THIOIMIDATE COMPOUND AND USE THEREOF FOR CONTROLLING PESTS
    65.
    发明申请
    THIOIMIDATE COMPOUND AND USE THEREOF FOR CONTROLLING PESTS 审中-公开
    化合物及其用于控制​​PESTS的用途

    公开(公告)号:WO2008149962A1

    公开(公告)日:2008-12-11

    申请号:PCT/JP2008/060407

    申请日:2008-05-30

    Inventor: ITOH, Shigeyuki

    CPC classification number: C07C327/58 A01N37/52 C07C2602/28

    Abstract: The present invention provides a thioimidate compound having an excellent control efficacy against pests, which is represented by the formula (I): wherein R represents a C 6-12 bicycloalkyl group or a C 1-3 alkyl group substituted with a C 6-12 bicycloalkyl group; m represents an integer of 0 to 2; n represents an integer of 0 to 2; X represents a halogen atom, a C 1-3 alkyl group, a C 1-3 haloalkyl group a C 1-4 alkoxy group, or a nitro group, and two X's are the same or different when m is 2; and Z represents a halogen atom, a C 1-3 alkyl group, a C 1-3 haloalkyl group, or a C 1-4 alkoxy group, and two Z's are the same or different when n is 2.

    Abstract translation: 本发明提供了一种具有优良防治害虫的硫代亚氨酸酯化合物,其由式(I)表示:其中R表示C6-12双环烷基或被C6-12双环烷基取代的C1-3烷基; m表示0〜2的整数。 n表示0〜2的整数, X表示卤素原子,C 1-3烷基,C 1-3卤代烷基,C 1-4烷氧基或硝基,当m为2时,X表示相同或不同。 Z表示卤原子,C1-3烷基,C1-3卤代烷基或C1-4烷氧基,当n为2时,两个Z相同或不同。

    POLYHYDROQUINOLINE COMPOUNDS AND DIHYDROPYRIDINE COMPOUNDS FOR INHIBITING BETA-AMYLOID PRODUCTION
    66.
    发明申请
    POLYHYDROQUINOLINE COMPOUNDS AND DIHYDROPYRIDINE COMPOUNDS FOR INHIBITING BETA-AMYLOID PRODUCTION 审中-公开
    用于抑制β-淀粉样蛋白生成的多氢喹啉化合物和二氢吡啶化合物

    公开(公告)号:WO2008070875A3

    公开(公告)日:2008-11-27

    申请号:PCT/US2007087019

    申请日:2007-12-10

    CPC classification number: A61K31/47

    Abstract: Provided are methods of treating or reducing the risk of developing beta-amyloid production, beta-amyloid deposition, beta-amyloid neurotoxicity (including abnormal hyperphosphorylation of tau) and microgliosis associated with cerebral accumulation of Alzheimer s amyloid by administering therapeutically effective amounts of polyhydroquinoline and dihydropyridine compounds which decrease Abeta production in cells. Further provided are methods for diagnosing diseases associated with cerebral accumulation of Alzheimer s amyloid in animals or humans by administering diagnostically effective amounts of polyhydroquinoline and dihydropyridine compounds which decrease Abeta production in cells.

    Abstract translation: 提供了通过施用治疗有效量的聚氢喹啉或通过施用治疗有效量的多氢喹啉来治疗或减少与阿尔茨海默氏淀粉样蛋白的脑累积相关的β-淀粉样蛋白产生,β-淀粉样蛋白沉积,β-淀粉样蛋白神经毒性(包括tau的异常过度磷酸化)和小神经胶质细胞增生的风险的方法和 降低细胞中Abeta产量的二氢吡啶化合物。 进一步提供了通过给予诊断有效量的减少细胞中Abeta产生的聚氢喹啉和二氢吡啶化合物来诊断动物或人类中与阿尔茨海默氏淀粉状蛋白脑积累有关的疾病的方法。

    VIRUCIDAL COMPOSITION
    69.
    发明申请
    VIRUCIDAL COMPOSITION 审中-公开
    VIRUCIDAL组成

    公开(公告)号:WO2008049454A1

    公开(公告)日:2008-05-02

    申请号:PCT/EP2006/067651

    申请日:2006-10-23

    Inventor: BIERING, Holger

    Abstract: The invention relates to a virucidal composition comprising based on the composition from 80 to 99 wt-% of a C 2 - C 4 monoalcohol or a mixture thereof, from 0.1 to lower 2 wt-% of an organic acid, from 0.1 to 1 wt-% of an alkoxylated monoglyceride and/or alkoxylated diglyceride, wherein the pH value of the composition is from pH 3.3 to 5 and the remainder up to 100 wt-% is water. The invention further describes a method of inactivating viruses, and a product comprising the virucidal composition and means for applying it.

    Abstract translation: 本发明涉及杀病毒组合物,其包含基于组合物80至99重量%的C 2 -C 4亚烷基一元醇或其混合物,其为0.1至低于 2重量%的有机酸,0.1至1重量%的烷氧基化单酸甘油酯和/或烷氧基化甘油二酯,其中组合物的pH值为3.3至5,其余至100重量%为水 。 本发明还描述了灭活病毒的方法,以及包含杀病毒组合物的产品和用于施用病毒的装置。

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