公开(公告)号：WO2022197241A1

公开(公告)日：2022-09-22

申请号：PCT/SG2021/050149

申请日：2021-03-19

Applicant: WILMAR INTERNATIONAL LIMITED

Inventor： NG, Kian Hong ,  ONG, Wei Li ,  CHAN, Kam Lock ,  SUWANTO, Antonius

IPC: C12N1/20 ,  A23K10/12 ,  C12R1/125

Abstract: The present invention relates to a Bacillus subtilis strain isolate DSM33646 which is capable of propagating and secreting mannolytic enzymes to hydrolyse at least three forms of mannan polymers upon contact with solvent- extracted palm kernel meal. The present invention also relates to a method for producing an enriched palm- based animal feed having a reduced mannan polymer content by contacting palm kernel meal with the said bacteria strain isolate.

公开(公告)号：WO2022066104A1

公开(公告)日：2022-03-31

申请号：PCT/SG2021/050582

申请日：2021-09-24

Applicant: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH

Inventor： BIN HAJIS, Muhammad Irfan ,  CHEN, Liwei ,  ONG, Ting Xun Nicholas ,  CHEW, Wei Leong

IPC: C12Q1/6876 ,  C12Q1/70

Abstract: Disclosed herein is a primer set for a nucleic acid amplification analysis to detect a SARS-CoV-2 virus, the primer set is selected from the group consisting of Set 12 against Orf1ab 2'-0-ribose methyltransferase: SEQ ID No. 1, SEQ ID No. 2, SEQ ID No. 7 attached to SEQ ID No. 8 by a first linker, and SEQ ID No. 9 attached to SEQ ID No. 10 by a second linker; Set 10 against orf3a: SEQ ID No. 11, SEQ ID No. 12, SEQ ID No. 17 attached to SEQ ID No. 18 by a third linker, and SEQ ID No. 19 attached to SEQ ID No. 20 by a fourth linker; Set 20 against S gene: SEQ ID No. 21, SEQ ID No. 22, SEQ ID No. 27 attached to SEQ ID No. 28 by a fifth linker, and SEQ ID No. 29 attached to SEQ ID No. 30 by a sixth linker; and any combinations thereof. In specific embodiments, the nucleic acid amplification analysis is reverse transcription-loop mediated isothermal amplification (RT-LAMP).

公开(公告)号：WO2022039673A1

公开(公告)日：2022-02-24

申请号：PCT/SG2021/050481

申请日：2021-08-17

Applicant: LYTE VENTURES PTE. LTD.

Inventor： GOH, Hao Kwang, Dennis ,  HA, Kwang Yuen, Vincent ,  TANO, Henry ,  POH, Teck Boon, Bruno ,  NG, Zhiyi

IPC: G06Q30/04 ,  G06Q20/38 ,  G06Q20/14

Abstract: The present disclosure relates to payment service platform and computer-implemented method for aggregating income receivables for freelancers for advancement. The method comprises ascertaining an outstanding balance limit, which is advanceable to a freelancer, based on eligible outstanding receivables and various risk factors which are associated with the freelancer and/or transaction classifications of the outstanding eligible receivables.

公开(公告)号：WO2021201773A1

公开(公告)日：2021-10-07

申请号：PCT/SG2021/050173

申请日：2021-03-29

Applicant: NANYANG TECHNOLOGICAL UNIVERSITY

Inventor： LIU, Ai Qun ,  ZHANG, Hui ,  KWEK, Leong Chuan ,  JIANG, Xudong

IPC: G06N3/067 ,  G02F1/21

Abstract: Embodiments of the invention provide an apparatus and method for implementing a complex-valued neural network. The apparatus comprises a plurality of Mach-Zehnder interferometers (MZIs) integrated onto a chip, wherein the plurality of MZIs are arranged to form a signal preparation unit configured to divide an input light from a laser source into a plurality of light beams, and modulate an amplitude and/or a phase of each light beam to generate a plurality of input signals and a reference signal; a weighting unit configured to adjust a configuration of the MZIs which are used to form the weighting unit according to a weight value or a weight matrix to transform the generated input signals into at least one output signal; and a coherent detection unit configured to interfere each of the at least one output signal with the reference signal to obtain information encoded in the magnitude and/or the phase of the at least one output signal.

公开(公告)号：WO2021176360A1

公开(公告)日：2021-09-10

申请号：PCT/IB2021/051744

申请日：2021-03-02

Applicant: CRAFT HEALTH PTE LTD

Inventor： LIM, Seng Han ,  GOH, Wei Jiang

IPC: A61J3/06 ,  A61K9/00 ,  A61K9/20 ,  B33Y80/00

Abstract: A long release capsule for extended delivery of a drug to a patient in an ingestible capsule, including systems and method for producing the same are described herein. The long release capsule includes a buoyancy compartment to cause the capsule to float and a drug compartment with openings to release the drug at a predetermined rate. The capsule is either enteric in nature or coated with an enteric coating and floats in gastric fluid for a controllable period of time. At the end of the period of time the coating dissolves and the capsule fragmentizes and sinks within the gastric fluid.

