公开(公告)号：WO2023087105A1

公开(公告)日：2023-05-25

申请号：PCT/CA2022/051694

申请日：2022-11-16

Applicant: TELO GENOMICS HOLDINGS CORP.

Inventor： MAI, Sabine ,  LOUIS, Sherif ,  KNECHT, Hans

IPC: C12Q1/6809 ,  C12Q1/6841 ,  G16B15/10 ,  G16B25/00

Abstract: Provided are methods for prognosing a clinical outcome in a subject or diagnosing the subject with high-risk or stable smoldering multiple myeloma (SMM), comprising determining a 3D telomeres organization signature of a test sample from the subject, the test sample comprising plasma cells, applying a classification model to the 3D telomeres organization signature to obtain an output classification that is indicative of the clinical outcome or diagnosis of the subject. Also provided are methods for treating a subject with high-risk or stable SMM.

公开(公告)号：WO2023081996A1

公开(公告)日：2023-05-19

申请号：PCT/CA2022/051646

申请日：2022-11-07

Applicant: MCCAIN FOODS LIMITED

Inventor： GERROW, Sherri Lee

IPC: A23L7/10 ,  A21D13/04 ,  A23L19/00 ,  A23L19/10 ,  A23L19/18

Abstract: The present disclosure relates to a premix for food product such as hashbrown and croquettes, the premix comprising quinoa such as quinoa flakes, corn flour such as yellow corn flour, and rice flour. The present disclosure also relates to food products for cooking or par-cooking and food products comprising the premix of the present disclosure. Further, the present disclosure includes methods of preparing food products of the present disclosure.

公开(公告)号：WO2023077216A1

公开(公告)日：2023-05-11

申请号：PCT/CA2022/051607

申请日：2022-10-31

Applicant: BRIGHT ANGEL THERAPEUTICS INC.

Inventor： JAIKARAN, Dominic ,  SLASSI, Abdelmalik ,  SHELLEY, Mee ,  PLACZEK, Andrew ,  DING, Kejia ,  GE, Jinzhu ,  ARNS, Stephen ,  JAQUITH, James ,  CRAWFORD, Jason ,  HELLER, Markus ,  HSIEH, Tom ,  TAN, Jason ,  SHIDMOOSSAVEE, Fahimeh

IPC: C07D495/04 ,  A01N43/90 ,  A01N47/44 ,  A01P3/00 ,  A61K31/517 ,  A61K31/538 ,  A61K31/4985 ,  A61K31/5386 ,  A61P31/10 ,  C07D487/04 ,  C07D495/14 ,  C07D519/00

Abstract: The present application relates compounds of Formula (I): or pharmaceutically acceptable salts, solvates and/or prodrugs thereof, to compositions comprising these compounds or pharmaceutically acceptable salts, solvates and/or prodrugs thereof, and various uses in the treatment or prevention of fungal-related diseases, disorders or conditions.

公开(公告)号：WO2023065028A1

公开(公告)日：2023-04-27

申请号：PCT/CA2022/051540

申请日：2022-10-19

Applicant: RING RESCUE INC.

Inventor： HENNESSEY, Patrick ,  MACKEIL, Brad ,  CAMPBELL, Scott ,  ELLSMERE, Joseph ,  SPENCER, Kevin

IPC: B23D47/00 ,  B23D45/00 ,  B23D45/16 ,  F16P3/00

Abstract: A ring cutter for transecting a ring trapped on an appendage. The ring cutter includes a body, a motor housed in the body, a blade drivingly connected to the motor, a guard coupled to the body, a guard actuator drivingly connected to the guard and controlling a movement of the guard, a current sensor positioned to sense electrical current associated with the motor, and a processor communicatively coupled to the current sensor and the guard actuator. The blade has a rotation axis and a peripheral cutting edge. The guard is insertable between the ring and the appendage to position the ring between the guard and the blade. The processor is configured to: i) receive, from the current sensor, an electrical current reading associated with the motor, and ii) transmit, to the guard actuator, one or more commands to control the movement of the guard based on the electrical current reading.

公开(公告)号：WO2023044576A1

公开(公告)日：2023-03-30

申请号：PCT/CA2022/051415

申请日：2022-09-23

Applicant: TORNADO SPECTRAL SYSTEMS INC.

Inventor： FRASER, Shaun ,  BEHR, Bradford B. ,  KEMPER, Mark

IPC: G01N21/65 ,  G01J3/44

Abstract: Various embodiments are provided herein for a Raman analyzer system and associated method of analyzing a chemical process including a supercritical fluid extraction process or a solvent extraction process using a Raman analyzer system where the method involves generating light stimuli and providing the light stimuli to a sample of the chemical process; collecting scattered light from the sample; filtering the scattered light using one or more selected optical filters for selectively attenuating one or more wavelength sections for Raman analysis; detecting the filtered light; and generating one or more filtered Raman spectra of the detected light.

