AND 1300 NM AND ITS USE
    67.
    发明申请
    THERAPEUTIC LASER SYSTEM OPERATING BETWEEN 1000 AND 1300 NM AND ITS USE 审中-公开
    1000和1300 NM之间的治疗激光系统及其使用

    公开(公告)号：WO01074230A2

    公开(公告)日：2001-10-11

    申请号：PCT/US2001/010238

    申请日：2001-03-30

    IPC: A61B17/00 ,  A61B18/00 ,  A61B18/20 ,  A61B18/22 ,  A61N5/06 ,  A61N5/067 ,  A61B

    CPC classification number: A61B18/22 ,  A61B2017/00084 ,  A61B2018/00005 ,  A61B2018/2211 ,  A61N5/0601 ,  A61N5/062 ,  A61N2005/0659 ,  A61N2005/067

    Abstract: Laser systems medical or cosmetic applications, comprising diode lasers or diode lasers with other solid state lasers which can deliver up to 30 cw or more, and which generally operate at more than wavelength within the range of 1000 to 1300 nm are presented. Individual emitter or emitter groups within the diode laser system can be powered independently. These laser systems provide maximum penetration depths for procedures such as Laser-induced Interstitial Tumor Therapy, alone or in conjunction with other therapies such as Photo-Dynamic Therapy, chemotherapy, or radiation therapy. Where beneficial for the procedure, the operating wavelength of the system can be changed without interruption. In some variants, active tissue cooling at the distal end of the delivery fibers is incorporated as well as individual feedback loops to control and stabilize the temperature induced in the tissue. To enhance thermal or photo effects and thereby increase efficiencies, absorbers can be administered and the laser system tuned to the specific absorption band of the absorber.

    Abstract translation: 激光系统医疗或化妆品应用包括二极管激光器或二极管激光器，其具有可提供高达30cw或更大的固态激光器，并且其通常在1000nm至1300nm范围内的波长下工作。 二极管激光系统内的单个发射极或发射极组可独立供电。 这些激光系统单独或与其他治疗如光动力疗法，化学疗法或放射治疗联合为激光诱导间质肿瘤治疗等手术提供最大的穿透深度。 有利于程序，可以不间断地改变系统的工作波长。 在一些变型中，引入递送纤维的远端处的活性组织冷却以及各个反馈回路以控制和稳定在组织中诱导的温度。 为了增强热效应或光效，从而提高效率，可以施用吸收剂，激光系统调谐到吸收器的特定吸收带。

    MULTI-CHANNEL TRANSMYOCARDIAL LASER REVASCULARIZATION
    69.
    发明申请
    MULTI-CHANNEL TRANSMYOCARDIAL LASER REVASCULARIZATION 审中-公开
    多通道转移激光修复

    公开(公告)号：WO99008612A1

    公开(公告)日：1999-02-25

    申请号：PCT/US1998/016450

    申请日：1998-08-14

    IPC: A61B17/00 ,  A61B17/22 ,  A61B18/22 ,  A61B18/24 ,  A61B17/36

    CPC classification number: A61B18/24 ,  A61B2017/00247 ,  A61B2017/22074 ,  A61B2018/00392 ,  A61B2018/2211 ,  A61B2018/2238 ,  A61B2018/2288

    Abstract: A bundle of fibers is employed to concurrently produce a plurality of channels (14a-14c) through the myocardium of a heart and into its left ventricle wherein each fiber (2) receives laser energy in its proximate end, has its distal end placed against the myocardium, and pressed through it upon the application of laser energy into the fibers; the individual fibers are constrained to follow different paths through the myocardium. The different paths may be parallel (19a-19e) or divergent (16a-16e).

    Abstract translation: 使用一束纤维同时产生通过心脏的心肌并进入其左心室的多个通道（14a-14c），其中每个纤维（2）在其近端接收激光能量，其远端抵靠 心肌，并在将激光能量施加到纤维中时通过它; 单个纤维被约束以遵循穿过心肌的不同路径。 不同的路径可以是平行的（19a-19e）或发散的（16a-16e）。

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