公开(公告)号：WO2021101449A1

公开(公告)日：2021-05-27

申请号：PCT/SG2020/050678

申请日：2020-11-20

Applicant: CREATIVE TECHNOLOGY LTD

Inventor： LEE, Teck Chee ,  HII, Toh Onn Desmond ,  ESTEBAN, Jenny Afliccion

IPC: H04N21/233 ,  H04N21/2389 ,  H04N21/4363 ,  H04N21/439 ,  H04N21/81

Abstract: Systems and techniques are provided to transmit data over a digital interface between a sender and a receiver. The digital interface is configured for transmitting a primary type of data as opposed to a secondary type of data. Nevertheless, systems and techniques are provided where the secondary type of data can be transmitted in the digital interface. As such, the primary and/or secondary types of data are transmitted from the sender to the receiver via the digital interface. The primary and secondary types of data may be different and/or unrelated and could be any type of data including, but not limited to, audio data, general data, and bulk data. Yet, the received primary and secondary types of data are still useful after the transmission.

公开(公告)号：WO2021071438A1

公开(公告)日：2021-04-15

申请号：PCT/SG2020/050583

申请日：2020-10-12

Applicant: NATIONAL UNIVERSITY OF SINGAPORE

Inventor： GO, Maybelle Darlene Kho ,  YEW, Wen Shan

IPC: C12N9/00 ,  C12N15/52 ,  C12N1/21 ,  C07D307/91

Abstract: A method for producing a cannabinoid by contacting cannabigerolic acid with a cannabinoid synthase orthologue. The cannabinoid synthase orthologue is from an organism other than Cannabis sativa. Also disclosed is a recombinant cell of Saccharomyces cerevisiae or Pichia pastoris that includes in its genome a nucleic acid encoding the above cannabinoid synthase orthologue. The cannabinoid synthase orthologue is expressed in the recombinant cell in an active form.

公开(公告)号：WO2020159444A1

公开(公告)日：2020-08-06

申请号：PCT/SG2020/050043

申请日：2020-01-30

Applicant: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH

Inventor： LEE, Wenn-Chyau ,  RENIA, Laurent

IPC: A61K38/17 ,  A61P33/06

Abstract: The invention relates to a composition comprising insulin growth factor binding protein 7 (IGFBP7) for treating malaria or reducing the phenomenon of IRBC-endothelial cytoadherence. The composition can further comprise Von Willebrand Factor (VWF) and/or thrombospondin- 1 (TSP-1). The composition can also be used as an adjunct therapeutic agent alongside other anti-malarial drugs.

公开(公告)号：WO2020159438A1

公开(公告)日：2020-08-06

申请号：PCT/SG2020/050030

申请日：2020-01-22

Applicant: WILMAR INTERNATIONAL LIMITED

Inventor： LIM, Junliang Kevin

IPC: G01N33/03 ,  G01N33/28 ,  G06N7/00 ,  G01N30/02 ,  G01N21/65 ,  G06N3/02

Abstract: A method for processing lipid contents of at least one oil sample and simulating at least one training sample is provided. The method includes receiving a first dataset of values associated with lipid contents of the at least one oil sample; applying a multivariate mixture model to the first dataset of values to simulate an intermediate dataset; and simulating the at least one training sample based on at least part of the simulated intermediate dataset. Further, a method for predicting the blending formula is also provided. The prediction method includes receiving a dataset of values associated with lipid contents of a blended oil sample; and processing the dataset using a single prediction model capable of generating a prediction of at least two constituent oils in the blended oil sample. Further, a method for processing lipid contents of at least one oil sample to simulate at least one blend sample and determining compliance of the at least one blend sample with a prescribed requirement is provided, in which simulating the at least one blend sample based on a first dataset of values associated with lipid contents of the at least one oil sample.

公开(公告)号：WO2020145901A1

公开(公告)日：2020-07-16

申请号：PCT/SG2020/050017

申请日：2020-01-13

Applicant: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH

Inventor： CHENG, Yang ,  NEWELL, Evan

IPC: C07K7/06 ,  C12N5/0783 ,  A61K39/29 ,  A61K35/12 ,  A61P31/20

Abstract: The present invention relates to peptides and their ability to identify and bind to T cells specific for HBV-infected hepatocytes. In an first aspect of the invention, there is provided a peptide comprising an amino sequence selected from the group consisting of STLPETAVVRR, STLPETAVVR, STLPETTVVRR, STLPETTVIRR, STPPETTVVRR, STLPETTVVGR and STIPETTVVRR, wherein the peptide is derived from Hepatitis B virus core169 and is capable of binding HLA-A*1101 and when bound to HLA-A*1101 is capable of identifying T cells specific for Hepatitis B virus. In a second aspect of the invention, there is provided A T cell expressing a T cell receptor (TCR) molecule, wherein the TCR molecule comprises an amino acid sequence selected from the group comprising: CASGDSNSPLHF, CASSGGQIVYEQYF, CSARGGRGGDYTF and CASSQDWTEAFF, the T cell receptor is able to bind to a peptide according to the first aspect of the invention.