公开(公告)号：WO2023044556A1

公开(公告)日：2023-03-30

申请号：PCT/CA2022/050007

申请日：2022-01-05

Applicant: ENVERIC BIOSCIENCES CANADA INC.

Inventor： HAGEL, Jillian M. ,  FACCHINI, Peter J. ,  LING, Chang-chun

IPC: C07D209/16 ,  A61K31/4045 ,  A61P25/00 ,  C07D209/14 ,  C12N9/10 ,  C12N15/54 ,  C12P17/10

Abstract: Disclosed are novel aminated psilocybin derivative compounds and pharmaceutical and recreational drug formulations containing the same. The aminated psilocybin derivative compounds may be chemically synthesized.

公开(公告)号：WO2023019359A1

公开(公告)日：2023-02-23

申请号：PCT/CA2022/051253

申请日：2022-08-18

Applicant: SYMPHONI BIOTECH INC.

Inventor： LÉVESQUE, Vincent

IPC: G01N21/64 ,  A01G7/04

Abstract: Systems, methods and devices for controlling the growth of a plant are described herein. The systems include a photonic sensor and a computing device communicatively coupled to the photonic sensor. The photonic sensor includes an excitation pulse generator configured to generate an excitation pulse of light and direct it towards a target area of a plant. The sensor also includes a lens configured to receive fluorescent light from the target area of the plant and direct the fluorescent light to a focal point, a plurality of optical filters, each being configured to selectively transmit a selected wavelength range of the fluorescent light, the selected wavelength range indicating a molecular activity of the plant, and a photodiode configured to determine an intensity of the selected wavelength range of fluorescent light and convert the measured intensity to a digital signal to be transmitted as molecular activity data to the computing device.

公开(公告)号：WO2023015387A1

公开(公告)日：2023-02-16

申请号：PCT/CA2022/051218

申请日：2022-08-09

Applicant: LEJ INC.

Inventor： JEAN-FRANCOIS, Louis-Edgar

IPC: B26B19/38 ,  A45D24/36

Abstract: A clipper for use with a hair trimmer is provided herein. The clipper includes a first edge, a second edge, a first side and a second side. The first side is opposite to the second side. The first side and the second side extending between the first edge and the second edge. The first edge includes a first edge surface, a second edge surface, a hook portion and a blade portion. The first edge surface is opposite to the second edge surface. The hook portion extends from the first edge surface and the second edge surface and is configured to secure the clipper on the hair trimmer. The blade portion is positioned adjacent to the second edge surface.

公开(公告)号：WO2023000100A1

公开(公告)日：2023-01-26

申请号：PCT/CA2022/051128

申请日：2022-07-20

Applicant: CB INTERESTS INC.

Inventor： JASINSKI, Christof

IPC: B28D7/04 ,  B28D1/02 ,  B23D45/00 ,  B23D47/04 ,  B27B5/29

Abstract: Systems, devices, and methods for cutting a workpiece are described herein. The systems include a clamp having an elongate body having a top surface, a bottom surface, a first end and a second end, the elongate body being positioned above the workpiece and below a motor of the saw; a first connector configured to secure the first end of the elongate body to the base at a first side of the base; and a second connector configured to secure the second end of the elongate body to the base at a second side of the base. The first connector and the second connector provide for the clamp to move between a raised position where the elongate body is coupled to the base and disengaged from a top surface of the workpiece and a lowered position where the elongate body is coupled to the base and presses down on the top surface of the workpiece and secures the workpiece against the upper surface of the base when the workpiece is positioned between the first connector and the second connector.

公开(公告)号：WO2023000091A1

公开(公告)日：2023-01-26

申请号：PCT/CA2022/051118

申请日：2022-07-19

Applicant: MARKDOM INTERNATIONAL INC.

Inventor： SADR, Changize

IPC: B29C45/16 ,  B29C45/13 ,  B29C45/14

Abstract: A method of forming a hollow article includes injecting a first molding material into a first mold cavity at a first injection pressure to form a first molded shell and injecting a second molding material into a second mold cavity at a second injection pressure to form a second molded shell. The first molded shell has a first peripheral edge, and the second molded shell has a second peripheral edge. The method includes positioning the first shell and second shell into facing relation with the first and second peripheral edges in a third cavity, and injecting a third molding material into the third cavity at a third injection pressure to bond together the first and second shells along the first and second peripheral edges to form the hollow article. The third injection pressure is less than the first injection pressure by at least about 3.5 bar.